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CDC23 (cell division cycle 23)

Identity

Alias_namesCDC23 (cell division cycle 23, yeast, homolog)
cell division cycle 23 homolog (S. cerevisiae)
Alias_symbol (synonym)APC8
ANAPC8
CUT23
Other alias
HGNC (Hugo) CDC23
LocusID (NCBI) 8697
Atlas_Id 46505
Location 5q31.2  [Link to chromosome band 5q31]
Location_base_pair Starts at 137523337 and ends at 137549032 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KIF20A (5q31.2) / CDC23 (5q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDC23   1724
Cards
Entrez_Gene (NCBI)CDC23  8697  cell division cycle 23
AliasesANAPC8; APC8; CUT23
GeneCards (Weizmann)CDC23
Ensembl hg19 (Hinxton)ENSG00000094880 [Gene_View]  chr5:137523337-137549032 [Contig_View]  CDC23 [Vega]
Ensembl hg38 (Hinxton)ENSG00000094880 [Gene_View]  chr5:137523337-137549032 [Contig_View]  CDC23 [Vega]
ICGC DataPortalENSG00000094880
TCGA cBioPortalCDC23
AceView (NCBI)CDC23
Genatlas (Paris)CDC23
WikiGenes8697
SOURCE (Princeton)CDC23
Genetics Home Reference (NIH)CDC23
Genomic and cartography
GoldenPath hg19 (UCSC)CDC23  -     chr5:137523337-137549032 -  5q31.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CDC23  -     5q31.2   [Description]    (hg38-Dec_2013)
EnsemblCDC23 - 5q31.2 [CytoView hg19]  CDC23 - 5q31.2 [CytoView hg38]
Mapping of homologs : NCBICDC23 [Mapview hg19]  CDC23 [Mapview hg38]
OMIM603462   
Gene and transcription
Genbank (Entrez)AB011472 AF053977 AF191341 AK223250 AK291610
RefSeq transcript (Entrez)NM_004661
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_034772 NW_004929323
Consensus coding sequences : CCDS (NCBI)CDC23
Cluster EST : UnigeneHs.73625 [ NCBI ]
CGAP (NCI)Hs.73625
Alternative Splicing GalleryENSG00000094880
Gene ExpressionCDC23 [ NCBI-GEO ]   CDC23 [ EBI - ARRAY_EXPRESS ]   CDC23 [ SEEK ]   CDC23 [ MEM ]
Gene Expression Viewer (FireBrowse)CDC23 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8697
GTEX Portal (Tissue expression)CDC23
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJX2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJX2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJX2
Splice isoforms : SwissVarQ9UJX2
PhosPhoSitePlusQ9UJX2
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)APC8    TPR-contain_dom    TPR-like_helical_dom    TPR_1    TPR_repeat   
Domain families : Pfam (Sanger)ANAPC8 (PF04049)    TPR_1 (PF00515)    TPR_11 (PF13414)    TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam04049    pfam00515    pfam13414    pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)CDC23
DMDM Disease mutations8697
Blocks (Seattle)CDC23
PDB (SRS)4UI9    5A31   
PDB (PDBSum)4UI9    5A31   
PDB (IMB)4UI9    5A31   
PDB (RSDB)4UI9    5A31   
Structural Biology KnowledgeBase4UI9    5A31   
SCOP (Structural Classification of Proteins)4UI9    5A31   
CATH (Classification of proteins structures)4UI9    5A31   
SuperfamilyQ9UJX2
Human Protein AtlasENSG00000094880
Peptide AtlasQ9UJX2
HPRD07221
IPIIPI00005822   IPI00019237   IPI00939517   IPI00965718   IPI00965494   IPI00966020   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJX2
IntAct (EBI)Q9UJX2
FunCoupENSG00000094880
BioGRIDCDC23
STRING (EMBL)CDC23
ZODIACCDC23
Ontologies - Pathways
QuickGOQ9UJX2
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  intracellular  nucleoplasm  anaphase-promoting complex  cytosol  ubiquitin-dependent protein catabolic process  mitotic nuclear division  mitotic metaphase plate congression  metaphase/anaphase transition of mitotic cell cycle  regulation of exit from mitosis  regulation of mitotic metaphase/anaphase transition  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  protein K11-linked ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  intracellular  nucleoplasm  anaphase-promoting complex  cytosol  ubiquitin-dependent protein catabolic process  mitotic nuclear division  mitotic metaphase plate congression  metaphase/anaphase transition of mitotic cell cycle  regulation of exit from mitosis  regulation of mitotic metaphase/anaphase transition  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  protein K11-linked ubiquitination  
Pathways : KEGGCell cycle    Oocyte meiosis    Ubiquitin mediated proteolysis    Progesterone-mediated oocyte maturation    HTLV-I infection   
NDEx NetworkCDC23
Atlas of Cancer Signalling NetworkCDC23
Wikipedia pathwaysCDC23
Orthology - Evolution
OrthoDB8697
GeneTree (enSembl)ENSG00000094880
Phylogenetic Trees/Animal Genes : TreeFamCDC23
HOVERGENQ9UJX2
HOGENOMQ9UJX2
Homologs : HomoloGeneCDC23
Homology/Alignments : Family Browser (UCSC)CDC23
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDC23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC23
dbVarCDC23
ClinVarCDC23
1000_GenomesCDC23 
Exome Variant ServerCDC23
ExAC (Exome Aggregation Consortium)CDC23 (select the gene name)
Genetic variants : HAPMAP8697
Genomic Variants (DGV)CDC23 [DGVbeta]
DECIPHER (Syndromes)5:137523337-137549032  ENSG00000094880
CONAN: Copy Number AnalysisCDC23 
Mutations
ICGC Data PortalCDC23 
TCGA Data PortalCDC23 
Broad Tumor PortalCDC23
OASIS PortalCDC23 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDC23  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDC23
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDC23
DgiDB (Drug Gene Interaction Database)CDC23
DoCM (Curated mutations)CDC23 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDC23 (select a term)
intoGenCDC23
Cancer3DCDC23(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603462   
Orphanet
MedgenCDC23
Genetic Testing Registry CDC23
NextProtQ9UJX2 [Medical]
TSGene8697
GENETestsCDC23
Huge Navigator CDC23 [HugePedia]
snp3D : Map Gene to Disease8697
BioCentury BCIQCDC23
ClinGenCDC23
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8697
Chemical/Pharm GKB GenePA26258
Clinical trialCDC23
Miscellaneous
canSAR (ICR)CDC23 (select the gene name)
Probes
Litterature
PubMed77 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDC23
EVEXCDC23
GoPubMedCDC23
iHOPCDC23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:55:47 CEST 2017

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