CDH12 (cadherin 12)

2003-11-01 Affiliation

Identity

HGNC

CDH12

LOCATION

5p14.3

LOCUSID

1010

ALIAS

CDHB

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 1010
MIM: 600562
HGNC: 1751
Ensembl: ENSG00000154162

Variants:

dbSNP: 1010
ClinVar: 1010
TCGA: ENSG00000154162
COSMIC: CDH12

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000154162	ENST00000382254	P55289
ENSG00000154162	ENST00000504376	P55289
ENSG00000154162	ENST00000522262	P55289

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Cell-Cell communication	REACTOME	R-HSA-1500931
Cell junction organization	REACTOME	R-HSA-446728
Cell-cell junction organization	REACTOME	R-HSA-421270
Adherens junctions interactions	REACTOME	R-HSA-418990

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
19473719	2010	Identification of genes associated with non-small-cell lung cancer promotion and progression.	40
19567891	2009	Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.	38
20453000	2010	A Large-scale genetic association study of esophageal adenocarcinoma risk.	23
26762412	2016	Cadherin-12 enhances proliferation in colorectal cancer cells and increases progression by promoting EMT.	7
21573496	2011	CDH12 promotes the invasion of salivary adenoid cystic carcinoma.	6

Citation

Dessen P

CDH12 (cadherin 12)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40017/cdh12