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CELA2A (chymotrypsin-like elastase family, member 2A)

Identity

Alias_nameschymotrypsin-like elastase family, member 2A
Alias_symbol (synonym)ELA2A
Other aliasPE-1
HGNC (Hugo) CELA2A
LocusID (NCBI) 63036
Atlas_Id 61691
Location 1p36.21  [Link to chromosome band 1p36]
Location_base_pair Starts at 15783223 and ends at 15798586 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PER3 (1p36.23) / CELA2A (1p36.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CELA2A   24609
Cards
Entrez_Gene (NCBI)CELA2A  63036  chymotrypsin-like elastase family, member 2A
AliasesELA2A; PE-1
GeneCards (Weizmann)CELA2A
Ensembl hg19 (Hinxton)ENSG00000142615 [Gene_View]  chr1:15783223-15798586 [Contig_View]  CELA2A [Vega]
Ensembl hg38 (Hinxton)ENSG00000142615 [Gene_View]  chr1:15783223-15798586 [Contig_View]  CELA2A [Vega]
ICGC DataPortalENSG00000142615
TCGA cBioPortalCELA2A
AceView (NCBI)CELA2A
Genatlas (Paris)CELA2A
WikiGenes63036
SOURCE (Princeton)CELA2A
Genetics Home Reference (NIH)CELA2A
Genomic and cartography
GoldenPath hg19 (UCSC)CELA2A  -     chr1:15783223-15798586 +  1p36.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CELA2A  -     1p36.21   [Description]    (hg38-Dec_2013)
EnsemblCELA2A - 1p36.21 [CytoView hg19]  CELA2A - 1p36.21 [CytoView hg38]
Mapping of homologs : NCBICELA2A [Mapview hg19]  CELA2A [Mapview hg38]
OMIM609443   
Gene and transcription
Genbank (Entrez)AK056678 AK312198 BC007031 BC069331 BC069432
RefSeq transcript (Entrez)NM_033440
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)CELA2A
Cluster EST : UnigeneHs.631866 [ NCBI ]
CGAP (NCI)Hs.631866
Alternative Splicing GalleryENSG00000142615
Gene ExpressionCELA2A [ NCBI-GEO ]   CELA2A [ EBI - ARRAY_EXPRESS ]   CELA2A [ SEEK ]   CELA2A [ MEM ]
Gene Expression Viewer (FireBrowse)CELA2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63036
GTEX Portal (Tissue expression)CELA2A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08217   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08217  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08217
Splice isoforms : SwissVarP08217
Catalytic activity : Enzyme3.4.21.71 [ Enzyme-Expasy ]   3.4.21.713.4.21.71 [ IntEnz-EBI ]   3.4.21.71 [ BRENDA ]   3.4.21.71 [ KEGG ]   
PhosPhoSitePlusP08217
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1    Peptidase_S1_AS    Peptidase_S1A    Trypsin-like_Pept_dom   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)CELA2A
DMDM Disease mutations63036
Blocks (Seattle)CELA2A
SuperfamilyP08217
Human Protein AtlasENSG00000142615
Peptide AtlasP08217
HPRD06495
IPIIPI00027722   IPI00829925   
Protein Interaction databases
DIP (DOE-UCLA)P08217
IntAct (EBI)P08217
FunCoupENSG00000142615
BioGRIDCELA2A
STRING (EMBL)CELA2A
ZODIACCELA2A
Ontologies - Pathways
QuickGOP08217
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  proteolysis  serine hydrolase activity  keratohyalin granule  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  proteolysis  serine hydrolase activity  keratohyalin granule  
Pathways : BIOCARTAProepithelin Conversion to Epithelin and Wound Repair Control [Genes]   
Pathways : KEGGPancreatic secretion    Protein digestion and absorption   
NDEx NetworkCELA2A
Atlas of Cancer Signalling NetworkCELA2A
Wikipedia pathwaysCELA2A
Orthology - Evolution
OrthoDB63036
GeneTree (enSembl)ENSG00000142615
Phylogenetic Trees/Animal Genes : TreeFamCELA2A
HOVERGENP08217
HOGENOMP08217
Homologs : HomoloGeneCELA2A
Homology/Alignments : Family Browser (UCSC)CELA2A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCELA2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CELA2A
dbVarCELA2A
ClinVarCELA2A
1000_GenomesCELA2A 
Exome Variant ServerCELA2A
ExAC (Exome Aggregation Consortium)CELA2A (select the gene name)
Genetic variants : HAPMAP63036
Genomic Variants (DGV)CELA2A [DGVbeta]
DECIPHER (Syndromes)1:15783223-15798586  ENSG00000142615
CONAN: Copy Number AnalysisCELA2A 
Mutations
ICGC Data PortalCELA2A 
TCGA Data PortalCELA2A 
Broad Tumor PortalCELA2A
OASIS PortalCELA2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCELA2A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCELA2A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CELA2A
DgiDB (Drug Gene Interaction Database)CELA2A
DoCM (Curated mutations)CELA2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CELA2A (select a term)
intoGenCELA2A
Cancer3DCELA2A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609443   
Orphanet
MedgenCELA2A
Genetic Testing Registry CELA2A
NextProtP08217 [Medical]
TSGene63036
GENETestsCELA2A
Huge Navigator CELA2A [HugePedia]
snp3D : Map Gene to Disease63036
BioCentury BCIQCELA2A
ClinGenCELA2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63036
Chemical/Pharm GKB GenePA165750794
Clinical trialCELA2A
Miscellaneous
canSAR (ICR)CELA2A (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCELA2A
EVEXCELA2A
GoPubMedCELA2A
iHOPCELA2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:59:02 CET 2017

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