CDKN2B-AS1 (CDKN2B antisense RNA 1)

2012-02-01  

Identity

LOCATION
9p21.3
LOCUSID
ALIAS
ANRIL,CDKN2B-AS,CDKN2BAS,NCRNA00089,PCAT12,p15AS
FUSION GENES

Other Information

Locus ID:

NCBI: 100048912
MIM: 613149
HGNC: 34341
Ensembl: ENSG00000240498

Variants:

dbSNP: 100048912
ClinVar: 100048912
TCGA: ENSG00000240498
COSMIC: CDKN2B-AS1

RNA/Proteins

Expression (GTEx)

0
1
2
3
4

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164712462Antiinflammatory agents, non-steroidsChemicalClinicalAnnotationassociatedPD20538124
PA165108401Acute coronary syndromeDiseaseClinicalAnnotationassociatedPD20538124

References

Pubmed IDYearTitleCitations
205419992010Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a.510
211511782011Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene.401
215325712011Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1.163
203867402010Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.145
203867402010Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.145
255047552015Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression.131
221784232012Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B.94
206019572010A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.78
206019572010A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.78
238139742013The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.71

Citation

Dessen P

CDKN2B-AS1 (CDKN2B antisense RNA 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-02-01

Online version: http://atlasgeneticsoncology.org/gene/52600/cdkn2b-as1