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CD79A (CD79a molecule)

Identity

Alias_namesIGA
CD79A antigen (immunoglobulin-associated alpha)
CD79a molecule, immunoglobulin-associated alpha
Alias_symbol (synonym)MB-1
Other alias
HGNC (Hugo) CD79A
LocusID (NCBI) 973
Atlas_Id 43891
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 41877120 and ends at 41881372 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  ALK -positive diffuse large B-cell lymphoma


External links

Nomenclature
HGNC (Hugo)CD79A   1698
LRG (Locus Reference Genomic)LRG_42
Cards
Entrez_Gene (NCBI)CD79A  973  CD79a molecule
AliasesIGA; MB-1
GeneCards (Weizmann)CD79A
Ensembl hg19 (Hinxton)ENSG00000105369 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105369 [Gene_View]  chr19:41877120-41881372 [Contig_View]  CD79A [Vega]
ICGC DataPortalENSG00000105369
TCGA cBioPortalCD79A
AceView (NCBI)CD79A
Genatlas (Paris)CD79A
WikiGenes973
SOURCE (Princeton)CD79A
Genetics Home Reference (NIH)CD79A
Genomic and cartography
GoldenPath hg38 (UCSC)CD79A  -     chr19:41877120-41881372 +  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD79A  -     19q13.2   [Description]    (hg19-Feb_2009)
EnsemblCD79A - 19q13.2 [CytoView hg19]  CD79A - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBICD79A [Mapview hg19]  CD79A [Mapview hg38]
OMIM112205   613501   
Gene and transcription
Genbank (Entrez)AF283770 AK223371 AK315337 BC018964 BC113731
RefSeq transcript (Entrez)NM_001783 NM_021601
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CD79A
Cluster EST : UnigeneHs.631567 [ NCBI ]
CGAP (NCI)Hs.631567
Alternative Splicing GalleryENSG00000105369
Gene ExpressionCD79A [ NCBI-GEO ]   CD79A [ EBI - ARRAY_EXPRESS ]   CD79A [ SEEK ]   CD79A [ MEM ]
Gene Expression Viewer (FireBrowse)CD79A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)973
GTEX Portal (Tissue expression)CD79A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11912   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP11912  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11912
Splice isoforms : SwissVarP11912
PhosPhoSitePlusP11912
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    ITAM_1 (PS51055)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Immunoglobulin    Phos_immunorcpt_sig_ITAM   
Domain families : Pfam (Sanger)ig (PF00047)    ITAM (PF02189)   
Domain families : Pfam (NCBI)pfam00047    pfam02189   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  ITAM (SM00077)  
Conserved Domain (NCBI)CD79A
DMDM Disease mutations973
Blocks (Seattle)CD79A
PDB (SRS)1CV9   
PDB (PDBSum)1CV9   
PDB (IMB)1CV9   
PDB (RSDB)1CV9   
Structural Biology KnowledgeBase1CV9   
SCOP (Structural Classification of Proteins)1CV9   
CATH (Classification of proteins structures)1CV9   
SuperfamilyP11912
Human Protein AtlasENSG00000105369
Peptide AtlasP11912
HPRD00203
IPIIPI00008473   IPI00218322   
Protein Interaction databases
DIP (DOE-UCLA)P11912
IntAct (EBI)P11912
FunCoupENSG00000105369
BioGRIDCD79A
STRING (EMBL)CD79A
ZODIACCD79A
Ontologies - Pathways
QuickGOP11912
Ontology : AmiGOadaptive immune response  transmembrane signaling receptor activity  protein binding  cytoplasm  multivesicular body  plasma membrane  integral component of plasma membrane  external side of plasma membrane  external side of plasma membrane  B cell receptor complex  B cell receptor complex  B cell differentiation  B cell differentiation  B cell proliferation  B cell activation  protein homodimerization activity  membrane raft  B cell receptor signaling pathway  B cell receptor signaling pathway  protein homotetramerization  
Ontology : EGO-EBIadaptive immune response  transmembrane signaling receptor activity  protein binding  cytoplasm  multivesicular body  plasma membrane  integral component of plasma membrane  external side of plasma membrane  external side of plasma membrane  B cell receptor complex  B cell receptor complex  B cell differentiation  B cell differentiation  B cell proliferation  B cell activation  protein homodimerization activity  membrane raft  B cell receptor signaling pathway  B cell receptor signaling pathway  protein homotetramerization  
Pathways : BIOCARTACTCF: First Multivalent Nuclear Factor [Genes]    BCR Signaling Pathway [Genes]    B Cell Receptor Complex [Genes]   
Pathways : KEGGB cell receptor signaling pathway    Primary immunodeficiency   
NDEx NetworkCD79A
Atlas of Cancer Signalling NetworkCD79A
Wikipedia pathwaysCD79A
Orthology - Evolution
OrthoDB973
GeneTree (enSembl)ENSG00000105369
Phylogenetic Trees/Animal Genes : TreeFamCD79A
HOVERGENP11912
HOGENOMP11912
Homologs : HomoloGeneCD79A
Homology/Alignments : Family Browser (UCSC)CD79A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD79A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD79A
dbVarCD79A
ClinVarCD79A
1000_GenomesCD79A 
Exome Variant ServerCD79A
ExAC (Exome Aggregation Consortium)CD79A (select the gene name)
Genetic variants : HAPMAP973
Genomic Variants (DGV)CD79A [DGVbeta]
DECIPHERCD79A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD79A 
Mutations
ICGC Data PortalCD79A 
TCGA Data PortalCD79A 
Broad Tumor PortalCD79A
OASIS PortalCD79A [ Somatic mutations - Copy number]
Cancer Gene: CensusCD79A 
Somatic Mutations in Cancer : COSMICCD79A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCD79A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch CD79A
DgiDB (Drug Gene Interaction Database)CD79A
DoCM (Curated mutations)CD79A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD79A (select a term)
intoGenCD79A
Cancer3DCD79A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM112205    613501   
Orphanet10310   
MedgenCD79A
Genetic Testing Registry CD79A
NextProtP11912 [Medical]
TSGene973
GENETestsCD79A
Target ValidationCD79A
Huge Navigator CD79A [HugePedia]
snp3D : Map Gene to Disease973
BioCentury BCIQCD79A
ClinGenCD79A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD973
Chemical/Pharm GKB GenePA26237
Clinical trialCD79A
Miscellaneous
canSAR (ICR)CD79A (select the gene name)
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD79A
EVEXCD79A
GoPubMedCD79A
iHOPCD79A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:49:16 CEST 2017

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