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CDH15 (cadherin 15)

Identity

Alias (NCBI)CDH14
CDH3
CDHM
MCAD
MRD3
HGNC (Hugo) CDH15
HGNC Previous nameCDH3
 CDH14
HGNC Previous namecadherin 15, M-cadherin (myotubule)
 cadherin 15, type 1, M-cadherin (myotubule)
LocusID (NCBI) 1013
Atlas_Id 40019
Location 16q24.3  [Link to chromosome band 16q24]
Location_base_pair Starts at 89171748 and ends at 89195492 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KIRREL3 (11q24.2)::CDH15 (16q24.3)SF3B3 (16q22.1)::CDH15 (16q24.3)SF3B3 16q22.1::CDH15 16q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CDH15   1754
Cards
Entrez_Gene (NCBI)CDH15    cadherin 15
AliasesCDH14; CDH3; CDHM; MCAD; 
MRD3
GeneCards (Weizmann)CDH15
Ensembl hg19 (Hinxton)ENSG00000129910 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129910 [Gene_View]  ENSG00000129910 [Sequence]  chr16:89171748-89195492 [Contig_View]  CDH15 [Vega]
ICGC DataPortalENSG00000129910
TCGA cBioPortalCDH15
AceView (NCBI)CDH15
Genatlas (Paris)CDH15
SOURCE (Princeton)CDH15
Genetics Home Reference (NIH)CDH15
Genomic and cartography
GoldenPath hg38 (UCSC)CDH15  -     chr16:89171748-89195492 +  16q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDH15  -     16q24.3   [Description]    (hg19-Feb_2009)
GoldenPathCDH15 - 16q24.3 [CytoView hg19]  CDH15 - 16q24.3 [CytoView hg38]
ImmunoBaseENSG00000129910
Genome Data Viewer NCBICDH15 [Mapview hg19]  
OMIM114019   612580   
Gene and transcription
Genbank (Entrez)AK308596 AK308631 AW452260 BC008951 D83542
RefSeq transcript (Entrez)NM_004933
Consensus coding sequences : CCDS (NCBI)CDH15
Gene ExpressionCDH15 [ NCBI-GEO ]   CDH15 [ EBI - ARRAY_EXPRESS ]   CDH15 [ SEEK ]   CDH15 [ MEM ]
Gene Expression Viewer (FireBrowse)CDH15 [ Firebrowse - Broad ]
GenevisibleExpression of CDH15 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1013
GTEX Portal (Tissue expression)CDH15
Human Protein AtlasENSG00000129910-CDH15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55291   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55291  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55291
PhosPhoSitePlusP55291
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like_dom    Cadherin-like_sf    Cadherin_CS    Cadherin_cytoplasmic-dom    Catenin-bd_sf   
Domain families : Pfam (Sanger)Cadherin (PF00028)    Cadherin_C (PF01049)   
Domain families : Pfam (NCBI)pfam00028    pfam01049   
Domain families : Smart (EMBL)CA (SM00112)  
Conserved Domain (NCBI)CDH15
SuperfamilyP55291
AlphaFold pdb e-kbP55291   
Human Protein Atlas [tissue]ENSG00000129910-CDH15 [tissue]
HPRD00225
Protein Interaction databases
DIP (DOE-UCLA)P55291
IntAct (EBI)P55291
BioGRIDCDH15
STRING (EMBL)CDH15
ZODIACCDH15
Ontologies - Pathways
QuickGOP55291
Ontology : AmiGOcalcium ion binding  protein binding  Golgi apparatus  plasma membrane  plasma membrane  caveola  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  integral component of membrane  catenin complex  neuromuscular junction  cadherin binding  extracellular exosome  cell-cell adhesion via plasma-membrane adhesion molecules  
Ontology : EGO-EBIcalcium ion binding  protein binding  Golgi apparatus  plasma membrane  plasma membrane  caveola  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  integral component of membrane  catenin complex  neuromuscular junction  cadherin binding  extracellular exosome  cell-cell adhesion via plasma-membrane adhesion molecules  
Pathways : KEGGKEGG_CELL_ADHESION_MOLECULES_CAMS   
NDEx NetworkCDH15
Atlas of Cancer Signalling NetworkCDH15
Wikipedia pathwaysCDH15
Orthology - Evolution
OrthoDB1013
GeneTree (enSembl)ENSG00000129910
Phylogenetic Trees/Animal Genes : TreeFamCDH15
Homologs : HomoloGeneCDH15
Homology/Alignments : Family Browser (UCSC)CDH15
Gene fusions - Rearrangements
Fusion : MitelmanSF3B3::CDH15 [16q22.1/16q24.3]  
Fusion : QuiverCDH15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDH15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDH15
dbVarCDH15
ClinVarCDH15
MonarchCDH15
1000_GenomesCDH15 
Exome Variant ServerCDH15
GNOMAD BrowserENSG00000129910
Varsome BrowserCDH15
ACMGCDH15 variants
VarityP55291
Genomic Variants (DGV)CDH15 [DGVbeta]
DECIPHERCDH15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDH15 
Mutations
ICGC Data PortalCDH15 
TCGA Data PortalCDH15 
Broad Tumor PortalCDH15
OASIS PortalCDH15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDH15  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCDH15
Mutations and Diseases : HGMDCDH15
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCDH15
DgiDB (Drug Gene Interaction Database)CDH15
DoCM (Curated mutations)CDH15
CIViC (Clinical Interpretations of Variants in Cancer)CDH15
Cancer3DCDH15
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114019    612580   
Orphanet18028   
DisGeNETCDH15
MedgenCDH15
Genetic Testing Registry CDH15
NextProtP55291 [Medical]
GENETestsCDH15
Target ValidationCDH15
Huge Navigator CDH15 [HugePedia]
ClinGenCDH15 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeCDH15
Protein Interactions : CTDCDH15
Pharm GKB GenePA26288
PharosP55291
Clinical trialCDH15
Miscellaneous
canSAR (ICR)CDH15
HarmonizomeCDH15
ARCHS4CDH15
DataMed IndexCDH15
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCDH15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:26:42 CET 2022

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