CDKL1 (cyclin dependent kinase like 1)

2006-10-01  

Identity

HGNC
LOCATION
14q21.3
LOCUSID
ALIAS
KKIALRE,P42
FUSION GENES

Other Information

Locus ID:

NCBI: 8814
MIM: 603441
HGNC: 1781
Ensembl: ENSG00000100490

Variants:

dbSNP: 8814
ClinVar: 8814
TCGA: ENSG00000100490
COSMIC: CDKL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100490ENST00000395834Q00532
ENSG00000100490ENST00000525911H0YCE5
ENSG00000100490ENST00000534267H0YE65

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
223696972012A role for Cdkl1 in the development of gastric cancer.8
228044582012Evaluation of cyclin-dependent kinase-like 1 expression in breast cancer tissues and its regulation in cancer cell growth.5
292627322018Chk1 modulates the interaction between myosin phosphatase targeting protein 1 (MYPT1) and protein phosphatase 1cβ (PP1cβ).3
308024952019CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin.0
308910732019Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.0

Citation

Dessen P

CDKL1 (cyclin dependent kinase like 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43203/cdkl1