CDX4 (caudal type homeobox 4)

2014-11-01 Affiliation

Identity

HGNC

CDX4

LOCATION

Xq13.2

LOCUSID

1046

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 1046
MIM: 300025
HGNC: 1808
Ensembl: ENSG00000131264

Variants:

dbSNP: 1046
ClinVar: 1046
TCGA: ENSG00000131264
COSMIC: CDX4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000131264	ENST00000373514	O14627

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
21471217	2011	HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells.	14
23038246	2012	β-Catenin activates the HOXA10 and CDX4 genes in myeloid progenitor cells.	9
28408465	2017	Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4.	4
21518475	2011	[Expression and clinical significance of caudal type homeobox transcription factor-2 in adult acute lymphocytic leukemia].	1
22721648	2012	Ectopic expression of CDX4 in human mesenchymal stem cells does not affect HOX gene expression or induce hematopoietic reprogramming.	0

Citation

Dessen P

CDX4 (caudal type homeobox 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61670/cdx4