Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1024
MIM: 603184
HGNC: 1779
Ensembl: ENSG00000132964
Variants:
dbSNP: 1024
ClinVar: 1024
TCGA: ENSG00000132964
COSMIC: CDK8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000132964 | ENST00000381527 | P49336 |
| ENSG00000132964 | ENST00000465820 | A0A0D9SFZ2 |
| ENSG00000132964 | ENST00000536792 | F5H6D4 |
| ENSG00000132964 | ENST00000625988 | A0A0D9SEP3 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38193604 | 2024 | Expanding the phenotypic spectrum for CDK8-related disease: A case report. | 0 |
| 38409448 | 2024 | NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells. | 0 |
| 38193604 | 2024 | Expanding the phenotypic spectrum for CDK8-related disease: A case report. | 0 |
| 38409448 | 2024 | NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells. | 0 |
| 36737782 | 2023 | Loss of miR-26b-5p promotes gastric cancer progression via miR-26b-5p-PDE4B/CDK8-STAT3 feedback loop. | 6 |
| 37235474 | 2023 | Transcriptome-based chemical screens identify CDK8 as a common barrier in multiple cell reprogramming systems. | 3 |
| 37378433 | 2023 | CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins. | 7 |
| 36737782 | 2023 | Loss of miR-26b-5p promotes gastric cancer progression via miR-26b-5p-PDE4B/CDK8-STAT3 feedback loop. | 6 |
| 37235474 | 2023 | Transcriptome-based chemical screens identify CDK8 as a common barrier in multiple cell reprogramming systems. | 3 |
| 37378433 | 2023 | CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins. | 7 |
| 35181333 | 2022 | Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer. | 5 |
| 35605413 | 2022 | Cyclin-dependent kinase 8 is an independent prognosticator in uterine leiomyosarcoma. | 1 |
| 36006697 | 2022 | CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF. | 3 |
| 36233050 | 2022 | A Common Variant in the CDK8 Gene Is Associated with Sporadic Pituitary Adenomas in the Portuguese Population: A Case-Control Study. | 0 |
| 36292630 | 2022 | Identification of Cdk8 and Cdkn2d as New Prame-Target Genes in 2C-like Embryonic Stem Cells. | 1 |
Citation
Dessen P
CDK8 (cyclin dependent kinase 8)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40036/cdk8
