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CDS2 (CDP-diacylglycerol synthase 2)

Identity

Other alias-
HGNC (Hugo) CDS2
LocusID (NCBI) 8760
Atlas_Id 46940
Location 20p12.3  [Link to chromosome band 20p12]
Location_base_pair Starts at 5126761 and ends at 5197887 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CDS2 (20p12.3) / ANKRD11 (16q24.3)CDS2 (20p12.3) / CRK (17p13.3)FKBP1A (20p13) / CDS2 (20p12.3)
PIK3CD (1p36.22) / CDS2 (20p12.3)RNF24 (20p13) / CDS2 (20p12.3)SLX4IP (20p12.2) / CDS2 (20p12.3)
UBXN11 (1p36.11) / CDS2 (20p12.3)C20orf94 CDS2 20p12.3FKBP1A 20p13 / CDS2 20p12.3
RNF24 20p13 / CDS2 20p12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDS2   1801
Cards
Entrez_Gene (NCBI)CDS2  8760  CDP-diacylglycerol synthase 2
Aliases
GeneCards (Weizmann)CDS2
Ensembl hg19 (Hinxton)ENSG00000101290 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101290 [Gene_View]  chr20:5126761-5197887 [Contig_View]  CDS2 [Vega]
ICGC DataPortalENSG00000101290
TCGA cBioPortalCDS2
AceView (NCBI)CDS2
Genatlas (Paris)CDS2
WikiGenes8760
SOURCE (Princeton)CDS2
Genetics Home Reference (NIH)CDS2
Genomic and cartography
GoldenPath hg38 (UCSC)CDS2  -     chr20:5126761-5197887 +  20p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDS2  -     20p12.3   [Description]    (hg19-Feb_2009)
EnsemblCDS2 - 20p12.3 [CytoView hg19]  CDS2 - 20p12.3 [CytoView hg38]
Mapping of homologs : NCBICDS2 [Mapview hg19]  CDS2 [Mapview hg38]
OMIM603549   
Gene and transcription
Genbank (Entrez)AF069532 AK001414 AK022998 AK027695 AK091045
RefSeq transcript (Entrez)NM_003818
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDS2
Cluster EST : UnigeneHs.126857 [ NCBI ]
CGAP (NCI)Hs.126857
Alternative Splicing GalleryENSG00000101290
Gene ExpressionCDS2 [ NCBI-GEO ]   CDS2 [ EBI - ARRAY_EXPRESS ]   CDS2 [ SEEK ]   CDS2 [ MEM ]
Gene Expression Viewer (FireBrowse)CDS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8760
GTEX Portal (Tissue expression)CDS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95674   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95674  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95674
Splice isoforms : SwissVarO95674
Catalytic activity : Enzyme2.7.7.41 [ Enzyme-Expasy ]   2.7.7.412.7.7.41 [ IntEnz-EBI ]   2.7.7.41 [ BRENDA ]   2.7.7.41 [ KEGG ]   
PhosPhoSitePlusO95674
Domaine pattern : Prosite (Expaxy)CDS (PS01315)   
Domains : Interpro (EBI)PC_trans    PC_Trfase_euk   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CDS2
DMDM Disease mutations8760
Blocks (Seattle)CDS2
SuperfamilyO95674
Human Protein AtlasENSG00000101290
Peptide AtlasO95674
HPRD09150
IPIIPI00032150   IPI00646081   IPI00908510   IPI01014670   
Protein Interaction databases
DIP (DOE-UCLA)O95674
IntAct (EBI)O95674
FunCoupENSG00000101290
BioGRIDCDS2
STRING (EMBL)CDS2
ZODIACCDS2
Ontologies - Pathways
QuickGOO95674
Ontology : AmiGOphosphatidate cytidylyltransferase activity  phosphatidate cytidylyltransferase activity  phosphatidate cytidylyltransferase activity  mitochondrial inner membrane  endoplasmic reticulum membrane  phosphatidylglycerol biosynthetic process  phosphatidylglycerol biosynthetic process  membrane  integral component of membrane  CDP-diacylglycerol biosynthetic process  CDP-diacylglycerol biosynthetic process  
Ontology : EGO-EBIphosphatidate cytidylyltransferase activity  phosphatidate cytidylyltransferase activity  phosphatidate cytidylyltransferase activity  mitochondrial inner membrane  endoplasmic reticulum membrane  phosphatidylglycerol biosynthetic process  phosphatidylglycerol biosynthetic process  membrane  integral component of membrane  CDP-diacylglycerol biosynthetic process  CDP-diacylglycerol biosynthetic process  
Pathways : KEGGGlycerophospholipid metabolism    Phosphatidylinositol signaling system   
NDEx NetworkCDS2
Atlas of Cancer Signalling NetworkCDS2
Wikipedia pathwaysCDS2
Orthology - Evolution
OrthoDB8760
GeneTree (enSembl)ENSG00000101290
Phylogenetic Trees/Animal Genes : TreeFamCDS2
HOVERGENO95674
HOGENOMO95674
Homologs : HomoloGeneCDS2
Homology/Alignments : Family Browser (UCSC)CDS2
Gene fusions - Rearrangements
Fusion : MitelmanFKBP1A/CDS2 [20p13/20p12.3]  [t(20;20)(p12;p13)]  
Fusion : MitelmanRNF24/CDS2 [20p13/20p12.3]  [t(20;20)(p12;p13)]  
Fusion : MitelmanSLX4IP/CDS2 [20p12.2/20p12.3]  [t(20;20)(p12;p12)]  
Fusion: TCGAC20orf94 CDS2 20p12.3 HNSC
Fusion: TCGAFKBP1A 20p13 CDS2 20p12.3 HNSC
Fusion: TCGARNF24 20p13 CDS2 20p12.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDS2
dbVarCDS2
ClinVarCDS2
1000_GenomesCDS2 
Exome Variant ServerCDS2
ExAC (Exome Aggregation Consortium)CDS2 (select the gene name)
Genetic variants : HAPMAP8760
Genomic Variants (DGV)CDS2 [DGVbeta]
DECIPHERCDS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDS2 
Mutations
ICGC Data PortalCDS2 
TCGA Data PortalCDS2 
Broad Tumor PortalCDS2
OASIS PortalCDS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDS2
DgiDB (Drug Gene Interaction Database)CDS2
DoCM (Curated mutations)CDS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDS2 (select a term)
intoGenCDS2
Cancer3DCDS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603549   
Orphanet
MedgenCDS2
Genetic Testing Registry CDS2
NextProtO95674 [Medical]
TSGene8760
GENETestsCDS2
Target ValidationCDS2
Huge Navigator CDS2 [HugePedia]
snp3D : Map Gene to Disease8760
BioCentury BCIQCDS2
ClinGenCDS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8760
Chemical/Pharm GKB GenePA26347
Clinical trialCDS2
Miscellaneous
canSAR (ICR)CDS2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDS2
EVEXCDS2
GoPubMedCDS2
iHOPCDS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:57:32 CEST 2017

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