CDC42SE2 (CDC42 small effector 2)

2013-11-01  

Identity

HGNC
LOCATION
5q31.1
LOCUSID
ALIAS
SPEC2
FUSION GENES

Other Information

Locus ID:

NCBI: 56990
HGNC: 18547
Ensembl: ENSG00000158985

Variants:

dbSNP: 56990
ClinVar: 56990
TCGA: ENSG00000158985
COSMIC: CDC42SE2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158985ENST00000360515Q9NRR3
ENSG00000158985ENST00000395246Q9NRR3
ENSG00000158985ENST00000502582H0Y9W5
ENSG00000158985ENST00000503291D6REL0
ENSG00000158985ENST00000505065Q9NRR3

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
170305542006Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia.26
170305542006Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia.26
188043462008Interaction between interleukin 3 and dystrobrevin-binding protein 1 in schizophrenia.10
238330642013Regulation of Cdc42 expression and signaling is critical for promoting corneal epithelial wound healing.7
158405832005The role of SPECs, small Cdc42-binding proteins, in F-actin accumulation at the immunological synapse.2

Citation

Dessen P

CDC42SE2 (CDC42 small effector 2)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53612/cdc42se2