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CDC42SE1 (CDC42 small effector 1)

Identity

Alias_symbol (synonym)SCIP1
SPEC1
Other alias
HGNC (Hugo) CDC42SE1
LocusID (NCBI) 56882
Atlas_Id 61643
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 151023447 and ends at 151032125 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AGPAT2 (9q34.3) / CDC42SE1 (1q21.3)C1orf56 (1q21.3) / CDC42SE1 (1q21.3)CDC42SE1 (1q21.3) / C1orf56 (1q21.3)
CDC42SE1 (1q21.3) / CDC42SE1 (1q21.3)CDC42SE1 (1q21.3) / KRAS (12p12.1)CDC42SE1 (1q21.3) / TNKS (8p23.1)
RARRES3 (11q12.3) / CDC42SE1 (1q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDC42SE1   17719
Cards
Entrez_Gene (NCBI)CDC42SE1  56882  CDC42 small effector 1
AliasesSCIP1; SPEC1
GeneCards (Weizmann)CDC42SE1
Ensembl hg19 (Hinxton)ENSG00000197622 [Gene_View]  chr1:151023447-151032125 [Contig_View]  CDC42SE1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197622 [Gene_View]  chr1:151023447-151032125 [Contig_View]  CDC42SE1 [Vega]
ICGC DataPortalENSG00000197622
TCGA cBioPortalCDC42SE1
AceView (NCBI)CDC42SE1
Genatlas (Paris)CDC42SE1
WikiGenes56882
SOURCE (Princeton)CDC42SE1
Genetics Home Reference (NIH)CDC42SE1
Genomic and cartography
GoldenPath hg19 (UCSC)CDC42SE1  -     chr1:151023447-151032125 -  1q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CDC42SE1  -     1q21.3   [Description]    (hg38-Dec_2013)
EnsemblCDC42SE1 - 1q21.3 [CytoView hg19]  CDC42SE1 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBICDC42SE1 [Mapview hg19]  CDC42SE1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF187845 AF286041 AF286592 AK054914 BC012796
RefSeq transcript (Entrez)NM_001038707 NM_020239
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)CDC42SE1
Cluster EST : UnigeneHs.656288 [ NCBI ]
CGAP (NCI)Hs.656288
Alternative Splicing GalleryENSG00000197622
Gene ExpressionCDC42SE1 [ NCBI-GEO ]   CDC42SE1 [ EBI - ARRAY_EXPRESS ]   CDC42SE1 [ SEEK ]   CDC42SE1 [ MEM ]
Gene Expression Viewer (FireBrowse)CDC42SE1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56882
GTEX Portal (Tissue expression)CDC42SE1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRR8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRR8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRR8
Splice isoforms : SwissVarQ9NRR8
PhosPhoSitePlusQ9NRR8
Domaine pattern : Prosite (Expaxy)CRIB (PS50108)   
Domains : Interpro (EBI)CRIB_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CDC42SE1
DMDM Disease mutations56882
Blocks (Seattle)CDC42SE1
SuperfamilyQ9NRR8
Human Protein AtlasENSG00000197622
Peptide AtlasQ9NRR8
HPRD16694
IPIIPI00024972   IPI00386978   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRR8
IntAct (EBI)Q9NRR8
FunCoupENSG00000197622
BioGRIDCDC42SE1
STRING (EMBL)CDC42SE1
ZODIACCDC42SE1
Ontologies - Pathways
QuickGOQ9NRR8
Ontology : AmiGOGTPase inhibitor activity  structural molecule activity  cytoplasm  cytoskeleton  plasma membrane  phagocytosis  signal transduction  regulation of cell shape  negative regulation of GTPase activity  
Ontology : EGO-EBIGTPase inhibitor activity  structural molecule activity  cytoplasm  cytoskeleton  plasma membrane  phagocytosis  signal transduction  regulation of cell shape  negative regulation of GTPase activity  
NDEx NetworkCDC42SE1
Atlas of Cancer Signalling NetworkCDC42SE1
Wikipedia pathwaysCDC42SE1
Orthology - Evolution
OrthoDB56882
GeneTree (enSembl)ENSG00000197622
Phylogenetic Trees/Animal Genes : TreeFamCDC42SE1
HOVERGENQ9NRR8
HOGENOMQ9NRR8
Homologs : HomoloGeneCDC42SE1
Homology/Alignments : Family Browser (UCSC)CDC42SE1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDC42SE1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC42SE1
dbVarCDC42SE1
ClinVarCDC42SE1
1000_GenomesCDC42SE1 
Exome Variant ServerCDC42SE1
ExAC (Exome Aggregation Consortium)CDC42SE1 (select the gene name)
Genetic variants : HAPMAP56882
Genomic Variants (DGV)CDC42SE1 [DGVbeta]
DECIPHER (Syndromes)1:151023447-151032125  ENSG00000197622
CONAN: Copy Number AnalysisCDC42SE1 
Mutations
ICGC Data PortalCDC42SE1 
TCGA Data PortalCDC42SE1 
Broad Tumor PortalCDC42SE1
OASIS PortalCDC42SE1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDC42SE1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDC42SE1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDC42SE1
DgiDB (Drug Gene Interaction Database)CDC42SE1
DoCM (Curated mutations)CDC42SE1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDC42SE1 (select a term)
intoGenCDC42SE1
Cancer3DCDC42SE1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCDC42SE1
Genetic Testing Registry CDC42SE1
NextProtQ9NRR8 [Medical]
TSGene56882
GENETestsCDC42SE1
Huge Navigator CDC42SE1 [HugePedia]
snp3D : Map Gene to Disease56882
BioCentury BCIQCDC42SE1
ClinGenCDC42SE1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56882
Chemical/Pharm GKB GenePA134875001
Clinical trialCDC42SE1
Miscellaneous
canSAR (ICR)CDC42SE1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDC42SE1
EVEXCDC42SE1
GoPubMedCDC42SE1
iHOPCDC42SE1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:58:53 CET 2017

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