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CDC14A (cell division cycle 14A)

Identity

Alias_namesCDC10 (cell division cycle 10, S. cerevisiae, homolog)
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
Alias_symbol (synonym)Cdc14A1
Cdc14A2
cdc14
Other aliasDFNB105
hCDC14
HGNC (Hugo) CDC14A
LocusID (NCBI) 8556
Atlas_Id 40000
Location 1p21.2  [Link to chromosome band 1p21]
Location_base_pair Starts at 100352467 and ends at 100520277 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TXLNB (6q24.1) / CDC14A (1p21.2)TXLNB 6q24.1 / CDC14A 1p21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDC14A   1718
Cards
Entrez_Gene (NCBI)CDC14A  8556  cell division cycle 14A
AliasesDFNB105; cdc14; hCDC14
GeneCards (Weizmann)CDC14A
Ensembl hg19 (Hinxton)ENSG00000079335 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000079335 [Gene_View]  chr1:100352467-100520277 [Contig_View]  CDC14A [Vega]
ICGC DataPortalENSG00000079335
TCGA cBioPortalCDC14A
AceView (NCBI)CDC14A
Genatlas (Paris)CDC14A
WikiGenes8556
SOURCE (Princeton)CDC14A
Genetics Home Reference (NIH)CDC14A
Genomic and cartography
GoldenPath hg38 (UCSC)CDC14A  -     chr1:100352467-100520277 +  1p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDC14A  -     1p21.2   [Description]    (hg19-Feb_2009)
EnsemblCDC14A - 1p21.2 [CytoView hg19]  CDC14A - 1p21.2 [CytoView hg38]
Mapping of homologs : NCBICDC14A [Mapview hg19]  CDC14A [Mapview hg38]
OMIM603504   616958   
Gene and transcription
Genbank (Entrez)AA929031 AB209857 AF000367 AF064102 AF064103
RefSeq transcript (Entrez)NM_001319210 NM_001319211 NM_001319212 NM_003672 NM_033312 NM_033313
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDC14A
Cluster EST : UnigeneHs.127411 [ NCBI ]
CGAP (NCI)Hs.127411
Alternative Splicing GalleryENSG00000079335
Gene ExpressionCDC14A [ NCBI-GEO ]   CDC14A [ EBI - ARRAY_EXPRESS ]   CDC14A [ SEEK ]   CDC14A [ MEM ]
Gene Expression Viewer (FireBrowse)CDC14A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8556
GTEX Portal (Tissue expression)CDC14A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UNH5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UNH5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UNH5
Splice isoforms : SwissVarQ9UNH5
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
PhosPhoSitePlusQ9UNH5
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)DSPn    Dual-sp_phosphatase_cat-dom    Dual_Pase_CDC14A    Prot-tyrosine_phosphatase-like    Tyr_Pase_AS    Tyr_Pase_cat    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)    DSPn (PF14671)   
Domain families : Pfam (NCBI)pfam00782    pfam14671   
Domain families : Smart (EMBL)DSPc (SM00195)  PTPc_motif (SM00404)  
Conserved Domain (NCBI)CDC14A
DMDM Disease mutations8556
Blocks (Seattle)CDC14A
SuperfamilyQ9UNH5
Human Protein AtlasENSG00000079335
Peptide AtlasQ9UNH5
HPRD04614
IPIIPI00021145   IPI00219831   IPI00031770   IPI00217676   IPI01014023   IPI01012743   IPI00642427   
Protein Interaction databases
DIP (DOE-UCLA)Q9UNH5
IntAct (EBI)Q9UNH5
FunCoupENSG00000079335
BioGRIDCDC14A
STRING (EMBL)CDC14A
ZODIACCDC14A
Ontologies - Pathways
QuickGOQ9UNH5
Ontology : AmiGOspindle pole  phosphoprotein phosphatase activity  protein serine/threonine phosphatase activity  protein serine/threonine phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  centrosome  cytosol  regulation of exit from mitosis  protein tyrosine/serine/threonine phosphatase activity  cell proliferation  nuclear body  peptidyl-tyrosine dephosphorylation  mitotic spindle midzone assembly  cell division  kinocilium  cilium assembly  mitotic cell cycle arrest  mitotic spindle  
Ontology : EGO-EBIspindle pole  phosphoprotein phosphatase activity  protein serine/threonine phosphatase activity  protein serine/threonine phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  centrosome  cytosol  regulation of exit from mitosis  protein tyrosine/serine/threonine phosphatase activity  cell proliferation  nuclear body  peptidyl-tyrosine dephosphorylation  mitotic spindle midzone assembly  cell division  kinocilium  cilium assembly  mitotic cell cycle arrest  mitotic spindle  
Pathways : KEGGCell cycle   
NDEx NetworkCDC14A
Atlas of Cancer Signalling NetworkCDC14A
Wikipedia pathwaysCDC14A
Orthology - Evolution
OrthoDB8556
GeneTree (enSembl)ENSG00000079335
Phylogenetic Trees/Animal Genes : TreeFamCDC14A
HOVERGENQ9UNH5
HOGENOMQ9UNH5
Homologs : HomoloGeneCDC14A
Homology/Alignments : Family Browser (UCSC)CDC14A
Gene fusions - Rearrangements
Fusion : MitelmanTXLNB/CDC14A [6q24.1/1p21.2]  [t(1;6)(p21;q24)]  
Fusion: TCGATXLNB 6q24.1 CDC14A 1p21.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDC14A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC14A
dbVarCDC14A
ClinVarCDC14A
1000_GenomesCDC14A 
Exome Variant ServerCDC14A
ExAC (Exome Aggregation Consortium)CDC14A (select the gene name)
Genetic variants : HAPMAP8556
Genomic Variants (DGV)CDC14A [DGVbeta]
DECIPHERCDC14A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDC14A 
Mutations
ICGC Data PortalCDC14A 
TCGA Data PortalCDC14A 
Broad Tumor PortalCDC14A
OASIS PortalCDC14A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDC14A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDC14A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDC14A
DgiDB (Drug Gene Interaction Database)CDC14A
DoCM (Curated mutations)CDC14A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDC14A (select a term)
intoGenCDC14A
Cancer3DCDC14A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603504    616958   
Orphanet12047   
MedgenCDC14A
Genetic Testing Registry CDC14A
NextProtQ9UNH5 [Medical]
TSGene8556
GENETestsCDC14A
Target ValidationCDC14A
Huge Navigator CDC14A [HugePedia]
snp3D : Map Gene to Disease8556
BioCentury BCIQCDC14A
ClinGenCDC14A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8556
Chemical/Pharm GKB GenePA26254
Clinical trialCDC14A
Miscellaneous
canSAR (ICR)CDC14A (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDC14A
EVEXCDC14A
GoPubMedCDC14A
iHOPCDC14A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:27:34 CEST 2017

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