CDCA5 (cell division cycle associated 5)

2010-08-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
SORORIN
FUSION GENES

Other Information

Locus ID:

NCBI: 113130
MIM: 609374
HGNC: 14626
Ensembl: ENSG00000146670

Variants:

dbSNP: 113130
ClinVar: 113130
TCGA: ENSG00000146670
COSMIC: CDCA5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146670ENST00000275517Q96FF9
ENSG00000146670ENST00000275517A0A024R5D6
ENSG00000146670ENST00000404147B5MBX0
ENSG00000146670ENST00000524733H0YCL8
ENSG00000146670ENST00000525464H0YCT9
ENSG00000146670ENST00000527430H0YCZ9
ENSG00000146670ENST00000529290H0YCR8

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
S PhaseREACTOMER-HSA-69242
Establishment of Sister Chromatid CohesionREACTOMER-HSA-2468052
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385392472024CDCA5 promoted cell invasion and migration by activating TGF-β1 pathway in human ovarian cancer cells.0
389780582024CDCA5 accelerates progression of breast cancer by promoting the binding of E2F1 and FOXM1.0
385392472024CDCA5 promoted cell invasion and migration by activating TGF-β1 pathway in human ovarian cancer cells.0
389780582024CDCA5 accelerates progression of breast cancer by promoting the binding of E2F1 and FOXM1.0
372477192023KLF5-mediated CDCA5 expression promotes tumor development and progression of epithelial ovarian carcinoma.0
372477192023KLF5-mediated CDCA5 expression promotes tumor development and progression of epithelial ovarian carcinoma.0
353734202022Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non-small cell lung cancer cells via p53-p21 signaling pathway.8
355064372022Knockdown of CDCA5 suppresses malignant progression of breast cancer cells by regulating PDS5A.3
355090672022TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5.22
356426722022Loss of cell division cycle‑associated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinoma.6
360044702022CDCA5 promotes the progression of breast cancer and serves as a potential prognostic biomarker.6
353734202022Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non-small cell lung cancer cells via p53-p21 signaling pathway.8
355064372022Knockdown of CDCA5 suppresses malignant progression of breast cancer cells by regulating PDS5A.3
355090672022TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5.22
356426722022Loss of cell division cycle‑associated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinoma.6

Citation

Dessen P

CDCA5 (cell division cycle associated 5)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51637/cdca5