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CELA1 (chymotrypsin like elastase family member 1)

Identity

Alias_namesELA1
elastase 1, pancreatic
chymotrypsin-like elastase family, member 1
Other alias
HGNC (Hugo) CELA1
LocusID (NCBI) 1990
Atlas_Id 55958
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 51722227 and ends at 51740463 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CELA1   3308
Cards
Entrez_Gene (NCBI)CELA1  1990  chymotrypsin like elastase family member 1
AliasesELA1
GeneCards (Weizmann)CELA1
Ensembl hg19 (Hinxton)ENSG00000139610 [Gene_View]  chr12:51722227-51740463 [Contig_View]  CELA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000139610 [Gene_View]  chr12:51722227-51740463 [Contig_View]  CELA1 [Vega]
ICGC DataPortalENSG00000139610
TCGA cBioPortalCELA1
AceView (NCBI)CELA1
Genatlas (Paris)CELA1
WikiGenes1990
SOURCE (Princeton)CELA1
Genetics Home Reference (NIH)CELA1
Genomic and cartography
GoldenPath hg19 (UCSC)CELA1  -     chr12:51722227-51740463 -  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CELA1  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblCELA1 - 12q13.13 [CytoView hg19]  CELA1 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBICELA1 [Mapview hg19]  CELA1 [Mapview hg38]
OMIM130120   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001971
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CELA1
Cluster EST : UnigeneHs.348395 [ NCBI ]
CGAP (NCI)Hs.348395
Alternative Splicing GalleryENSG00000139610
Gene ExpressionCELA1 [ NCBI-GEO ]   CELA1 [ EBI - ARRAY_EXPRESS ]   CELA1 [ SEEK ]   CELA1 [ MEM ]
Gene Expression Viewer (FireBrowse)CELA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1990
GTEX Portal (Tissue expression)CELA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UNI1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UNI1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UNI1
Splice isoforms : SwissVarQ9UNI1
Catalytic activity : Enzyme3.4.21.36 [ Enzyme-Expasy ]   3.4.21.363.4.21.36 [ IntEnz-EBI ]   3.4.21.36 [ BRENDA ]   3.4.21.36 [ KEGG ]   
PhosPhoSitePlusQ9UNI1
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)CELA1
DMDM Disease mutations1990
Blocks (Seattle)CELA1
SuperfamilyQ9UNI1
Human Protein AtlasENSG00000139610
Peptide AtlasQ9UNI1
HPRD00553
IPIIPI00019729   
Protein Interaction databases
DIP (DOE-UCLA)Q9UNI1
IntAct (EBI)Q9UNI1
FunCoupENSG00000139610
BioGRIDCELA1
STRING (EMBL)CELA1
ZODIACCELA1
Ontologies - Pathways
QuickGOQ9UNI1
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  serine-type endopeptidase activity  extracellular space  proteolysis  inflammatory response  post-embryonic development  Wnt signaling pathway  exocrine pancreas development  multicellular organism growth  regulation of cell proliferation  regulation of cell differentiation  positive regulation of angiogenesis  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  tissue remodeling  elastin catabolic process  pancreas morphogenesis  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  serine-type endopeptidase activity  extracellular space  proteolysis  inflammatory response  post-embryonic development  Wnt signaling pathway  exocrine pancreas development  multicellular organism growth  regulation of cell proliferation  regulation of cell differentiation  positive regulation of angiogenesis  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  tissue remodeling  elastin catabolic process  pancreas morphogenesis  
Pathways : BIOCARTAProepithelin Conversion to Epithelin and Wound Repair Control [Genes]   
NDEx NetworkCELA1
Atlas of Cancer Signalling NetworkCELA1
Wikipedia pathwaysCELA1
Orthology - Evolution
OrthoDB1990
GeneTree (enSembl)ENSG00000139610
Phylogenetic Trees/Animal Genes : TreeFamCELA1
HOVERGENQ9UNI1
HOGENOMQ9UNI1
Homologs : HomoloGeneCELA1
Homology/Alignments : Family Browser (UCSC)CELA1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCELA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CELA1
dbVarCELA1
ClinVarCELA1
1000_GenomesCELA1 
Exome Variant ServerCELA1
ExAC (Exome Aggregation Consortium)CELA1 (select the gene name)
Genetic variants : HAPMAP1990
Genomic Variants (DGV)CELA1 [DGVbeta]
DECIPHER (Syndromes)12:51722227-51740463  ENSG00000139610
CONAN: Copy Number AnalysisCELA1 
Mutations
ICGC Data PortalCELA1 
TCGA Data PortalCELA1 
Broad Tumor PortalCELA1
OASIS PortalCELA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCELA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCELA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CELA1
DgiDB (Drug Gene Interaction Database)CELA1
DoCM (Curated mutations)CELA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CELA1 (select a term)
intoGenCELA1
Cancer3DCELA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM130120   
Orphanet
MedgenCELA1
Genetic Testing Registry CELA1
NextProtQ9UNI1 [Medical]
TSGene1990
GENETestsCELA1
Huge Navigator CELA1 [HugePedia]
snp3D : Map Gene to Disease1990
BioCentury BCIQCELA1
ClinGenCELA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1990
Chemical/Pharm GKB GenePA27734
Clinical trialCELA1
Miscellaneous
canSAR (ICR)CELA1 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCELA1
EVEXCELA1
GoPubMedCELA1
iHOPCELA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:59:56 CET 2017

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