CDC42BPB (CDC42 binding protein kinase beta)

2006-10-01  

Identity

HGNC
LOCATION
14q32.32
LOCUSID
ALIAS
MRCKB
FUSION GENES

Other Information

Locus ID:

NCBI: 9578
MIM: 614062
HGNC: 1738
Ensembl: ENSG00000198752

Variants:

dbSNP: 9578
ClinVar: 9578
TCGA: ENSG00000198752
COSMIC: CDC42BPB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198752ENST00000361246Q9Y5S2
ENSG00000198752ENST00000361246A0A024R6N2
ENSG00000198752ENST00000558321A0A0U1RRC3
ENSG00000198752ENST00000559043H0YLY0

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
212401872011Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration.24
219497622011Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion.17
299982872018DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies.15
182635882008Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.13
201771452010Overexpression and unique rearrangement of VH2 transcripts in immunoglobulin variable heavy chain genes in ankylosing spondylitis patients.1

Citation

Dessen P

CDC42BPB (CDC42 binding protein kinase beta)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43198/cdc42bpb