CDK18 (cyclin dependent kinase 18)

2006-10-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
PCTAIRE,PCTAIRE3,PCTK3
FUSION GENES

Other Information

Locus ID:

NCBI: 5129
MIM: 169190
HGNC: 8751
Ensembl: ENSG00000117266

Variants:

dbSNP: 5129
ClinVar: 5129
TCGA: ENSG00000117266
COSMIC: CDK18

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117266ENST00000360066Q07002
ENSG00000117266ENST00000360066A0A024R996
ENSG00000117266ENST00000419301A0A0A0MSJ6
ENSG00000117266ENST00000429964Q07002
ENSG00000117266ENST00000429964A0A024R996
ENSG00000117266ENST00000443813D6R9B0
ENSG00000117266ENST00000462976D6R9X1
ENSG00000117266ENST00000478560D6RA44
ENSG00000117266ENST00000504648D6R9X1
ENSG00000117266ENST00000506215D6RGH0
ENSG00000117266ENST00000506784Q07002
ENSG00000117266ENST00000506784A0A024R980
ENSG00000117266ENST00000512922D6R9X1
ENSG00000117266ENST00000515494D6R9X1

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
273820662016Human CDK18 promotes replication stress signaling and genome stability.14
167661952006The regulation of tau phosphorylation by PCTAIRE 3: implications for the pathogenesis of Alzheimer's disease.11
268857532016Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology.6
312669512019Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma.4
150199842004Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain.0

Citation

Dessen P

CDK18 (cyclin dependent kinase 18)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43398/cdk18