Identity
HGNC
LOCATION
1p36.33
LOCUSID
ALIAS
CDC2L2,CDC2L3,CDK11-p110,CDK11-p46,CDK11-p58,PITSLRE,p58GTA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 728642
MIM: 116951
HGNC: 1730
Ensembl: ENSG00000008128
Variants:
dbSNP: 728642
ClinVar: 728642
TCGA: ENSG00000008128
COSMIC: CDK11A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33309857 | 2021 | Galactosyltransferase B4GALT1 confers chemoresistance in pancreatic ductal adenocarcinomas by upregulating N-linked glycosylation of CDK11(p110). | 15 |
| 33309857 | 2021 | Galactosyltransferase B4GALT1 confers chemoresistance in pancreatic ductal adenocarcinomas by upregulating N-linked glycosylation of CDK11(p110). | 15 |
| 30722725 | 2019 | CDK11(p110) plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target. | 9 |
| 30722725 | 2019 | CDK11(p110) plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target. | 9 |
| 27049727 | 2016 | The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer. | 29 |
| 27049727 | 2016 | The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer. | 29 |
| 20508983 | 2011 | Centrosome-related genes, genetic variation, and risk of breast cancer. | 21 |
| 20508983 | 2011 | Centrosome-related genes, genetic variation, and risk of breast cancer. | 21 |
| 19122208 | 2009 | Repression of estrogen receptor alpha by CDK11p58 through promoting its ubiquitin-proteasome degradation. | 13 |
| 19245811 | 2009 | Phosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosis. | 33 |
| 19520772 | 2009 | CDK11p58 phosphorylation of PAK1 Ser174 promotes DLC2 binding and roles on cell cycle progression. | 8 |
| 19122208 | 2009 | Repression of estrogen receptor alpha by CDK11p58 through promoting its ubiquitin-proteasome degradation. | 13 |
| 19245811 | 2009 | Phosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosis. | 33 |
| 19520772 | 2009 | CDK11p58 phosphorylation of PAK1 Ser174 promotes DLC2 binding and roles on cell cycle progression. | 8 |
| 17177267 | 2007 | Genetic variations of the CDC2L2 gene are associated with type 2 diabetes in a Han Chinese cohort. | 1 |
Citation
Dessen P
CDK11A (cyclin dependent kinase 11A)
Atlas Genet Cytogenet Oncol Haematol. 2010-01-01
Online version: http://atlasgeneticsoncology.org/gene/51286/cdk11a
