| Nomenclature |
|---|
| HGNC (Hugo) | CENPA 1851 |
| Cards |
|---|
| Entrez_Gene (NCBI) | CENPA centromere protein A |
| Aliases | CENP-A; CenH3 |
| GeneCards (Weizmann) | CENPA |
| Ensembl hg19 (Hinxton) | ENSG00000115163 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000115163 [Gene_View] ENSG00000115163 [Sequence] chr2:26786056-26794587 [Contig_View] CENPA [Vega] |
| ICGC DataPortal | ENSG00000115163 |
| TCGA cBioPortal | CENPA |
| AceView (NCBI) | CENPA |
| Genatlas (Paris) | CENPA |
| SOURCE (Princeton) | CENPA |
| Genetics Home Reference (NIH) | CENPA |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | CENPA - chr2:26786056-26794587 + 2p23.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | CENPA - 2p23.3 [Description] (hg19-Feb_2009) |
| GoldenPath | CENPA - 2p23.3 [CytoView hg19] CENPA - 2p23.3 [CytoView hg38] |
| ImmunoBase | ENSG00000115163 |
| Genome Data Viewer NCBI | CENPA [Mapview hg19] |
| OMIM | 117139 |
| Gene and transcription |
|---|
| Genbank (Entrez) | BC000881 BC002703 BC011013 BT007246 U14518 |
| RefSeq transcript (Entrez) | NM_001042426 NM_001809 |
| Consensus coding sequences : CCDS (NCBI) | CENPA |
| Gene Expression | CENPA [ NCBI-GEO ] CENPA [ EBI - ARRAY_EXPRESS ]
CENPA [ SEEK ] CENPA [ MEM ] |
| Gene Expression Viewer (FireBrowse) | CENPA [ Firebrowse - Broad ] |
| Genevisible | Expression of CENPA in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 1058 |
| GTEX Portal (Tissue expression) | CENPA |
| Human Protein Atlas | ENSG00000115163-CENPA [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P49450 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P49450 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P49450 |
| PhosPhoSitePlus | P49450 |
| Domaine pattern : Prosite (Expaxy) | HISTONE_H3_2 (PS00959) |
| Domains : Interpro (EBI) | Histone-fold Histone_H2A/H2B/H3 Histone_H3/CENP-A |
| Domain families : Pfam (Sanger) | Histone (PF00125) |
| Domain families : Pfam (NCBI) | pfam00125 |
| Domain families : Smart (EMBL) | H3 (SM00428) |
| Conserved Domain (NCBI) | CENPA |
| PDB (RSDB) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6KDQ 6KDS 6L49 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG 6TEM |
| PDB Europe | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6KDQ 6KDS 6L49 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG 6TEM |
| PDB (PDBSum) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6KDQ 6KDS 6L49 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG 6TEM |
| PDB (IMB) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6KDQ 6KDS 6L49 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG 6TEM |
| Structural Biology KnowledgeBase | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6KDQ 6KDS 6L49 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG 6TEM |
| SCOP (Structural Classification of Proteins) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6KDQ 6KDS 6L49 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG 6TEM |
| CATH (Classification of proteins structures) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6KDQ 6KDS 6L49 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG 6TEM |
| Superfamily | P49450 |
| AlphaFold pdb e-kb | P49450 |
| Human Protein Atlas [tissue] | ENSG00000115163-CENPA [tissue] |
| HPRD | 00313 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P49450 |
| IntAct (EBI) | P49450 |
| BioGRID | CENPA |
| STRING (EMBL) | CENPA |
| ZODIAC | CENPA |
| Ontologies - Pathways |
|---|
| QuickGO | P49450 |
| Ontology : AmiGO | establishment of mitotic spindle orientation mitotic cytokinesis chromosome, centromeric region kinetochore condensed chromosome, centromeric region nucleosome inner kinetochore DNA binding chromatin binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm pericentric heterochromatin cytosol CENP-A containing nucleosome protein heterodimerization activity kinetochore assembly protein localization to chromosome, centromeric region |
| Ontology : EGO-EBI | establishment of mitotic spindle orientation mitotic cytokinesis chromosome, centromeric region kinetochore condensed chromosome, centromeric region nucleosome inner kinetochore DNA binding chromatin binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm pericentric heterochromatin cytosol CENP-A containing nucleosome protein heterodimerization activity kinetochore assembly protein localization to chromosome, centromeric region |
| NDEx Network | CENPA |
| Atlas of Cancer Signalling Network | CENPA |
| Wikipedia pathways | CENPA |
| Orthology - Evolution |
|---|
| OrthoDB | 1058 |
| GeneTree (enSembl) | ENSG00000115163 |
| Phylogenetic Trees/Animal Genes : TreeFam | CENPA |
| Homologs : HomoloGene | CENPA |
| Homology/Alignments : Family Browser (UCSC) | CENPA |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | CENPA |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | CENPA [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | CENPA |
| dbVar | CENPA |
| ClinVar | CENPA |
| Monarch | CENPA |
| 1000_Genomes | CENPA |
| Exome Variant Server | CENPA |
| GNOMAD Browser | ENSG00000115163 |
| Varsome Browser | CENPA |
| ACMG | CENPA variants |
| Varity | P49450 |
| Genomic Variants (DGV) | CENPA [DGVbeta] |
| DECIPHER | CENPA [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | CENPA |
| Mutations |
|---|
| ICGC Data Portal | CENPA |
| TCGA Data Portal | CENPA |
| Broad Tumor Portal | CENPA |
| OASIS Portal | CENPA [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | CENPA [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | CENPA |
| Mutations and Diseases : HGMD | CENPA |
| LOVD (Leiden Open Variation Database) | [gene] [transcripts] [variants] |
| BioMuta | CENPA |
| DgiDB (Drug Gene Interaction Database) | CENPA |
| DoCM (Curated mutations) | CENPA |
| CIViC (Clinical Interpretations of Variants in Cancer) | CENPA |
| Cancer3D | CENPA |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 117139 |
| Orphanet | |
| DisGeNET | CENPA |
| Medgen | CENPA |
| Genetic Testing Registry | CENPA
|
| NextProt | P49450 [Medical] |
| GENETests | CENPA |
| Target Validation | CENPA |
| Huge Navigator |
CENPA [HugePedia] |
| ClinGen | CENPA |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | CENPA |
| Protein Interactions : CTD | CENPA |
| Pharm GKB Gene | PA26396 |
| Pharos | P49450 |
| Clinical trial | CENPA |
| Miscellaneous |
|---|
| canSAR (ICR) | CENPA |
| Harmonizome | CENPA |
| ARCHS4 | CENPA |
| DataMed Index | CENPA |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 166 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | CENPA |
