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CDK5RAP2 (CDK5 regulatory subunit associated protein 2)

Identity

Other namesC48
Cep215
MCPH3
HGNC (Hugo) CDK5RAP2
LocusID (NCBI) 55755
Location 9q33.2
Location_base_pair Starts at 123151147 and ends at 123342437 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CDK5RAP2   18672
Entrez_Gene (NCBI)CDK5RAP2  55755  CDK5 regulatory subunit associated protein 2
Cards
GeneCards (Weizmann)CDK5RAP2
Ensembl (Hinxton)ENSG00000136861 [Gene_View]  chr9:123151147-123342437 [Contig_View]  CDK5RAP2 [Vega]
AceView (NCBI)CDK5RAP2
Genatlas (Paris)CDK5RAP2
SOURCE (Stanford)NM_001011649 NM_001272039 NM_018249
Genomic and cartography
GoldenPath (UCSC)CDK5RAP2  -  9q33.2   chr9:123151147-123342437 -  9q33.2   [Description]    (hg19-Feb_2009)
EnsemblCDK5RAP2 - 9q33.2 [CytoView]
Mapping of homologs : NCBICDK5RAP2 [Mapview]
OMIM604804   608201   
Gene and transcription
Genbank (Entrez)AB046853 AF087969 AF448860 AK001729 AK025867
RefSeq transcript (SRS)NM_001011649 NM_001272039 NM_018249
RefSeq transcript (Entrez)NM_001011649 NM_001272039 NM_018249
RefSeq genomic (SRS)AC_000141 NC_000009 NC_018920 NG_008999 NT_008470 NW_001839237 NW_004078058
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NG_008999 NT_008470 NW_001839237 NW_004078058
Consensus coding sequences : CCDS (NCBI)CDK5RAP2
Cluster EST : UnigeneHs.269560 [ SRS ] Hs.269560 [ NCBI ]
CGAP (NCI)Hs.269560
Alternative Splicing : Fast-db (Paris)GSHG0031108
Alternative Splicing GalleryENSG00000136861
Gene ExpressionCDK5RAP2 [ NCBI-GEO ]   CDK5RAP2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96SN8 (SRS) Q96SN8 (Uniprot)
NextProtQ96SN8
With graphics : InterProQ96SN8
Splice isoforms : SwissVarQ96SN8(Swissvar)
Domains : Interpro (SRS)Spindle_assoc   
Domains : Interpro (EBI)Spindle_assoc   
Related proteins : CluSTrQ96SN8
Domain families : Pfam (SRS)Microtub_assoc (PF07989)   
Domain families : Pfam (Sanger)Microtub_assoc (PF07989)   
Domain families : Pfam (NCBI)pfam07989   
DMDM55755
Blocks (Seattle)Q96SN8
Human Protein AtlasENSG00000136861
HPRD09740
IPIIPI00329038   IPI00329039   IPI00384417   IPI00384418   IPI00385005   IPI00746700   IPI00946374   IPI00946528   IPI00946764   
Protein Interaction databases
DIP (DOE-UCLA)Q96SN8
IntAct (EBI)Q96SN8
FunCoupENSG00000136861
REACTOMECDK5RAP2
Protein Interaction Database55755
BioGRIDCDK5RAP2
InParanoidQ96SN8
Interologous Interaction database Q96SN8
IntegromeDBCDK5RAP2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CDK5RAP2
SNP (GeneSNP Utah)CDK5RAP2
SNP : HGBaseCDK5RAP2
Genetic variants : HAPMAPCDK5RAP2
Somatic Mutations in Cancer : COSMICCDK5RAP2 
CONAN: Copy Number AnalysisCDK5RAP2 
Translocation Breakpoints in Cancer : TICdbCDK5RAP2 
Mutations and Diseases : HGMDCDK5RAP2
OMIM604804    608201   
GENETests604804    608201   
Disease Genetic AssociationCDK5RAP2
Huge Navigator CDK5RAP2 [HugePedia]  CDK5RAP2 [HugeCancerGEM]
Genomic VariantsCDK5RAP2  CDK5RAP2 [DGVbeta]
snp3D : Map Gene to Disease55755
General knowledge
Homologs : HomoloGeneCDK5RAP2
Homology/Alignments : Family Browser (UCSC)CDK5RAP2
Phylogenetic Trees/Animal Genes : TreeFamCDK5RAP2
Chemical/Protein Interactions : CTD55755
Chemical/Pharm GKB GenePA38632
Clinical trialCDK5RAP2
Cancer Resource (Charite)ENSG00000136861
Ontology : AmiGOG2/M transition of mitotic cell cycle  establishment of mitotic spindle orientation  microtubule cytoskeleton organization  pericentriolar material  mitotic cell cycle  spindle pole  microtubule bundle formation  protein binding  calmodulin binding  cytoplasm  Golgi apparatus  centrosome  cytosol  cytoskeleton  microtubule  chromosome segregation  brain development  brain development  microtubule binding  tubulin binding  protein kinase binding  neurogenesis  cell junction  transcription regulatory region DNA binding  regulation of neuron differentiation  negative regulation of neuron differentiation  positive regulation of transcription, DNA-dependent  negative regulation of centriole replication  perinuclear region of cytoplasm  centrosome organization  regulation of spindle checkpoint  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  establishment of mitotic spindle orientation  microtubule cytoskeleton organization  pericentriolar material  mitotic cell cycle  spindle pole  microtubule bundle formation  protein binding  calmodulin binding  cytoplasm  Golgi apparatus  centrosome  cytosol  cytoskeleton  microtubule  chromosome segregation  brain development  brain development  microtubule binding  tubulin binding  protein kinase binding  neurogenesis  cell junction  transcription regulatory region DNA binding  regulation of neuron differentiation  negative regulation of neuron differentiation  positive regulation of transcription, DNA-dependent  negative regulation of centriole replication  perinuclear region of cytoplasm  centrosome organization  regulation of spindle checkpoint  
Other databases
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
PubGeneCDK5RAP2
iHOPCDK5RAP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:44:55 CEST 2013
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