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CDH12 (cadherin 12)

Identity

Alias_namescadherin 12
Alias_symbol (synonym)Br-cadherin
CDHB
Other alias
HGNC (Hugo) CDH12
LocusID (NCBI) 1010
Atlas_Id 40017
Location 5p14.3  [Link to chromosome band 5p14]
Location_base_pair Starts at 21750866 and ends at 22212769 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CDH12 (5p14.3) / HSPD1 (2q33.1)GSK3A (19q13.2) / CDH12 (5p14.3)NUDT3 (6p21.31) / CDH12 (5p14.3)
ZBTB8B (1p35.1) / CDH12 (5p14.3)NUDT3 6p21.31 / CDH12 5p14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDH12   1751
Cards
Entrez_Gene (NCBI)CDH12  1010  cadherin 12
AliasesCDHB
GeneCards (Weizmann)CDH12
Ensembl hg19 (Hinxton)ENSG00000154162 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154162 [Gene_View]  chr5:21750866-22212769 [Contig_View]  CDH12 [Vega]
ICGC DataPortalENSG00000154162
TCGA cBioPortalCDH12
AceView (NCBI)CDH12
Genatlas (Paris)CDH12
WikiGenes1010
SOURCE (Princeton)CDH12
Genetics Home Reference (NIH)CDH12
Genomic and cartography
GoldenPath hg38 (UCSC)CDH12  -     chr5:21750866-22212769 -  5p14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDH12  -     5p14.3   [Description]    (hg19-Feb_2009)
EnsemblCDH12 - 5p14.3 [CytoView hg19]  CDH12 - 5p14.3 [CytoView hg38]
Mapping of homologs : NCBICDH12 [Mapview hg19]  CDH12 [Mapview hg38]
OMIM600562   
Gene and transcription
Genbank (Entrez)AK092176 AK295123 AK314800 BC047608 EU832103
RefSeq transcript (Entrez)NM_001317227 NM_001317228 NM_004061
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDH12
Cluster EST : UnigeneHs.113684 [ NCBI ]
CGAP (NCI)Hs.113684
Alternative Splicing GalleryENSG00000154162
Gene ExpressionCDH12 [ NCBI-GEO ]   CDH12 [ EBI - ARRAY_EXPRESS ]   CDH12 [ SEEK ]   CDH12 [ MEM ]
Gene Expression Viewer (FireBrowse)CDH12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1010
GTEX Portal (Tissue expression)CDH12
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55289   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55289  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55289
Splice isoforms : SwissVarP55289
PhosPhoSitePlusP55289
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Catenin_binding_dom   
Domain families : Pfam (Sanger)Cadherin (PF00028)    Cadherin_C (PF01049)   
Domain families : Pfam (NCBI)pfam00028    pfam01049   
Domain families : Smart (EMBL)CA (SM00112)  
Conserved Domain (NCBI)CDH12
DMDM Disease mutations1010
Blocks (Seattle)CDH12
SuperfamilyP55289
Human Protein AtlasENSG00000154162
Peptide AtlasP55289
HPRD11081
IPIIPI00296942   IPI00975524   
Protein Interaction databases
DIP (DOE-UCLA)P55289
IntAct (EBI)P55289
FunCoupENSG00000154162
BioGRIDCDH12
STRING (EMBL)CDH12
ZODIACCDH12
Ontologies - Pathways
QuickGOP55289
Ontology : AmiGOcalcium ion binding  plasma membrane  homophilic cell adhesion via plasma membrane adhesion molecules  integral component of membrane  adherens junction organization  
Ontology : EGO-EBIcalcium ion binding  plasma membrane  homophilic cell adhesion via plasma membrane adhesion molecules  integral component of membrane  adherens junction organization  
NDEx NetworkCDH12
Atlas of Cancer Signalling NetworkCDH12
Wikipedia pathwaysCDH12
Orthology - Evolution
OrthoDB1010
GeneTree (enSembl)ENSG00000154162
Phylogenetic Trees/Animal Genes : TreeFamCDH12
HOVERGENP55289
HOGENOMP55289
Homologs : HomoloGeneCDH12
Homology/Alignments : Family Browser (UCSC)CDH12
Gene fusions - Rearrangements
Fusion : MitelmanNUDT3/CDH12 [6p21.31/5p14.3]  [t(5;6)(p14;p21)]  
Fusion: TCGANUDT3 6p21.31 CDH12 5p14.3 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDH12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDH12
dbVarCDH12
ClinVarCDH12
1000_GenomesCDH12 
Exome Variant ServerCDH12
ExAC (Exome Aggregation Consortium)CDH12 (select the gene name)
Genetic variants : HAPMAP1010
Genomic Variants (DGV)CDH12 [DGVbeta]
DECIPHERCDH12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDH12 
Mutations
ICGC Data PortalCDH12 
TCGA Data PortalCDH12 
Broad Tumor PortalCDH12
OASIS PortalCDH12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDH12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDH12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDH12
DgiDB (Drug Gene Interaction Database)CDH12
DoCM (Curated mutations)CDH12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDH12 (select a term)
intoGenCDH12
Cancer3DCDH12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600562   
Orphanet
MedgenCDH12
Genetic Testing Registry CDH12
NextProtP55289 [Medical]
TSGene1010
GENETestsCDH12
Target ValidationCDH12
Huge Navigator CDH12 [HugePedia]
snp3D : Map Gene to Disease1010
BioCentury BCIQCDH12
ClinGenCDH12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1010
Chemical/Pharm GKB GenePA26285
Clinical trialCDH12
Miscellaneous
canSAR (ICR)CDH12 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDH12
EVEXCDH12
GoPubMedCDH12
iHOPCDH12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:27:39 CEST 2017

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