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CELF4 (CUGBP Elav-like family member 4)

Identity

Alias_namesBRUNOL4
Bruno (Drosophila) -like 4, RNA binding protein
bruno-like 4, RNA binding protein (Drosophila)
Other aliasCELF-4
HGNC (Hugo) CELF4
LocusID (NCBI) 56853
Atlas_Id 61696
Location 18q12.2  [Link to chromosome band 18q12]
Location_base_pair Starts at 37243045 and ends at 37566037 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CELF4 (18q12.2) / FRS2 (12q15)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CELF4   14015
Cards
Entrez_Gene (NCBI)CELF4  56853  CUGBP Elav-like family member 4
AliasesBRUNOL4; CELF-4
GeneCards (Weizmann)CELF4
Ensembl hg19 (Hinxton)ENSG00000101489 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101489 [Gene_View]  chr18:37243045-37566037 [Contig_View]  CELF4 [Vega]
ICGC DataPortalENSG00000101489
TCGA cBioPortalCELF4
AceView (NCBI)CELF4
Genatlas (Paris)CELF4
WikiGenes56853
SOURCE (Princeton)CELF4
Genetics Home Reference (NIH)CELF4
Genomic and cartography
GoldenPath hg38 (UCSC)CELF4  -     chr18:37243045-37566037 -  18q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CELF4  -     18q12.2   [Description]    (hg19-Feb_2009)
EnsemblCELF4 - 18q12.2 [CytoView hg19]  CELF4 - 18q12.2 [CytoView hg38]
Mapping of homologs : NCBICELF4 [Mapview hg19]  CELF4 [Mapview hg38]
OMIM612679   
Gene and transcription
Genbank (Entrez)AA669357 AB209774 AF141345 AF248650 AF248651
RefSeq transcript (Entrez)NM_001025087 NM_001025088 NM_001025089 NM_001330603 NM_020180
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CELF4
Cluster EST : UnigeneHs.600908 [ NCBI ]
CGAP (NCI)Hs.600908
Alternative Splicing GalleryENSG00000101489
Gene ExpressionCELF4 [ NCBI-GEO ]   CELF4 [ EBI - ARRAY_EXPRESS ]   CELF4 [ SEEK ]   CELF4 [ MEM ]
Gene Expression Viewer (FireBrowse)CELF4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56853
GTEX Portal (Tissue expression)CELF4
Human Protein AtlasENSG00000101489-CELF4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZC1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZC1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZC1
Splice isoforms : SwissVarQ9BZC1
PhosPhoSitePlusQ9BZC1
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)CELF4
DMDM Disease mutations56853
Blocks (Seattle)CELF4
PDB (SRS)2DGP    2DNK   
PDB (PDBSum)2DGP    2DNK   
PDB (IMB)2DGP    2DNK   
PDB (RSDB)2DGP    2DNK   
Structural Biology KnowledgeBase2DGP    2DNK   
SCOP (Structural Classification of Proteins)2DGP    2DNK   
CATH (Classification of proteins structures)2DGP    2DNK   
SuperfamilyQ9BZC1
Human Protein Atlas [tissue]ENSG00000101489-CELF4 [tissue]
Peptide AtlasQ9BZC1
HPRD12534
IPIIPI00853444   IPI00024603   IPI00853277   IPI00853216   IPI00384535   IPI00386504   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZC1
IntAct (EBI)Q9BZC1
FunCoupENSG00000101489
BioGRIDCELF4
STRING (EMBL)CELF4
ZODIACCELF4
Ontologies - Pathways
QuickGOQ9BZC1
Ontology : AmiGOalternative mRNA splicing, via spliceosome  regulation of alternative mRNA splicing, via spliceosome  translation repressor activity, nucleic acid binding  mRNA binding  nucleus  cytoplasm  mRNA splice site selection  germ cell development  embryo development  negative regulation of translation  BRE binding  negative regulation of mRNA splicing, via spliceosome  positive regulation of mRNA splicing, via spliceosome  negative regulation of excitatory postsynaptic potential  regulation of retina development in camera-type eye  
Ontology : EGO-EBIalternative mRNA splicing, via spliceosome  regulation of alternative mRNA splicing, via spliceosome  translation repressor activity, nucleic acid binding  mRNA binding  nucleus  cytoplasm  mRNA splice site selection  germ cell development  embryo development  negative regulation of translation  BRE binding  negative regulation of mRNA splicing, via spliceosome  positive regulation of mRNA splicing, via spliceosome  negative regulation of excitatory postsynaptic potential  regulation of retina development in camera-type eye  
NDEx NetworkCELF4
Atlas of Cancer Signalling NetworkCELF4
Wikipedia pathwaysCELF4
Orthology - Evolution
OrthoDB56853
GeneTree (enSembl)ENSG00000101489
Phylogenetic Trees/Animal Genes : TreeFamCELF4
HOVERGENQ9BZC1
HOGENOMQ9BZC1
Homologs : HomoloGeneCELF4
Homology/Alignments : Family Browser (UCSC)CELF4
Gene fusions - Rearrangements
Fusion: Tumor Portal CELF4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCELF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CELF4
dbVarCELF4
ClinVarCELF4
1000_GenomesCELF4 
Exome Variant ServerCELF4
ExAC (Exome Aggregation Consortium)ENSG00000101489
GNOMAD BrowserENSG00000101489
Genetic variants : HAPMAP56853
Genomic Variants (DGV)CELF4 [DGVbeta]
DECIPHERCELF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCELF4 
Mutations
ICGC Data PortalCELF4 
TCGA Data PortalCELF4 
Broad Tumor PortalCELF4
OASIS PortalCELF4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCELF4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCELF4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CELF4
DgiDB (Drug Gene Interaction Database)CELF4
DoCM (Curated mutations)CELF4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CELF4 (select a term)
intoGenCELF4
Cancer3DCELF4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612679   
Orphanet
MedgenCELF4
Genetic Testing Registry CELF4
NextProtQ9BZC1 [Medical]
TSGene56853
GENETestsCELF4
Target ValidationCELF4
Huge Navigator CELF4 [HugePedia]
snp3D : Map Gene to Disease56853
BioCentury BCIQCELF4
ClinGenCELF4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56853
Chemical/Pharm GKB GenePA25428
Clinical trialCELF4
Miscellaneous
canSAR (ICR)CELF4 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCELF4
EVEXCELF4
GoPubMedCELF4
iHOPCELF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:42:14 CET 2017

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