Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CDK17 (cyclin dependent kinase 17)

Identity

Alias_namesPCTK2
PCTAIRE protein kinase 2
Alias_symbol (synonym)PCTAIRE2
Other alias
HGNC (Hugo) CDK17
LocusID (NCBI) 5128
Atlas_Id 43397
Location 12q23.1  [Link to chromosome band 12q23]
Location_base_pair Starts at 96278261 and ends at 96400588 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CAMTA1 (1p36.31) / CDK17 (12q23.1)CDK17 (12q23.1) / ADGRG6 (6q24.1)CDK17 (12q23.1) / SEPT7 (7p14.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDK17   8750
Cards
Entrez_Gene (NCBI)CDK17  5128  cyclin dependent kinase 17
AliasesPCTAIRE2; PCTK2
GeneCards (Weizmann)CDK17
Ensembl hg19 (Hinxton)ENSG00000059758 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000059758 [Gene_View]  chr12:96278261-96400588 [Contig_View]  CDK17 [Vega]
ICGC DataPortalENSG00000059758
TCGA cBioPortalCDK17
AceView (NCBI)CDK17
Genatlas (Paris)CDK17
WikiGenes5128
SOURCE (Princeton)CDK17
Genetics Home Reference (NIH)CDK17
Genomic and cartography
GoldenPath hg38 (UCSC)CDK17  -     chr12:96278261-96400588 -  12q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDK17  -     12q23.1   [Description]    (hg19-Feb_2009)
EnsemblCDK17 - 12q23.1 [CytoView hg19]  CDK17 - 12q23.1 [CytoView hg38]
Mapping of homologs : NCBICDK17 [Mapview hg19]  CDK17 [Mapview hg38]
OMIM603440   
Gene and transcription
Genbank (Entrez)AF086067 AK290011 AK294698 AK315214 BC033005
RefSeq transcript (Entrez)NM_001170464 NM_002595
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDK17
Cluster EST : UnigeneHs.506415 [ NCBI ]
CGAP (NCI)Hs.506415
Alternative Splicing GalleryENSG00000059758
Gene ExpressionCDK17 [ NCBI-GEO ]   CDK17 [ EBI - ARRAY_EXPRESS ]   CDK17 [ SEEK ]   CDK17 [ MEM ]
Gene Expression Viewer (FireBrowse)CDK17 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5128
GTEX Portal (Tissue expression)CDK17
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ00537   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ00537  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ00537
Splice isoforms : SwissVarQ00537
Catalytic activity : Enzyme2.7.11.22 [ Enzyme-Expasy ]   2.7.11.222.7.11.22 [ IntEnz-EBI ]   2.7.11.22 [ BRENDA ]   2.7.11.22 [ KEGG ]   
PhosPhoSitePlusQ00537
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)CDK17
DMDM Disease mutations5128
Blocks (Seattle)CDK17
SuperfamilyQ00537
Human Protein AtlasENSG00000059758
Peptide AtlasQ00537
HPRD09141
IPIIPI00376955   IPI01011116   IPI01021934   IPI01020734   IPI01020863   IPI01021011   IPI00954819   
Protein Interaction databases
DIP (DOE-UCLA)Q00537
IntAct (EBI)Q00537
FunCoupENSG00000059758
BioGRIDCDK17
STRING (EMBL)CDK17
ZODIACCDK17
Ontologies - Pathways
QuickGOQ00537
Ontology : AmiGOprotein kinase activity  protein serine/threonine kinase activity  cyclin-dependent protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  
Ontology : EGO-EBIprotein kinase activity  protein serine/threonine kinase activity  cyclin-dependent protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  
NDEx NetworkCDK17
Atlas of Cancer Signalling NetworkCDK17
Wikipedia pathwaysCDK17
Orthology - Evolution
OrthoDB5128
GeneTree (enSembl)ENSG00000059758
Phylogenetic Trees/Animal Genes : TreeFamCDK17
HOVERGENQ00537
HOGENOMQ00537
Homologs : HomoloGeneCDK17
Homology/Alignments : Family Browser (UCSC)CDK17
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDK17 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDK17
dbVarCDK17
ClinVarCDK17
1000_GenomesCDK17 
Exome Variant ServerCDK17
ExAC (Exome Aggregation Consortium)CDK17 (select the gene name)
Genetic variants : HAPMAP5128
Genomic Variants (DGV)CDK17 [DGVbeta]
DECIPHERCDK17 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDK17 
Mutations
ICGC Data PortalCDK17 
TCGA Data PortalCDK17 
Broad Tumor PortalCDK17
OASIS PortalCDK17 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDK17  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDK17
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDK17
DgiDB (Drug Gene Interaction Database)CDK17
DoCM (Curated mutations)CDK17 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDK17 (select a term)
intoGenCDK17
Cancer3DCDK17(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603440   
Orphanet
MedgenCDK17
Genetic Testing Registry CDK17
NextProtQ00537 [Medical]
TSGene5128
GENETestsCDK17
Target ValidationCDK17
Huge Navigator CDK17 [HugePedia]
snp3D : Map Gene to Disease5128
BioCentury BCIQCDK17
ClinGenCDK17
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5128
Chemical/Pharm GKB GenePA33096
Clinical trialCDK17
Miscellaneous
canSAR (ICR)CDK17 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDK17
EVEXCDK17
GoPubMedCDK17
iHOPCDK17
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:27:45 CEST 2017

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