Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CDHR2 (cadherin related family member 2)

Identity

Alias_namesPCDH24
protocadherin 24
cadherin-related family member 2
Alias_symbol (synonym)PC-LKC
FLJ20124
FLJ20383
PCLKC
Other alias
HGNC (Hugo) CDHR2
LocusID (NCBI) 54825
Atlas_Id 41652
Location 5q35.2  [Link to chromosome band 5q35]
Location_base_pair Starts at 176542511 and ends at 176595768 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CLPTM1L (5p15.33) / CDHR2 (5q35.2)WDYHV1 (8q24.13) / CDHR2 (5q35.2)CLPTM1L 5p15.33 / CDHR2 5q35.2
WDYHV1 8q24.13 / CDHR2 5q35.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDHR2   18231
Cards
Entrez_Gene (NCBI)CDHR2  54825  cadherin related family member 2
AliasesPCDH24; PCLKC
GeneCards (Weizmann)CDHR2
Ensembl hg19 (Hinxton)ENSG00000074276 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000074276 [Gene_View]  chr5:176542511-176595768 [Contig_View]  CDHR2 [Vega]
ICGC DataPortalENSG00000074276
TCGA cBioPortalCDHR2
AceView (NCBI)CDHR2
Genatlas (Paris)CDHR2
WikiGenes54825
SOURCE (Princeton)CDHR2
Genetics Home Reference (NIH)CDHR2
Genomic and cartography
GoldenPath hg38 (UCSC)CDHR2  -     chr5:176542511-176595768 +  5q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDHR2  -     5q35.2   [Description]    (hg19-Feb_2009)
EnsemblCDHR2 - 5q35.2 [CytoView hg19]  CDHR2 - 5q35.2 [CytoView hg38]
Mapping of homologs : NCBICDHR2 [Mapview hg19]  CDHR2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA130780 AB047004 AK000131 AK000390 AK225217
RefSeq transcript (Entrez)NM_001171976 NM_017675
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDHR2
Cluster EST : UnigeneHs.4205 [ NCBI ]
CGAP (NCI)Hs.4205
Alternative Splicing GalleryENSG00000074276
Gene ExpressionCDHR2 [ NCBI-GEO ]   CDHR2 [ EBI - ARRAY_EXPRESS ]   CDHR2 [ SEEK ]   CDHR2 [ MEM ]
Gene Expression Viewer (FireBrowse)CDHR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54825
GTEX Portal (Tissue expression)CDHR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYE9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYE9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYE9
Splice isoforms : SwissVarQ9BYE9
PhosPhoSitePlusQ9BYE9
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    CDHR2   
Domain families : Pfam (Sanger)Cadherin (PF00028)   
Domain families : Pfam (NCBI)pfam00028   
Domain families : Smart (EMBL)CA (SM00112)  
Conserved Domain (NCBI)CDHR2
DMDM Disease mutations54825
Blocks (Seattle)CDHR2
PDB (SRS)5CZR   
PDB (PDBSum)5CZR   
PDB (IMB)5CZR   
PDB (RSDB)5CZR   
Structural Biology KnowledgeBase5CZR   
SCOP (Structural Classification of Proteins)5CZR   
CATH (Classification of proteins structures)5CZR   
SuperfamilyQ9BYE9
Human Protein AtlasENSG00000074276
Peptide AtlasQ9BYE9
HPRD15103
IPIIPI00307446   IPI00967364   
Protein Interaction databases
DIP (DOE-UCLA)Q9BYE9
IntAct (EBI)Q9BYE9
FunCoupENSG00000074276
BioGRIDCDHR2
STRING (EMBL)CDHR2
ZODIACCDHR2
Ontologies - Pathways
QuickGOQ9BYE9
Ontology : AmiGOcalcium ion binding  protein binding  brush border  homophilic cell adhesion via plasma membrane adhesion molecules  apical plasma membrane  cell junction  epithelial cell differentiation  brush border membrane  microvillus membrane  regulation of microvillus length  spanning component of plasma membrane  cell-cell adhesion mediated by cadherin  cell adhesion molecule binding  negative regulation of cell growth involved in contact inhibition  extracellular exosome  intermicrovillar adhesion  
Ontology : EGO-EBIcalcium ion binding  protein binding  brush border  homophilic cell adhesion via plasma membrane adhesion molecules  apical plasma membrane  cell junction  epithelial cell differentiation  brush border membrane  microvillus membrane  regulation of microvillus length  spanning component of plasma membrane  cell-cell adhesion mediated by cadherin  cell adhesion molecule binding  negative regulation of cell growth involved in contact inhibition  extracellular exosome  intermicrovillar adhesion  
NDEx NetworkCDHR2
Atlas of Cancer Signalling NetworkCDHR2
Wikipedia pathwaysCDHR2
Orthology - Evolution
OrthoDB54825
GeneTree (enSembl)ENSG00000074276
Phylogenetic Trees/Animal Genes : TreeFamCDHR2
HOVERGENQ9BYE9
HOGENOMQ9BYE9
Homologs : HomoloGeneCDHR2
Homology/Alignments : Family Browser (UCSC)CDHR2
Gene fusions - Rearrangements
Fusion : MitelmanCLPTM1L/CDHR2 [5p15.33/5q35.2]  [t(5;5)(p15;q35)]  
Fusion : MitelmanWDYHV1/CDHR2 [8q24.13/5q35.2]  [t(5;8)(q35;q24)]  
Fusion: TCGACLPTM1L 5p15.33 CDHR2 5q35.2 KIRC
Fusion: TCGAWDYHV1 8q24.13 CDHR2 5q35.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDHR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDHR2
dbVarCDHR2
ClinVarCDHR2
1000_GenomesCDHR2 
Exome Variant ServerCDHR2
ExAC (Exome Aggregation Consortium)CDHR2 (select the gene name)
Genetic variants : HAPMAP54825
Genomic Variants (DGV)CDHR2 [DGVbeta]
DECIPHERCDHR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDHR2 
Mutations
ICGC Data PortalCDHR2 
TCGA Data PortalCDHR2 
Broad Tumor PortalCDHR2
OASIS PortalCDHR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDHR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDHR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDHR2
DgiDB (Drug Gene Interaction Database)CDHR2
DoCM (Curated mutations)CDHR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDHR2 (select a term)
intoGenCDHR2
Cancer3DCDHR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCDHR2
Genetic Testing Registry CDHR2
NextProtQ9BYE9 [Medical]
TSGene54825
GENETestsCDHR2
Huge Navigator CDHR2 [HugePedia]
snp3D : Map Gene to Disease54825
BioCentury BCIQCDHR2
ClinGenCDHR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54825
Chemical/Pharm GKB GenePA165660231
Clinical trialCDHR2
Miscellaneous
canSAR (ICR)CDHR2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDHR2
EVEXCDHR2
GoPubMedCDHR2
iHOPCDHR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:09:53 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.