CD93 (CD93 molecule)

2013-07-01  

Identity

HGNC
LOCATION
20p11.21
LOCUSID
ALIAS
C1QR1,C1qR(P),C1qRP,CDw93,ECSM3,MXRA4,dJ737E23.1
FUSION GENES

Other Information

Locus ID:

NCBI: 22918
MIM: 120577
HGNC: 15855
Ensembl: ENSG00000125810

Variants:

dbSNP: 22918
ClinVar: 22918
TCGA: ENSG00000125810
COSMIC: CD93

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125810ENST00000246006Q9NPY3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
217683502011Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins.43
121403652002C1qRp defines a new human stem cell population with hematopoietic and hepatic potential.34
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
119944792002Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q.24
188346072008A hantavirus causing hemorrhagic fever with renal syndrome requires gC1qR/p32 for efficient cell binding and infection.24
193721412009Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women.24
263877562015CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.22
197967972009Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency.20
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
232721292012The epidermal growth factor-like domain of CD93 is a potent angiogenic factor.18

Citation

Dessen P

CD93 (CD93 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53427/cd93