| CDC5L (6p21.1) / PITPNC1 (17q24.2) | CDC5L (6p21.1) / SPATS1 (6p21.1) | CDC5L (6p21.1) / TMEM63B (6p21.1) |
|
CDC5L (6p21.1) / USF2 (19q13.12) | CDC5L (6p21.1) / ZNF638 (2p13.2) | HNRNPA2B1 (7p15.2) / CDC5L (6p21.1) |
|
LDB3 (10q23.2) / CDC5L (6p21.1) | USF2 (19q13.12) / CDC5L (6p21.1) | CDC5L 6p21.1 / PITPNC1 17q24.2 |
|
CDC5L 6p21.1 / SPATS1 6p21.1 | CDC5L 6p21.1 / TMEM63B 6p21.1 |
| Nomenclature |
HGNC (Hugo) | CDC5L 1743 |
| Cards |
Entrez_Gene (NCBI) | CDC5L 988 cell division cycle 5 like |
Aliases | CDC5; CDC5-LIKE; CEF1; PCDC5RP; |
| dJ319D22.1 |
GeneCards (Weizmann) | CDC5L |
Ensembl hg19 (Hinxton) | ENSG00000096401 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000096401 [Gene_View]  ENSG00000096401 [Sequence] chr6:44387514-44450424 [Contig_View] CDC5L [Vega] |
ICGC DataPortal | ENSG00000096401 |
TCGA cBioPortal | CDC5L |
AceView (NCBI) | CDC5L |
Genatlas (Paris) | CDC5L |
WikiGenes | 988 |
SOURCE (Princeton) | CDC5L |
Genetics Home Reference (NIH) | CDC5L |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | CDC5L - chr6:44387514-44450424 + 6p21.1 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | CDC5L - 6p21.1 [Description] (hg19-Feb_2009) |
GoldenPath | CDC5L - 6p21.1 [CytoView hg19] CDC5L - 6p21.1 [CytoView hg38] |
ImmunoBase | ENSG00000096401 |
Mapping of homologs : NCBI | CDC5L [Mapview hg19] CDC5L [Mapview hg38] |
OMIM | 602868 |
| Gene and transcription |
Genbank (Entrez) | AB007892 AK128737 AK299738 BC001568 BG187521 |
RefSeq transcript (Entrez) | NM_001253 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | CDC5L |
Cluster EST : Unigene | Hs.485471 [ NCBI ] |
CGAP (NCI) | Hs.485471 |
Alternative Splicing Gallery | ENSG00000096401 |
Gene Expression | CDC5L [ NCBI-GEO ] CDC5L [ EBI - ARRAY_EXPRESS ]
CDC5L [ SEEK ] CDC5L [ MEM ] |
Gene Expression Viewer (FireBrowse) | CDC5L [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 988 |
GTEX Portal (Tissue expression) | CDC5L |
Human Protein Atlas | ENSG00000096401-CDC5L [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q99459 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q99459 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q99459 |
Splice isoforms : SwissVar | Q99459 |
PhosPhoSitePlus | Q99459 |
Domaine pattern : Prosite (Expaxy) | HTH_MYB (PS51294) |
Domains : Interpro (EBI) | Cdc5p/Cef1 Homeobox-like_sf Myb_dom SANT/Myb |
Domain families : Pfam (Sanger) | Myb_Cef (PF11831) |
Domain families : Pfam (NCBI) | pfam11831 |
Domain families : Smart (EMBL) | SANT (SM00717) |
Conserved Domain (NCBI) | CDC5L |
DMDM Disease mutations | 988 |
Blocks (Seattle) | CDC5L |
PDB (RSDB) | 2DIM 2DIN 5MQF 5XJC |
PDB Europe | 2DIM 2DIN 5MQF 5XJC |
PDB (PDBSum) | 2DIM 2DIN 5MQF 5XJC |
PDB (IMB) | 2DIM 2DIN 5MQF 5XJC |
Structural Biology KnowledgeBase | 2DIM 2DIN 5MQF 5XJC |
SCOP (Structural Classification of Proteins) | 2DIM 2DIN 5MQF 5XJC |
CATH (Classification of proteins structures) | 2DIM 2DIN 5MQF 5XJC |
Superfamily | Q99459 |
Human Protein Atlas [tissue] | ENSG00000096401-CDC5L [tissue] |
Peptide Atlas | Q99459 |
HPRD | 04184 |
IPI | IPI00465294 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q99459 |
IntAct (EBI) | Q99459 |
FunCoup | ENSG00000096401 |
BioGRID | CDC5L |
STRING (EMBL) | CDC5L |
ZODIAC | CDC5L |
| Ontologies - Pathways |
QuickGO | Q99459 |
Ontology : AmiGO | mitotic cell cycle mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome Prp19 complex RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription corepressor binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding RNA binding protein binding nucleus nucleoplasm nucleoplasm DNA replication factor A complex cytoplasm DNA repair protein phosphatase 1 binding membrane nuclear speck protein kinase binding leucine zipper domain binding cellular response to fibroblast growth factor stimulus positive regulation of transcription by RNA polymerase II perinuclear region of cytoplasm U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome cellular response to interleukin-2 WD40-repeat domain binding signal transduction involved in DNA damage checkpoint cellular response to wortmannin cellular response to nerve growth factor stimulus cellular response to prolactin |
Ontology : EGO-EBI | mitotic cell cycle mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome Prp19 complex RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription corepressor binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding RNA binding protein binding nucleus nucleoplasm nucleoplasm DNA replication factor A complex cytoplasm DNA repair protein phosphatase 1 binding membrane nuclear speck protein kinase binding leucine zipper domain binding cellular response to fibroblast growth factor stimulus positive regulation of transcription by RNA polymerase II perinuclear region of cytoplasm U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome cellular response to interleukin-2 WD40-repeat domain binding signal transduction involved in DNA damage checkpoint cellular response to wortmannin cellular response to nerve growth factor stimulus cellular response to prolactin |
Pathways : KEGG | Spliceosome |
NDEx Network | CDC5L |
Atlas of Cancer Signalling Network | CDC5L |
Wikipedia pathways | CDC5L |
| Orthology - Evolution |
OrthoDB | 988 |
GeneTree (enSembl) | ENSG00000096401 |
Phylogenetic Trees/Animal Genes : TreeFam | CDC5L |
HOGENOM | Q99459 |
Homologs : HomoloGene | CDC5L |
Homology/Alignments : Family Browser (UCSC) | CDC5L |
| Gene fusions - Rearrangements |
Fusion : Mitelman | CDC5L/PITPNC1 [6p21.1/17q24.2]   |
Fusion : Mitelman | CDC5L/SPATS1 [6p21.1/6p21.1]  [t(6;6)(p21;p21)] |
Fusion : Mitelman | CDC5L/TMEM63B [6p21.1/6p21.1]  [t(6;6)(p21;p21)] |
Fusion Portal | CDC5L 6p21.1 PITPNC1 17q24.2 BRCA |
Fusion Portal | CDC5L 6p21.1 SPATS1 6p21.1 BRCA |
Fusion Portal | CDC5L 6p21.1 TMEM63B 6p21.1 BLCA |
Fusion : Quiver | CDC5L |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | CDC5L [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | CDC5L |
dbVar | CDC5L |
ClinVar | CDC5L |
1000_Genomes | CDC5L |
Exome Variant Server | CDC5L |
ExAC (Exome Aggregation Consortium) | ENSG00000096401 |
GNOMAD Browser | ENSG00000096401 |
Varsome Browser | CDC5L |
Genetic variants : HAPMAP | 988 |
Genomic Variants (DGV) | CDC5L [DGVbeta] |
DECIPHER | CDC5L [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | CDC5L |
| Mutations |
ICGC Data Portal | CDC5L |
TCGA Data Portal | CDC5L |
Broad Tumor Portal | CDC5L |
OASIS Portal | CDC5L [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | CDC5L [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | CDC5L |
Mutations and Diseases : HGMD | CDC5L |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search CDC5L |
DgiDB (Drug Gene Interaction Database) | CDC5L |
DoCM (Curated mutations) | CDC5L (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | CDC5L (select a term) |
intoGen | CDC5L |
Cancer3D | CDC5L(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 602868 |
Orphanet | |
DisGeNET | CDC5L |
Medgen | CDC5L |
Genetic Testing Registry | CDC5L
|
NextProt | Q99459 [Medical] |
TSGene | 988 |
GENETests | CDC5L |
Target Validation | CDC5L |
Huge Navigator |
CDC5L [HugePedia] |
snp3D : Map Gene to Disease | 988 |
BioCentury BCIQ | CDC5L |
ClinGen | CDC5L |
| Clinical trials, drugs, therapy |
---|
Chemical/Protein Interactions : CTD | 988 |
Chemical/Pharm GKB Gene | PA26270 |
Clinical trial | CDC5L |
| Miscellaneous |
---|
canSAR (ICR) | CDC5L (select the gene name) |
DataMed Index | CDC5L |
| Probes |
---|
| Litterature |
---|
PubMed | 132 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | CDC5L |
EVEX | CDC5L |
GoPubMed | CDC5L |
iHOP | CDC5L |