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CDC42BPG (CDC42 binding protein kinase gamma)

Identity

Alias_namesCDC42 binding protein kinase gamma (DMPK-like)
Alias_symbol (synonym)HSMDPKIN
MRCKgamma
DMPK2
kappa-200
Other aliasKAPPA-200
MRCKG
HGNC (Hugo) CDC42BPG
LocusID (NCBI) 55561
Atlas_Id 61638
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 64824190 and ends at 64844569 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MAP4K2 (11q13.1) / CDC42BPG (11q13.1)PRKCZ (1p36.33) / CDC42BPG (11q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDC42BPG   29829
Cards
Entrez_Gene (NCBI)CDC42BPG  55561  CDC42 binding protein kinase gamma
AliasesDMPK2; HSMDPKIN; KAPPA-200; MRCKG; 
MRCKgamma
GeneCards (Weizmann)CDC42BPG
Ensembl hg19 (Hinxton)ENSG00000171219 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171219 [Gene_View]  chr11:64824190-64844569 [Contig_View]  CDC42BPG [Vega]
ICGC DataPortalENSG00000171219
TCGA cBioPortalCDC42BPG
AceView (NCBI)CDC42BPG
Genatlas (Paris)CDC42BPG
WikiGenes55561
SOURCE (Princeton)CDC42BPG
Genetics Home Reference (NIH)CDC42BPG
Genomic and cartography
GoldenPath hg38 (UCSC)CDC42BPG  -     chr11:64824190-64844569 -  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDC42BPG  -     11q13.1   [Description]    (hg19-Feb_2009)
EnsemblCDC42BPG - 11q13.1 [CytoView hg19]  CDC42BPG - 11q13.1 [CytoView hg38]
Mapping of homologs : NCBICDC42BPG [Mapview hg19]  CDC42BPG [Mapview hg38]
OMIM613991   
Gene and transcription
Genbank (Entrez)AY648038 BI793270 Y12337
RefSeq transcript (Entrez)NM_017525
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDC42BPG
Cluster EST : UnigeneHs.293590 [ NCBI ]
CGAP (NCI)Hs.293590
Alternative Splicing GalleryENSG00000171219
Gene ExpressionCDC42BPG [ NCBI-GEO ]   CDC42BPG [ EBI - ARRAY_EXPRESS ]   CDC42BPG [ SEEK ]   CDC42BPG [ MEM ]
Gene Expression Viewer (FireBrowse)CDC42BPG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55561
GTEX Portal (Tissue expression)CDC42BPG
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6DT37   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6DT37  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6DT37
Splice isoforms : SwissVarQ6DT37
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ6DT37
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    CNH (PS50219)    CRIB (PS50108)    PH_DOMAIN (PS50003)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)AGC-kinase_C    CNH_dom    CRIB_dom    Kinase-like_dom    MRCK_gamma    Myotonic_dystrophy_kinase_coil    PE/DAG-bd    PH_dom-like    PH_domain    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)C1_1 (PF00130)    CNH (PF00780)    DMPK_coil (PF08826)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00130    pfam00780    pfam08826    pfam00069   
Domain families : Smart (EMBL)C1 (SM00109)  CNH (SM00036)  PH (SM00233)  S_TK_X (SM00133)  S_TKc (SM00220)  
Domain structure : Prodom (Prabi Lyon)Myotonic_dystrophy_kinase_coil (PD011252)   
Conserved Domain (NCBI)CDC42BPG
DMDM Disease mutations55561
Blocks (Seattle)CDC42BPG
SuperfamilyQ6DT37
Human Protein AtlasENSG00000171219
Peptide AtlasQ6DT37
HPRD13013
IPIIPI00454910   
Protein Interaction databases
DIP (DOE-UCLA)Q6DT37
IntAct (EBI)Q6DT37
FunCoupENSG00000171219
BioGRIDCDC42BPG
STRING (EMBL)CDC42BPG
ZODIACCDC42BPG
Ontologies - Pathways
QuickGOQ6DT37
Ontology : AmiGOmagnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  ATP binding  microtubule organizing center  cytosol  protein phosphorylation  protein phosphorylation  cell leading edge  actin cytoskeleton reorganization  intracellular signal transduction  
Ontology : EGO-EBImagnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  ATP binding  microtubule organizing center  cytosol  protein phosphorylation  protein phosphorylation  cell leading edge  actin cytoskeleton reorganization  intracellular signal transduction  
NDEx NetworkCDC42BPG
Atlas of Cancer Signalling NetworkCDC42BPG
Wikipedia pathwaysCDC42BPG
Orthology - Evolution
OrthoDB55561
GeneTree (enSembl)ENSG00000171219
Phylogenetic Trees/Animal Genes : TreeFamCDC42BPG
HOVERGENQ6DT37
HOGENOMQ6DT37
Homologs : HomoloGeneCDC42BPG
Homology/Alignments : Family Browser (UCSC)CDC42BPG
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDC42BPG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC42BPG
dbVarCDC42BPG
ClinVarCDC42BPG
1000_GenomesCDC42BPG 
Exome Variant ServerCDC42BPG
ExAC (Exome Aggregation Consortium)CDC42BPG (select the gene name)
Genetic variants : HAPMAP55561
Genomic Variants (DGV)CDC42BPG [DGVbeta]
DECIPHERCDC42BPG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDC42BPG 
Mutations
ICGC Data PortalCDC42BPG 
TCGA Data PortalCDC42BPG 
Broad Tumor PortalCDC42BPG
OASIS PortalCDC42BPG [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCDC42BPG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDC42BPG
DgiDB (Drug Gene Interaction Database)CDC42BPG
DoCM (Curated mutations)CDC42BPG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDC42BPG (select a term)
intoGenCDC42BPG
Cancer3DCDC42BPG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613991   
Orphanet
MedgenCDC42BPG
Genetic Testing Registry CDC42BPG
NextProtQ6DT37 [Medical]
TSGene55561
GENETestsCDC42BPG
Target ValidationCDC42BPG
Huge Navigator CDC42BPG [HugePedia]
snp3D : Map Gene to Disease55561
BioCentury BCIQCDC42BPG
ClinGenCDC42BPG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55561
Chemical/Pharm GKB GenePA134901493
Clinical trialCDC42BPG
Miscellaneous
canSAR (ICR)CDC42BPG (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDC42BPG
EVEXCDC42BPG
GoPubMedCDC42BPG
iHOPCDC42BPG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:42:56 CEST 2017

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