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CDC40 (cell division cycle 40)

Identity

Alias (NCBI)EHB3
PRP17
PRPF17
HGNC (Hugo) CDC40
HGNC Alias symbPRP17
EHB3
PRPF17
FLJ10564
HGNC Previous namecell division cycle 40 homolog (yeast)
 cell division cycle 40 homolog (S. cerevisiae)
LocusID (NCBI) 51362
Atlas_Id 57247
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 110180427 and ends at 110232230 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CDC40 (6q21) / METTL24 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)CDC40   17350
Cards
Entrez_Gene (NCBI)CDC40  51362  cell division cycle 40
AliasesEHB3; PRP17; PRPF17
GeneCards (Weizmann)CDC40
Ensembl hg19 (Hinxton)ENSG00000168438 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168438 [Gene_View]  ENSG00000168438 [Sequence]  chr6:110180427-110232230 [Contig_View]  CDC40 [Vega]
ICGC DataPortalENSG00000168438
TCGA cBioPortalCDC40
AceView (NCBI)CDC40
Genatlas (Paris)CDC40
WikiGenes51362
SOURCE (Princeton)CDC40
Genetics Home Reference (NIH)CDC40
Genomic and cartography
GoldenPath hg38 (UCSC)CDC40  -     chr6:110180427-110232230 +  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDC40  -     6q21   [Description]    (hg19-Feb_2009)
GoldenPathCDC40 - 6q21 [CytoView hg19]  CDC40 - 6q21 [CytoView hg38]
ImmunoBaseENSG00000168438
genome Data Viewer NCBICDC40 [Mapview hg19]  
OMIM605585   
Gene and transcription
Genbank (Entrez)AB208903 AF015044 AF038392 AF061241 AK001426
RefSeq transcript (Entrez)NM_015891
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDC40
Alternative Splicing GalleryENSG00000168438
Gene ExpressionCDC40 [ NCBI-GEO ]   CDC40 [ EBI - ARRAY_EXPRESS ]   CDC40 [ SEEK ]   CDC40 [ MEM ]
Gene Expression Viewer (FireBrowse)CDC40 [ Firebrowse - Broad ]
GenevisibleExpression of CDC40 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51362
GTEX Portal (Tissue expression)CDC40
Human Protein AtlasENSG00000168438-CDC40 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60508   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60508  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60508
Splice isoforms : SwissVarO60508
PhosPhoSitePlusO60508
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)PRPF17    WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)CDC40
DMDM Disease mutations51362
Blocks (Seattle)CDC40
PDB (RSDB)5MQF    5XJC    5YZG    5Z56    5Z57    6FF4    6FF7    6ICZ    6ID0    6ID1    6QDV   
PDB Europe5MQF    5XJC    5YZG    5Z56    5Z57    6FF4    6FF7    6ICZ    6ID0    6ID1    6QDV   
PDB (PDBSum)5MQF    5XJC    5YZG    5Z56    5Z57    6FF4    6FF7    6ICZ    6ID0    6ID1    6QDV   
PDB (IMB)5MQF    5XJC    5YZG    5Z56    5Z57    6FF4    6FF7    6ICZ    6ID0    6ID1    6QDV   
Structural Biology KnowledgeBase5MQF    5XJC    5YZG    5Z56    5Z57    6FF4    6FF7    6ICZ    6ID0    6ID1    6QDV   
SCOP (Structural Classification of Proteins)5MQF    5XJC    5YZG    5Z56    5Z57    6FF4    6FF7    6ICZ    6ID0    6ID1    6QDV   
CATH (Classification of proteins structures)5MQF    5XJC    5YZG    5Z56    5Z57    6FF4    6FF7    6ICZ    6ID0    6ID1    6QDV   
SuperfamilyO60508
Human Protein Atlas [tissue]ENSG00000168438-CDC40 [tissue]
Peptide AtlasO60508
IPIIPI00026307   IPI01018075   IPI00645857   IPI00646175   IPI00514602   
Protein Interaction databases
DIP (DOE-UCLA)O60508
IntAct (EBI)O60508
FunCoupENSG00000168438
BioGRIDCDC40
STRING (EMBL)CDC40
ZODIACCDC40
Ontologies - Pathways
QuickGOO60508
Ontology : AmiGOmRNA splicing, via spliceosome  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleoplasm  nucleoplasm  RNA export from nucleus  mRNA export from nucleus  nuclear speck  mRNA 3'-end processing  U2-type catalytic step 2 spliceosome  catalytic step 2 spliceosome  catalytic step 2 spliceosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleoplasm  nucleoplasm  RNA export from nucleus  mRNA export from nucleus  nuclear speck  mRNA 3'-end processing  U2-type catalytic step 2 spliceosome  catalytic step 2 spliceosome  catalytic step 2 spliceosome  
Pathways : KEGGSpliceosome   
NDEx NetworkCDC40
Atlas of Cancer Signalling NetworkCDC40
Wikipedia pathwaysCDC40
Orthology - Evolution
OrthoDB51362
GeneTree (enSembl)ENSG00000168438
Phylogenetic Trees/Animal Genes : TreeFamCDC40
HOGENOMO60508
Homologs : HomoloGeneCDC40
Homology/Alignments : Family Browser (UCSC)CDC40
Gene fusions - Rearrangements
Fusion : QuiverCDC40
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDC40 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC40
dbVarCDC40
ClinVarCDC40
MonarchCDC40
1000_GenomesCDC40 
Exome Variant ServerCDC40
GNOMAD BrowserENSG00000168438
Varsome BrowserCDC40
Genetic variants : HAPMAP51362
Genomic Variants (DGV)CDC40 [DGVbeta]
DECIPHERCDC40 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDC40 
Mutations
ICGC Data PortalCDC40 
TCGA Data PortalCDC40 
Broad Tumor PortalCDC40
OASIS PortalCDC40 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDC40  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCDC40
Mutations and Diseases : HGMDCDC40
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDC40
DgiDB (Drug Gene Interaction Database)CDC40
DoCM (Curated mutations)CDC40 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDC40 (select a term)
intoGenCDC40
Cancer3DCDC40(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605585   
Orphanet
DisGeNETCDC40
MedgenCDC40
Genetic Testing Registry CDC40
NextProtO60508 [Medical]
TSGene51362
GENETestsCDC40
Target ValidationCDC40
Huge Navigator CDC40 [HugePedia]
snp3D : Map Gene to Disease51362
BioCentury BCIQCDC40
ClinGenCDC40
Clinical trials, drugs, therapy
Protein Interactions : CTD51362
Pharm GKB GenePA134891332
Clinical trialCDC40
Miscellaneous
canSAR (ICR)CDC40 (select the gene name)
HarmonizomeCDC40
DataMed IndexCDC40
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDC40
EVEXCDC40
GoPubMedCDC40
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:05:13 CEST 2020

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