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CDH6 (cadherin 6)

Identity

Alias_namescadherin 6
Other aliasCAD6
KCAD
HGNC (Hugo) CDH6
LocusID (NCBI) 1004
Atlas_Id 40028
Location 5p13.3  [Link to chromosome band 5p13]
Location_base_pair Starts at 31193655 and ends at 31329146 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NUP133 (1q42.13) / CDH6 (5p13.3)NUP133 1q42.13 / CDH6 5p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDH6   1765
Cards
Entrez_Gene (NCBI)CDH6  1004  cadherin 6
AliasesCAD6; KCAD
GeneCards (Weizmann)CDH6
Ensembl hg19 (Hinxton)ENSG00000113361 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113361 [Gene_View]  chr5:31193655-31329146 [Contig_View]  CDH6 [Vega]
ICGC DataPortalENSG00000113361
TCGA cBioPortalCDH6
AceView (NCBI)CDH6
Genatlas (Paris)CDH6
WikiGenes1004
SOURCE (Princeton)CDH6
Genetics Home Reference (NIH)CDH6
Genomic and cartography
GoldenPath hg38 (UCSC)CDH6  -     chr5:31193655-31329146 +  5p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDH6  -     5p13.3   [Description]    (hg19-Feb_2009)
EnsemblCDH6 - 5p13.3 [CytoView hg19]  CDH6 - 5p13.3 [CytoView hg38]
Mapping of homologs : NCBICDH6 [Mapview hg19]  CDH6 [Mapview hg38]
OMIM603007   
Gene and transcription
Genbank (Entrez)AK024238 AK291290 AL049227 AU130185 BC000019
RefSeq transcript (Entrez)NM_004932
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDH6
Cluster EST : UnigeneHs.171054 [ NCBI ]
CGAP (NCI)Hs.171054
Alternative Splicing GalleryENSG00000113361
Gene ExpressionCDH6 [ NCBI-GEO ]   CDH6 [ EBI - ARRAY_EXPRESS ]   CDH6 [ SEEK ]   CDH6 [ MEM ]
Gene Expression Viewer (FireBrowse)CDH6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1004
GTEX Portal (Tissue expression)CDH6
Human Protein AtlasENSG00000113361-CDH6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55285   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55285  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55285
Splice isoforms : SwissVarP55285
PhosPhoSitePlusP55285
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Catenin_binding_dom   
Domain families : Pfam (Sanger)Cadherin (PF00028)    Cadherin_C (PF01049)   
Domain families : Pfam (NCBI)pfam00028    pfam01049   
Domain families : Smart (EMBL)CA (SM00112)  
Conserved Domain (NCBI)CDH6
DMDM Disease mutations1004
Blocks (Seattle)CDH6
SuperfamilyP55285
Human Protein Atlas [tissue]ENSG00000113361-CDH6 [tissue]
Peptide AtlasP55285
HPRD04305
IPIIPI00024035   IPI00217314   
Protein Interaction databases
DIP (DOE-UCLA)P55285
IntAct (EBI)P55285
FunCoupENSG00000113361
BioGRIDCDH6
STRING (EMBL)CDH6
ZODIACCDH6
Ontologies - Pathways
QuickGOP55285
Ontology : AmiGOcalcium ion binding  plasma membrane  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  Notch signaling pathway  integral component of membrane  adherens junction organization  extracellular exosome  
Ontology : EGO-EBIcalcium ion binding  plasma membrane  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  Notch signaling pathway  integral component of membrane  adherens junction organization  extracellular exosome  
NDEx NetworkCDH6
Atlas of Cancer Signalling NetworkCDH6
Wikipedia pathwaysCDH6
Orthology - Evolution
OrthoDB1004
GeneTree (enSembl)ENSG00000113361
Phylogenetic Trees/Animal Genes : TreeFamCDH6
HOVERGENP55285
HOGENOMP55285
Homologs : HomoloGeneCDH6
Homology/Alignments : Family Browser (UCSC)CDH6
Gene fusions - Rearrangements
Fusion : MitelmanNUP133/CDH6 [1q42.13/5p13.3]  [t(1;5)(q42;p13)]  
Fusion: TCGA_MDACCNUP133 1q42.13 CDH6 5p13.3 BLCA
Tumor Fusion PortalCDH6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDH6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDH6
dbVarCDH6
ClinVarCDH6
1000_GenomesCDH6 
Exome Variant ServerCDH6
ExAC (Exome Aggregation Consortium)ENSG00000113361
GNOMAD BrowserENSG00000113361
Genetic variants : HAPMAP1004
Genomic Variants (DGV)CDH6 [DGVbeta]
DECIPHERCDH6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDH6 
Mutations
ICGC Data PortalCDH6 
TCGA Data PortalCDH6 
Broad Tumor PortalCDH6
OASIS PortalCDH6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDH6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDH6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDH6
DgiDB (Drug Gene Interaction Database)CDH6
DoCM (Curated mutations)CDH6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDH6 (select a term)
intoGenCDH6
Cancer3DCDH6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603007   
Orphanet
DisGeNETCDH6
MedgenCDH6
Genetic Testing Registry CDH6
NextProtP55285 [Medical]
TSGene1004
GENETestsCDH6
Target ValidationCDH6
Huge Navigator CDH6 [HugePedia]
snp3D : Map Gene to Disease1004
BioCentury BCIQCDH6
ClinGenCDH6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1004
Chemical/Pharm GKB GenePA26302
Clinical trialCDH6
Miscellaneous
canSAR (ICR)CDH6 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDH6
EVEXCDH6
GoPubMedCDH6
iHOPCDH6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:07:01 CET 2017

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