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CD86 (CD86 molecule)

Identity

Other namesB7-2
B7.2
B70
CD28LG2
LAB72
HGNC (Hugo) CD86
LocusID (NCBI) 942
Location 3q13.33
Location_base_pair Starts at 121774209 and ends at 121839988 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CD86   1705
Cards
Entrez_Gene (NCBI)CD86  942  CD86 molecule
GeneCards (Weizmann)CD86
Ensembl (Hinxton)ENSG00000114013 [Gene_View]  chr3:121774209-121839988 [Contig_View]  CD86 [Vega]
ICGC DataPortalENSG00000114013
cBioPortalCD86
AceView (NCBI)CD86
Genatlas (Paris)CD86
WikiGenes942
SOURCE (Princeton)NM_001206924 NM_001206925 NM_006889 NM_175862 NM_176892
Genomic and cartography
GoldenPath (UCSC)CD86  -  3q13.33   chr3:121774209-121839988 +  3q13.33   [Description]    (hg19-Feb_2009)
EnsemblCD86 - 3q13.33 [CytoView]
Mapping of homologs : NCBICD86 [Mapview]
OMIM601020   
Gene and transcription
Genbank (Entrez)AK291497 AK294663 AK301237 AK313103 AK316203
RefSeq transcript (Entrez)NM_001206924 NM_001206925 NM_006889 NM_175862 NM_176892
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_029928 NT_005612 NW_001838882 NW_004929311
Consensus coding sequences : CCDS (NCBI)CD86
Cluster EST : UnigeneHs.171182 [ NCBI ]
CGAP (NCI)Hs.171182
Alternative Splicing : Fast-db (Paris)GSHG0021087
Alternative Splicing GalleryENSG00000114013
Gene ExpressionCD86 [ NCBI-GEO ]     CD86 [ SEEK ]   CD86 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP42081 (Uniprot)
NextProtP42081  [Medical]
With graphics : InterProP42081
Splice isoforms : SwissVarP42081 (Swissvar)
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom [organisation]   Ig-like_fold [organisation]   Ig_V-set [organisation]   Ig_V-set_subgr [organisation]  
Related proteins : CluSTrP42081
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IGv (SM00406)  
DMDM Disease mutations942
Blocks (Seattle)P42081
PDB (SRS)1I85    1NCN   
PDB (PDBSum)1I85    1NCN   
PDB (IMB)1I85    1NCN   
PDB (RSDB)1I85    1NCN   
Human Protein AtlasENSG00000114013 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP42081
HPRD03011
IPIIPI00290621   IPI00473032   IPI00947322   IPI00397658   IPI00947161   IPI00922788   IPI00947013   
Protein Interaction databases
DIP (DOE-UCLA)P42081
IntAct (EBI)P42081
FunCoupENSG00000114013
BioGRIDCD86
InParanoidP42081
Interologous Interaction database P42081
IntegromeDBCD86
STRING (EMBL)CD86
Ontologies - Pathways
Ontology : AmiGOtoll-like receptor signaling pathway  receptor activity  protein binding  plasma membrane  immune response  epidermal growth factor receptor signaling pathway  cell-cell signaling  positive regulation of cell proliferation  fibroblast growth factor receptor signaling pathway  external side of plasma membrane  coreceptor activity  integral to membrane  modulation by virus of host morphology or physiology  T cell costimulation  Fc-epsilon receptor signaling pathway  T cell activation  B cell activation  positive regulation of lymphotoxin A biosynthetic process  intracellular membrane-bounded organelle  positive regulation of interleukin-2 biosynthetic process  innate immune response  positive regulation of interleukin-4 biosynthetic process  positive regulation of T-helper 2 cell differentiation  positive regulation of transcription, DNA-dependent  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  defense response to virus  
Ontology : EGO-EBItoll-like receptor signaling pathway  receptor activity  protein binding  plasma membrane  immune response  epidermal growth factor receptor signaling pathway  cell-cell signaling  positive regulation of cell proliferation  fibroblast growth factor receptor signaling pathway  external side of plasma membrane  coreceptor activity  integral to membrane  modulation by virus of host morphology or physiology  T cell costimulation  Fc-epsilon receptor signaling pathway  T cell activation  B cell activation  positive regulation of lymphotoxin A biosynthetic process  intracellular membrane-bounded organelle  positive regulation of interleukin-2 biosynthetic process  innate immune response  positive regulation of interleukin-4 biosynthetic process  positive regulation of T-helper 2 cell differentiation  positive regulation of transcription, DNA-dependent  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  defense response to virus  
Pathways : BIOCARTAThe Co-Stimulatory Signal During T-cell Activation [Genes]    Th1/Th2 Differentiation [Genes]   
Pathways : KEGGCell adhesion molecules (CAMs)    Toll-like receptor signaling pathway    Intestinal immune network for IgA production    Type I diabetes mellitus    Transcriptional misregulation in cancer    Autoimmune thyroid disease    Systemic lupus erythematosus    Rheumatoid arthritis    Allograft rejection    Graft-versus-host disease    Viral myocarditis   
Protein Interaction DatabaseCD86
Wikipedia pathwaysCD86
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CD86
snp3D : Map Gene to Disease942
SNP (GeneSNP Utah)CD86
SNP : HGBaseCD86
Genetic variants : HAPMAPCD86
Exome VariantCD86
1000_GenomesCD86 
ICGC programENSG00000114013 
Somatic Mutations in Cancer : COSMICCD86 
CONAN: Copy Number AnalysisCD86 
Mutations and Diseases : HGMDCD86
Genomic VariantsCD86  CD86 [DGVbeta]
dbVarCD86
ClinVarCD86
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM601020   
MedgenCD86
GENETestsCD86
Disease Genetic AssociationCD86
Huge Navigator CD86 [HugePedia]  CD86 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCD86
Homology/Alignments : Family Browser (UCSC)CD86
Phylogenetic Trees/Animal Genes : TreeFamCD86
Chemical/Protein Interactions : CTD942
Chemical/Pharm GKB GenePA26243
Clinical trialCD86
Cancer Resource (Charite)ENSG00000114013
Other databases
Probes
Litterature
PubMed175 Pubmed reference(s) in Entrez
CoreMineCD86
iHOPCD86
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 16:48:56 CEST 2014

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