CDKN3 (cyclin dependent kinase inhibitor 3)

2003-05-01  

Identity

HGNC
LOCATION
14q22.2
LOCUSID
ALIAS
CDI1,CIP2,KAP,KAP1
FUSION GENES

Other Information

Locus ID:

NCBI: 1033
MIM: 123832
HGNC: 1791
Ensembl: ENSG00000100526

Variants:

dbSNP: 1033
ClinVar: 1033
TCGA: ENSG00000100526
COSMIC: CDKN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100526ENST00000335183Q16667
ENSG00000100526ENST00000395577F8WD24
ENSG00000100526ENST00000442975Q16667
ENSG00000100526ENST00000458126H7C0S3
ENSG00000100526ENST00000541304F5H232
ENSG00000100526ENST00000543789G3V1K6
ENSG00000100526ENST00000556102G3V2J7
ENSG00000100526ENST00000611205A0A087WWK3
ENSG00000100526ENST00000620759A0A087WW25

Expression (GTEx)

0
50
100
150
200

References

Pubmed IDYearTitleCitations
151475182004Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene.44
170560142006KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction.30
237751902013The tumor suppressor CDKN3 controls mitosis.29
197283352010High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer.26
234052412013Mitosis is a source of potential markers for screening and survival and therapeutic targets in cervical cancer.26
223909362012Cyclin-dependent kinase inhibitor 3 is overexpressed in hepatocellular carcinoma and promotes tumor cell proliferation.19
265546482015Overexpression of major CDKN3 transcripts is associated with poor survival in lung adenocarcinoma.18
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.16
215352702011Cyclin-dependent kinase inhibitor 3 (CDKN3) novel cell cycle computational network between human non-malignancy associated hepatitis/cirrhosis and hepatocellular carcinoma (HCC) transformation.15
235556232013Frequent engagement of RelB activation is critical for cell survival in multiple myeloma.15

Citation

Dessen P

CDKN3 (cyclin dependent kinase inhibitor 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40039/cdkn3