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CDC37 (cell division cycle 37)

Identity

Alias_namesCDC37 (cell division cycle 37, S. cerevisiae, homolog)
CDC37 cell division cycle 37 homolog (S. cerevisiae)
cell division cycle 37 homolog (S. cerevisiae)
Alias_symbol (synonym)P50CDC37
Other alias
HGNC (Hugo) CDC37
LocusID (NCBI) 11140
Atlas_Id 40011
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 10501809 and ends at 10514271 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDC37 (19p13.2) / CDC37 (19p13.2)CDC37 (19p13.2) / ELL (19p13.11)CDC37 (19p13.2) / IL27RA (19p13.12)
CDC37 (19p13.2) / TKT (3p21.1)GPI (19q13.11) / CDC37 (19p13.2)PAX1 (20p11.22) / CDC37 (19p13.2)
TYK2 (19p13.2) / CDC37 (19p13.2)CDC37 19p13.2 / ELL 19p13.11TYK2 19p13.2 / CDC37 19p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDC37   1735
Cards
Entrez_Gene (NCBI)CDC37  11140  cell division cycle 37
AliasesP50CDC37
GeneCards (Weizmann)CDC37
Ensembl hg19 (Hinxton)ENSG00000105401 [Gene_View]  chr19:10501809-10514271 [Contig_View]  CDC37 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105401 [Gene_View]  chr19:10501809-10514271 [Contig_View]  CDC37 [Vega]
ICGC DataPortalENSG00000105401
TCGA cBioPortalCDC37
AceView (NCBI)CDC37
Genatlas (Paris)CDC37
WikiGenes11140
SOURCE (Princeton)CDC37
Genetics Home Reference (NIH)CDC37
Genomic and cartography
GoldenPath hg19 (UCSC)CDC37  -     chr19:10501809-10514271 -  19p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CDC37  -     19p13.2   [Description]    (hg38-Dec_2013)
EnsemblCDC37 - 19p13.2 [CytoView hg19]  CDC37 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBICDC37 [Mapview hg19]  CDC37 [Mapview hg38]
OMIM605065   
Gene and transcription
Genbank (Entrez)AM393285 AM393349 BC000083 BC008793 BC127212
RefSeq transcript (Entrez)NM_007065
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)CDC37
Cluster EST : UnigeneHs.160958 [ NCBI ]
CGAP (NCI)Hs.160958
Alternative Splicing GalleryENSG00000105401
Gene ExpressionCDC37 [ NCBI-GEO ]   CDC37 [ EBI - ARRAY_EXPRESS ]   CDC37 [ SEEK ]   CDC37 [ MEM ]
Gene Expression Viewer (FireBrowse)CDC37 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11140
GTEX Portal (Tissue expression)CDC37
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16543   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16543  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16543
Splice isoforms : SwissVarQ16543
PhosPhoSitePlusQ16543
Domains : Interpro (EBI)Cdc37    Cdc37_C    Cdc37_Hsp90-bd    Cdc37_N_dom   
Domain families : Pfam (Sanger)CDC37_C (PF08564)    CDC37_M (PF08565)    CDC37_N (PF03234)   
Domain families : Pfam (NCBI)pfam08564    pfam08565    pfam03234   
Domain families : Smart (EMBL)CDC37_C (SM01069)  CDC37_M (SM01070)  CDC37_N (SM01071)  
Conserved Domain (NCBI)CDC37
DMDM Disease mutations11140
Blocks (Seattle)CDC37
PDB (SRS)1US7    2K5B    2N5X    2W0G   
PDB (PDBSum)1US7    2K5B    2N5X    2W0G   
PDB (IMB)1US7    2K5B    2N5X    2W0G   
PDB (RSDB)1US7    2K5B    2N5X    2W0G   
Structural Biology KnowledgeBase1US7    2K5B    2N5X    2W0G   
SCOP (Structural Classification of Proteins)1US7    2K5B    2N5X    2W0G   
CATH (Classification of proteins structures)1US7    2K5B    2N5X    2W0G   
SuperfamilyQ16543
Human Protein AtlasENSG00000105401
Peptide AtlasQ16543
HPRD05456
IPIIPI00013122   
Protein Interaction databases
DIP (DOE-UCLA)Q16543
IntAct (EBI)Q16543
FunCoupENSG00000105401
BioGRIDCDC37
STRING (EMBL)CDC37
ZODIACCDC37
Ontologies - Pathways
QuickGOQ16543
Ontology : AmiGOregulation of cyclin-dependent protein serine/threonine kinase activity  protein tyrosine kinase activity  protein binding  cytoplasm  cytoplasm  cytosol  protein folding  protein targeting  posttranscriptional regulation of gene expression  peptidyl-tyrosine phosphorylation  protein kinase regulator activity  kinase binding  protein kinase binding  heat shock protein binding  ERBB2 signaling pathway  protein stabilization  unfolded protein binding  chaperone binding  Hsp90 protein binding  regulation of interferon-gamma-mediated signaling pathway  regulation of type I interferon-mediated signaling pathway  extracellular exosome  mitophagy in response to mitochondrial depolarization  HSP90-CDC37 chaperone complex  
Ontology : EGO-EBIregulation of cyclin-dependent protein serine/threonine kinase activity  protein tyrosine kinase activity  protein binding  cytoplasm  cytoplasm  cytosol  protein folding  protein targeting  posttranscriptional regulation of gene expression  peptidyl-tyrosine phosphorylation  protein kinase regulator activity  kinase binding  protein kinase binding  heat shock protein binding  ERBB2 signaling pathway  protein stabilization  unfolded protein binding  chaperone binding  Hsp90 protein binding  regulation of interferon-gamma-mediated signaling pathway  regulation of type I interferon-mediated signaling pathway  extracellular exosome  mitophagy in response to mitochondrial depolarization  HSP90-CDC37 chaperone complex  
Pathways : KEGGPI3K-Akt signaling pathway   
NDEx NetworkCDC37
Atlas of Cancer Signalling NetworkCDC37
Wikipedia pathwaysCDC37
Orthology - Evolution
OrthoDB11140
GeneTree (enSembl)ENSG00000105401
Phylogenetic Trees/Animal Genes : TreeFamCDC37
HOVERGENQ16543
HOGENOMQ16543
Homologs : HomoloGeneCDC37
Homology/Alignments : Family Browser (UCSC)CDC37
Gene fusions - Rearrangements
Fusion : MitelmanCDC37/ELL [19p13.2/19p13.11]  
Fusion : MitelmanTYK2/CDC37 [19p13.2/19p13.2]  [t(19;19)(p13;p13)]  
Fusion: TCGACDC37 19p13.2 ELL 19p13.11 LUAD
Fusion: TCGATYK2 19p13.2 CDC37 19p13.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDC37 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC37
dbVarCDC37
ClinVarCDC37
1000_GenomesCDC37 
Exome Variant ServerCDC37
ExAC (Exome Aggregation Consortium)CDC37 (select the gene name)
Genetic variants : HAPMAP11140
Genomic Variants (DGV)CDC37 [DGVbeta]
DECIPHER (Syndromes)19:10501809-10514271  ENSG00000105401
CONAN: Copy Number AnalysisCDC37 
Mutations
ICGC Data PortalCDC37 
TCGA Data PortalCDC37 
Broad Tumor PortalCDC37
OASIS PortalCDC37 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDC37  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDC37
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDC37
DgiDB (Drug Gene Interaction Database)CDC37
DoCM (Curated mutations)CDC37 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDC37 (select a term)
intoGenCDC37
Cancer3DCDC37(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605065   
Orphanet
MedgenCDC37
Genetic Testing Registry CDC37
NextProtQ16543 [Medical]
TSGene11140
GENETestsCDC37
Huge Navigator CDC37 [HugePedia]
snp3D : Map Gene to Disease11140
BioCentury BCIQCDC37
ClinGenCDC37
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11140
Chemical/Pharm GKB GenePA402
Clinical trialCDC37
Miscellaneous
canSAR (ICR)CDC37 (select the gene name)
Probes
Litterature
PubMed142 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDC37
EVEXCDC37
GoPubMedCDC37
iHOPCDC37
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:59:34 CET 2017

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