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CD81 (CD81 molecule)

Identity

Other namesCVID6
S5.7
TAPA1
TSPAN28
HGNC (Hugo) CD81
LocusID (NCBI) 975
Location 11p15.5
Location_base_pair Starts at 2398547 and ends at 2418649 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CD81   1701
Cards
Entrez_Gene (NCBI)CD81  975  CD81 molecule
GeneCards (Weizmann)CD81
Ensembl (Hinxton)ENSG00000110651 [Gene_View]  chr11:2398547-2418649 [Contig_View]  CD81 [Vega]
ICGC DataPortalENSG00000110651
cBioPortalCD81
AceView (NCBI)CD81
Genatlas (Paris)CD81
WikiGenes975
SOURCE (Princeton)NM_001297649 NM_004356
Genomic and cartography
GoldenPath (UCSC)CD81  -  11p15.5   chr11:2398547-2418649 +  11p15.5   [Description]    (hg19-Feb_2009)
EnsemblCD81 - 11p15.5 [CytoView]
Mapping of homologs : NCBICD81 [Mapview]
OMIM186845   613496   
Gene and transcription
Genbank (Entrez)AB209380 AI334163 BC002978 BC093047 BG397506
RefSeq transcript (Entrez)NM_001297649 NM_004356
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_023386 NT_009237 NW_001838018 NW_004929378
Consensus coding sequences : CCDS (NCBI)CD81
Cluster EST : UnigeneHs.54457 [ NCBI ]
CGAP (NCI)Hs.54457
Alternative Splicing : Fast-db (Paris)GSHG0004542
Alternative Splicing GalleryENSG00000110651
Gene ExpressionCD81 [ NCBI-GEO ]     CD81 [ SEEK ]   CD81 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP60033 (Uniprot)
NextProtP60033  [Medical]
With graphics : InterProP60033
Splice isoforms : SwissVarP60033 (Swissvar)
Domaine pattern : Prosite (Expaxy)TM4_1 (PS00421)   
Domains : Interpro (EBI)CD81_LEL [organisation]   Tetraspanin [organisation]   Tetraspanin/Peripherin [organisation]   Tetraspanin_CS [organisation]   Tetraspanin_EC2 [organisation]  
Related proteins : CluSTrP60033
Domain families : Pfam (Sanger)Tetraspannin (PF00335)   
Domain families : Pfam (NCBI)pfam00335   
DMDM Disease mutations975
Blocks (Seattle)P60033
PDB (SRS)1G8Q    1IV5    2AVZ   
PDB (PDBSum)1G8Q    1IV5    2AVZ   
PDB (IMB)1G8Q    1IV5    2AVZ   
PDB (RSDB)1G8Q    1IV5    2AVZ   
Human Protein AtlasENSG00000110651 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP60033
HPRD08924
IPIIPI00000190   IPI00555750   IPI00657752   IPI00975882   IPI00980190   IPI00977561   IPI00983214   IPI00979139   IPI00979839   IPI00982190   IPI00981672   IPI00978459   
Protein Interaction databases
DIP (DOE-UCLA)P60033
IntAct (EBI)P60033
FunCoupENSG00000110651
BioGRIDCD81
InParanoidP60033
Interologous Interaction database P60033
IntegromeDBCD81
STRING (EMBL)CD81
Ontologies - Pathways
Ontology : AmiGOactivation of MAPK activity  immunological synapse  protein binding  plasma membrane  integral component of plasma membrane  phosphatidylinositol biosynthetic process  protein localization  cell proliferation  positive regulation of cell proliferation  membrane  MHC class II protein complex binding  vesicle  positive regulation of 1-phosphatidylinositol 4-kinase activity  phosphatidylinositol metabolic process  viral entry into host cell  receptor-mediated virion attachment to host cell  positive regulation of peptidyl-tyrosine phosphorylation  regulation of immune response  extracellular vesicular exosome  
Ontology : EGO-EBIactivation of MAPK activity  immunological synapse  protein binding  plasma membrane  integral component of plasma membrane  phosphatidylinositol biosynthetic process  protein localization  cell proliferation  positive regulation of cell proliferation  membrane  MHC class II protein complex binding  vesicle  positive regulation of 1-phosphatidylinositol 4-kinase activity  phosphatidylinositol metabolic process  viral entry into host cell  receptor-mediated virion attachment to host cell  positive regulation of peptidyl-tyrosine phosphorylation  regulation of immune response  extracellular vesicular exosome  
Pathways : KEGGB cell receptor signaling pathway    Malaria    Hepatitis C   
Protein Interaction DatabaseCD81
Wikipedia pathwaysCD81
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CD81
snp3D : Map Gene to Disease975
SNP (GeneSNP Utah)CD81
SNP : HGBaseCD81
Genetic variants : HAPMAPCD81
Exome VariantCD81
1000_GenomesCD81 
ICGC programENSG00000110651 
Somatic Mutations in Cancer : COSMICCD81 
CONAN: Copy Number AnalysisCD81 
Mutations and Diseases : HGMDCD81
Mutations and Diseases : intOGenCD81
Genomic VariantsCD81  CD81 [DGVbeta]
dbVarCD81
ClinVarCD81
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM186845    613496   
MedgenCD81
GENETestsCD81
Disease Genetic AssociationCD81
Huge Navigator CD81 [HugePedia]  CD81 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCD81
Homology/Alignments : Family Browser (UCSC)CD81
Phylogenetic Trees/Animal Genes : TreeFamCD81
Chemical/Protein Interactions : CTD975
Chemical/Pharm GKB GenePA26240
Clinical trialCD81
Cancer Resource (Charite)ENSG00000110651
Other databases
Probes
Litterature
PubMed204 Pubmed reference(s) in Entrez
CoreMineCD81
iHOPCD81
OncoSearchCD81
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:43:25 CEST 2014

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