Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CDH8 (cadherin 8)

Identity

Alias_namescadherin 8
Other aliasNbla04261
HGNC (Hugo) CDH8
LocusID (NCBI) 1006
Atlas_Id 45620
Location 16q21  [Link to chromosome band 16q21]
Location_base_pair Starts at 61685915 and ends at 62070739 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
C12orf29 (12q21.32) / CDH8 (16q21)PRKCA (17q24.2) / CDH8 (16q21)VAC14 (16q22.1) / CDH8 (16q21)
PRKCA 17q24.2 / CDH8 16q21VAC14 16q22.1 / CDH8 16q21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDH8   1767
Cards
Entrez_Gene (NCBI)CDH8  1006  cadherin 8
AliasesNbla04261
GeneCards (Weizmann)CDH8
Ensembl hg19 (Hinxton)ENSG00000150394 [Gene_View]  chr16:61685915-62070739 [Contig_View]  CDH8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000150394 [Gene_View]  chr16:61685915-62070739 [Contig_View]  CDH8 [Vega]
ICGC DataPortalENSG00000150394
TCGA cBioPortalCDH8
AceView (NCBI)CDH8
Genatlas (Paris)CDH8
WikiGenes1006
SOURCE (Princeton)CDH8
Genetics Home Reference (NIH)CDH8
Genomic and cartography
GoldenPath hg19 (UCSC)CDH8  -     chr16:61685915-62070739 -  16q21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CDH8  -     16q21   [Description]    (hg38-Dec_2013)
EnsemblCDH8 - 16q21 [CytoView hg19]  CDH8 - 16q21 [CytoView hg38]
Mapping of homologs : NCBICDH8 [Mapview hg19]  CDH8 [Mapview hg38]
OMIM603008   
Gene and transcription
Genbank (Entrez)AB035305 AB074170 AK124734 BC113416 HQ258504
RefSeq transcript (Entrez)NM_001796
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)CDH8
Cluster EST : UnigeneHs.368322 [ NCBI ]
CGAP (NCI)Hs.368322
Alternative Splicing GalleryENSG00000150394
Gene ExpressionCDH8 [ NCBI-GEO ]   CDH8 [ EBI - ARRAY_EXPRESS ]   CDH8 [ SEEK ]   CDH8 [ MEM ]
Gene Expression Viewer (FireBrowse)CDH8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1006
GTEX Portal (Tissue expression)CDH8
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55286   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55286  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55286
Splice isoforms : SwissVarP55286
PhosPhoSitePlusP55286
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Catenin_binding_dom   
Domain families : Pfam (Sanger)Cadherin (PF00028)    Cadherin_C (PF01049)   
Domain families : Pfam (NCBI)pfam00028    pfam01049   
Domain families : Smart (EMBL)CA (SM00112)  
Conserved Domain (NCBI)CDH8
DMDM Disease mutations1006
Blocks (Seattle)CDH8
SuperfamilyP55286
Human Protein AtlasENSG00000150394
Peptide AtlasP55286
HPRD04306
IPIIPI00024036   IPI00871825   IPI00654576   
Protein Interaction databases
DIP (DOE-UCLA)P55286
IntAct (EBI)P55286
FunCoupENSG00000150394
BioGRIDCDH8
STRING (EMBL)CDH8
ZODIACCDH8
Ontologies - Pathways
QuickGOP55286
Ontology : AmiGOcalcium ion binding  plasma membrane  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  response to cold  integral component of membrane  adherens junction organization  synaptic transmission, glutamatergic  synaptic cleft  axon terminus  
Ontology : EGO-EBIcalcium ion binding  plasma membrane  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  response to cold  integral component of membrane  adherens junction organization  synaptic transmission, glutamatergic  synaptic cleft  axon terminus  
NDEx NetworkCDH8
Atlas of Cancer Signalling NetworkCDH8
Wikipedia pathwaysCDH8
Orthology - Evolution
OrthoDB1006
GeneTree (enSembl)ENSG00000150394
Phylogenetic Trees/Animal Genes : TreeFamCDH8
HOVERGENP55286
HOGENOMP55286
Homologs : HomoloGeneCDH8
Homology/Alignments : Family Browser (UCSC)CDH8
Gene fusions - Rearrangements
Fusion : MitelmanPRKCA/CDH8 [17q24.2/16q21]  [t(16;17)(q21;q24)]  
Fusion : MitelmanVAC14/CDH8 [16q22.1/16q21]  [t(16;16)(q21;q22)]  
Fusion: TCGAPRKCA 17q24.2 CDH8 16q21 BRCA
Fusion: TCGAVAC14 16q22.1 CDH8 16q21 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDH8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDH8
dbVarCDH8
ClinVarCDH8
1000_GenomesCDH8 
Exome Variant ServerCDH8
ExAC (Exome Aggregation Consortium)CDH8 (select the gene name)
Genetic variants : HAPMAP1006
Genomic Variants (DGV)CDH8 [DGVbeta]
DECIPHER (Syndromes)16:61685915-62070739  ENSG00000150394
CONAN: Copy Number AnalysisCDH8 
Mutations
ICGC Data PortalCDH8 
TCGA Data PortalCDH8 
Broad Tumor PortalCDH8
OASIS PortalCDH8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDH8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDH8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDH8
DgiDB (Drug Gene Interaction Database)CDH8
DoCM (Curated mutations)CDH8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDH8 (select a term)
intoGenCDH8
Cancer3DCDH8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603008   
Orphanet
MedgenCDH8
Genetic Testing Registry CDH8
NextProtP55286 [Medical]
TSGene1006
GENETestsCDH8
Huge Navigator CDH8 [HugePedia]
snp3D : Map Gene to Disease1006
BioCentury BCIQCDH8
ClinGenCDH8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1006
Chemical/Pharm GKB GenePA26304
Clinical trialCDH8
Miscellaneous
canSAR (ICR)CDH8 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDH8
EVEXCDH8
GoPubMedCDH8
iHOPCDH8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:55:54 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.