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CDK15 (cyclin dependent kinase 15)

Identity

Alias_namesALS2CR7
PFTK2
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 7
PFTAIRE protein kinase 2
Alias_symbol (synonym)PFTAIRE2
Other alias
HGNC (Hugo) CDK15
LocusID (NCBI) 65061
Atlas_Id 43117
Location 2q33.1  [Link to chromosome band 2q33]
Location_base_pair Starts at 201806579 and ends at 201895550 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CDK15 (2q33.1) / FOLR2 (11q13.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDK15   14434
Cards
Entrez_Gene (NCBI)CDK15  65061  cyclin dependent kinase 15
AliasesALS2CR7; PFTAIRE2; PFTK2
GeneCards (Weizmann)CDK15
Ensembl hg19 (Hinxton)ENSG00000138395 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138395 [Gene_View]  chr2:201806579-201895550 [Contig_View]  CDK15 [Vega]
ICGC DataPortalENSG00000138395
TCGA cBioPortalCDK15
AceView (NCBI)CDK15
Genatlas (Paris)CDK15
WikiGenes65061
SOURCE (Princeton)CDK15
Genetics Home Reference (NIH)CDK15
Genomic and cartography
GoldenPath hg38 (UCSC)CDK15  -     chr2:201806579-201895550 +  2q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDK15  -     2q33.1   [Description]    (hg19-Feb_2009)
EnsemblCDK15 - 2q33.1 [CytoView hg19]  CDK15 - 2q33.1 [CytoView hg38]
Mapping of homologs : NCBICDK15 [Mapview hg19]  CDK15 [Mapview hg38]
OMIM616147   
Gene and transcription
Genbank (Entrez)AB053308 AK091710 AK131512 AK292434 AK310050
RefSeq transcript (Entrez)NM_001261435 NM_001261436 NM_139158
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDK15
Cluster EST : UnigeneHs.348711 [ NCBI ]
CGAP (NCI)Hs.348711
Alternative Splicing GalleryENSG00000138395
Gene ExpressionCDK15 [ NCBI-GEO ]   CDK15 [ EBI - ARRAY_EXPRESS ]   CDK15 [ SEEK ]   CDK15 [ MEM ]
Gene Expression Viewer (FireBrowse)CDK15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65061
GTEX Portal (Tissue expression)CDK15
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96Q40   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96Q40  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96Q40
Splice isoforms : SwissVarQ96Q40
PhosPhoSitePlusQ96Q40
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)CDK15
DMDM Disease mutations65061
Blocks (Seattle)CDK15
SuperfamilyQ96Q40
Human Protein AtlasENSG00000138395
Peptide AtlasQ96Q40
HPRD12449
IPIIPI00044678   IPI00442058   IPI00829793   IPI00955397   IPI00916742   
Protein Interaction databases
DIP (DOE-UCLA)Q96Q40
IntAct (EBI)Q96Q40
FunCoupENSG00000138395
BioGRIDCDK15
STRING (EMBL)CDK15
ZODIACCDK15
Ontologies - Pathways
QuickGOQ96Q40
Ontology : AmiGOprotein serine/threonine kinase activity  cyclin-dependent protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytosol  protein phosphorylation  cyclin binding  metal ion binding  regulation of cell cycle  
Ontology : EGO-EBIprotein serine/threonine kinase activity  cyclin-dependent protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytosol  protein phosphorylation  cyclin binding  metal ion binding  regulation of cell cycle  
NDEx NetworkCDK15
Atlas of Cancer Signalling NetworkCDK15
Wikipedia pathwaysCDK15
Orthology - Evolution
OrthoDB65061
GeneTree (enSembl)ENSG00000138395
Phylogenetic Trees/Animal Genes : TreeFamCDK15
HOVERGENQ96Q40
HOGENOMQ96Q40
Homologs : HomoloGeneCDK15
Homology/Alignments : Family Browser (UCSC)CDK15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDK15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDK15
dbVarCDK15
ClinVarCDK15
1000_GenomesCDK15 
Exome Variant ServerCDK15
ExAC (Exome Aggregation Consortium)CDK15 (select the gene name)
Genetic variants : HAPMAP65061
Genomic Variants (DGV)CDK15 [DGVbeta]
DECIPHERCDK15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDK15 
Mutations
ICGC Data PortalCDK15 
TCGA Data PortalCDK15 
Broad Tumor PortalCDK15
OASIS PortalCDK15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDK15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDK15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDK15
DgiDB (Drug Gene Interaction Database)CDK15
DoCM (Curated mutations)CDK15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDK15 (select a term)
intoGenCDK15
Cancer3DCDK15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616147   
Orphanet
MedgenCDK15
Genetic Testing Registry CDK15
NextProtQ96Q40 [Medical]
TSGene65061
GENETestsCDK15
Huge Navigator CDK15 [HugePedia]
snp3D : Map Gene to Disease65061
BioCentury BCIQCDK15
ClinGenCDK15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65061
Chemical/Pharm GKB GenePA165696414
Clinical trialCDK15
Miscellaneous
canSAR (ICR)CDK15 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDK15
EVEXCDK15
GoPubMedCDK15
iHOPCDK15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:09:56 CEST 2017

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