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CDH15 (cadherin 15)

Identity

Alias_namesCDH3
CDH14
cadherin 15, M-cadherin (myotubule)
cadherin 15, type 1, M-cadherin (myotubule)
Other aliasCDHM
MCAD
MRD3
HGNC (Hugo) CDH15
LocusID (NCBI) 1013
Atlas_Id 40019
Location 16q24.3  [Link to chromosome band 16q24]
Location_base_pair Starts at 89171755 and ends at 89195492 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KIRREL3 (11q24.2) / CDH15 (16q24.3)SF3B3 (16q22.1) / CDH15 (16q24.3)SF3B3 16q22.1 / CDH15 16q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDH15   1754
Cards
Entrez_Gene (NCBI)CDH15  1013  cadherin 15
AliasesCDH14; CDH3; CDHM; MCAD; 
MRD3
GeneCards (Weizmann)CDH15
Ensembl hg19 (Hinxton)ENSG00000129910 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129910 [Gene_View]  chr16:89171755-89195492 [Contig_View]  CDH15 [Vega]
ICGC DataPortalENSG00000129910
TCGA cBioPortalCDH15
AceView (NCBI)CDH15
Genatlas (Paris)CDH15
WikiGenes1013
SOURCE (Princeton)CDH15
Genetics Home Reference (NIH)CDH15
Genomic and cartography
GoldenPath hg38 (UCSC)CDH15  -     chr16:89171755-89195492 +  16q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDH15  -     16q24.3   [Description]    (hg19-Feb_2009)
EnsemblCDH15 - 16q24.3 [CytoView hg19]  CDH15 - 16q24.3 [CytoView hg38]
Mapping of homologs : NCBICDH15 [Mapview hg19]  CDH15 [Mapview hg38]
OMIM114019   612580   
Gene and transcription
Genbank (Entrez)AK308596 AK308631 AW452260 BC008951 D83542
RefSeq transcript (Entrez)NM_004933
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDH15
Cluster EST : UnigeneHs.148090 [ NCBI ]
CGAP (NCI)Hs.148090
Alternative Splicing GalleryENSG00000129910
Gene ExpressionCDH15 [ NCBI-GEO ]   CDH15 [ EBI - ARRAY_EXPRESS ]   CDH15 [ SEEK ]   CDH15 [ MEM ]
Gene Expression Viewer (FireBrowse)CDH15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1013
GTEX Portal (Tissue expression)CDH15
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55291   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55291  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55291
Splice isoforms : SwissVarP55291
PhosPhoSitePlusP55291
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Catenin_binding_dom   
Domain families : Pfam (Sanger)Cadherin (PF00028)    Cadherin_C (PF01049)   
Domain families : Pfam (NCBI)pfam00028    pfam01049   
Domain families : Smart (EMBL)CA (SM00112)  
Conserved Domain (NCBI)CDH15
DMDM Disease mutations1013
Blocks (Seattle)CDH15
SuperfamilyP55291
Human Protein AtlasENSG00000129910
Peptide AtlasP55291
HPRD00225
IPIIPI00024048   
Protein Interaction databases
DIP (DOE-UCLA)P55291
IntAct (EBI)P55291
FunCoupENSG00000129910
BioGRIDCDH15
STRING (EMBL)CDH15
ZODIACCDH15
Ontologies - Pathways
QuickGOP55291
Ontology : AmiGOcalcium ion binding  protein binding  plasma membrane  caveola  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  integral component of membrane  neuromuscular junction  adherens junction organization  positive regulation of muscle cell differentiation  extracellular exosome  
Ontology : EGO-EBIcalcium ion binding  protein binding  plasma membrane  caveola  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  integral component of membrane  neuromuscular junction  adherens junction organization  positive regulation of muscle cell differentiation  extracellular exosome  
Pathways : KEGGCell adhesion molecules (CAMs)   
NDEx NetworkCDH15
Atlas of Cancer Signalling NetworkCDH15
Wikipedia pathwaysCDH15
Orthology - Evolution
OrthoDB1013
GeneTree (enSembl)ENSG00000129910
Phylogenetic Trees/Animal Genes : TreeFamCDH15
HOVERGENP55291
HOGENOMP55291
Homologs : HomoloGeneCDH15
Homology/Alignments : Family Browser (UCSC)CDH15
Gene fusions - Rearrangements
Fusion : MitelmanSF3B3/CDH15 [16q22.1/16q24.3]  [t(16;16)(q22;q24)]  
Fusion: TCGASF3B3 16q22.1 CDH15 16q24.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDH15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDH15
dbVarCDH15
ClinVarCDH15
1000_GenomesCDH15 
Exome Variant ServerCDH15
ExAC (Exome Aggregation Consortium)CDH15 (select the gene name)
Genetic variants : HAPMAP1013
Genomic Variants (DGV)CDH15 [DGVbeta]
DECIPHERCDH15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDH15 
Mutations
ICGC Data PortalCDH15 
TCGA Data PortalCDH15 
Broad Tumor PortalCDH15
OASIS PortalCDH15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDH15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDH15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDH15
DgiDB (Drug Gene Interaction Database)CDH15
DoCM (Curated mutations)CDH15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDH15 (select a term)
intoGenCDH15
Cancer3DCDH15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114019    612580   
Orphanet18028   
MedgenCDH15
Genetic Testing Registry CDH15
NextProtP55291 [Medical]
TSGene1013
GENETestsCDH15
Target ValidationCDH15
Huge Navigator CDH15 [HugePedia]
snp3D : Map Gene to Disease1013
BioCentury BCIQCDH15
ClinGenCDH15 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1013
Chemical/Pharm GKB GenePA26288
Clinical trialCDH15
Miscellaneous
canSAR (ICR)CDH15 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDH15
EVEXCDH15
GoPubMedCDH15
iHOPCDH15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:01:35 CEST 2017

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