| Nomenclature |
|---|
| HGNC (Hugo) | CENPA 1851 |
| Cards |
|---|
| Entrez_Gene (NCBI) | CENPA 1058 centromere protein A |
| Aliases | CENP-A; CenH3 |
| GeneCards (Weizmann) | CENPA |
| Ensembl hg19 (Hinxton) | ENSG00000115163 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000115163 [Gene_View] ENSG00000115163 [Sequence] chr2:26786014-26794587 [Contig_View] CENPA [Vega] |
| ICGC DataPortal | ENSG00000115163 |
| TCGA cBioPortal | CENPA |
| AceView (NCBI) | CENPA |
| Genatlas (Paris) | CENPA |
| WikiGenes | 1058 |
| SOURCE (Princeton) | CENPA |
| Genetics Home Reference (NIH) | CENPA |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | CENPA - chr2:26786014-26794587 + 2p23.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | CENPA - 2p23.3 [Description] (hg19-Feb_2009) |
| GoldenPath | CENPA - 2p23.3 [CytoView hg19] CENPA - 2p23.3 [CytoView hg38] |
| ImmunoBase | ENSG00000115163 |
| Mapping of homologs : NCBI | CENPA [Mapview hg19] CENPA [Mapview hg38] |
| OMIM | 117139 |
| Gene and transcription |
|---|
| Genbank (Entrez) | BC000881 BC002703 BC011013 BT007246 U14518 |
| RefSeq transcript (Entrez) | NM_001042426 NM_001809 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | CENPA |
| Cluster EST : Unigene | Hs.1594 [ NCBI ] |
| CGAP (NCI) | Hs.1594 |
| Alternative Splicing Gallery | ENSG00000115163 |
| Gene Expression | CENPA [ NCBI-GEO ] CENPA [ EBI - ARRAY_EXPRESS ]
CENPA [ SEEK ] CENPA [ MEM ] |
| Gene Expression Viewer (FireBrowse) | CENPA [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 1058 |
| GTEX Portal (Tissue expression) | CENPA |
| Human Protein Atlas | ENSG00000115163-CENPA [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P49450 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P49450 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P49450 |
| Splice isoforms : SwissVar | P49450 |
| PhosPhoSitePlus | P49450 |
| Domaine pattern : Prosite (Expaxy) | HISTONE_H3_2 (PS00959) |
| Domains : Interpro (EBI) | Histone-fold Histone_H2A/H2B/H3 Histone_H3/CENP-A |
| Domain families : Pfam (Sanger) | Histone (PF00125) |
| Domain families : Pfam (NCBI) | pfam00125 |
| Domain families : Smart (EMBL) | H3 (SM00428) |
| Conserved Domain (NCBI) | CENPA |
| DMDM Disease mutations | 1058 |
| Blocks (Seattle) | CENPA |
| PDB (RSDB) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 6BUZ 6C0W |
| PDB Europe | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 6BUZ 6C0W |
| PDB (PDBSum) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 6BUZ 6C0W |
| PDB (IMB) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 6BUZ 6C0W |
| Structural Biology KnowledgeBase | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 6BUZ 6C0W |
| SCOP (Structural Classification of Proteins) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 6BUZ 6C0W |
| CATH (Classification of proteins structures) | 3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 6BUZ 6C0W |
| Superfamily | P49450 |
| Human Protein Atlas [tissue] | ENSG00000115163-CENPA [tissue] |
| Peptide Atlas | P49450 |
| HPRD | 00313 |
| IPI | IPI00027152 IPI00333218 IPI00893283 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P49450 |
| IntAct (EBI) | P49450 |
| FunCoup | ENSG00000115163 |
| BioGRID | CENPA |
| STRING (EMBL) | CENPA |
| ZODIAC | CENPA |
| Ontologies - Pathways |
|---|
| QuickGO | P49450 |
| Ontology : AmiGO | establishment of mitotic spindle orientation mitotic cytokinesis chromosome, centromeric region condensed nuclear chromosome kinetochore condensed nuclear chromosome, centromeric region nucleosome nuclear nucleosome condensed chromosome inner kinetochore chromatin binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytosol viral process nucleosomal DNA binding nuclear pericentric heterochromatin CENP-A containing nucleosome assembly protein heterodimerization activity kinetochore assembly protein localization to chromosome, centromeric region |
| Ontology : EGO-EBI | establishment of mitotic spindle orientation mitotic cytokinesis chromosome, centromeric region condensed nuclear chromosome kinetochore condensed nuclear chromosome, centromeric region nucleosome nuclear nucleosome condensed chromosome inner kinetochore chromatin binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytosol viral process nucleosomal DNA binding nuclear pericentric heterochromatin CENP-A containing nucleosome assembly protein heterodimerization activity kinetochore assembly protein localization to chromosome, centromeric region |
| NDEx Network | CENPA |
| Atlas of Cancer Signalling Network | CENPA |
| Wikipedia pathways | CENPA |
| Orthology - Evolution |
|---|
| OrthoDB | 1058 |
| GeneTree (enSembl) | ENSG00000115163 |
| Phylogenetic Trees/Animal Genes : TreeFam | CENPA |
| HOGENOM | P49450 |
| Homologs : HomoloGene | CENPA |
| Homology/Alignments : Family Browser (UCSC) | CENPA |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | CENPA |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | CENPA [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | CENPA |
| dbVar | CENPA |
| ClinVar | CENPA |
| 1000_Genomes | CENPA |
| Exome Variant Server | CENPA |
| ExAC (Exome Aggregation Consortium) | ENSG00000115163 |
| GNOMAD Browser | ENSG00000115163 |
| Varsome Browser | CENPA |
| Genetic variants : HAPMAP | 1058 |
| Genomic Variants (DGV) | CENPA [DGVbeta] |
| DECIPHER | CENPA [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | CENPA |
| Mutations |
|---|
| ICGC Data Portal | CENPA |
| TCGA Data Portal | CENPA |
| Broad Tumor Portal | CENPA |
| OASIS Portal | CENPA [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | CENPA [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | CENPA |
| Mutations and Diseases : HGMD | CENPA |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search CENPA |
| DgiDB (Drug Gene Interaction Database) | CENPA |
| DoCM (Curated mutations) | CENPA (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | CENPA (select a term) |
| intoGen | CENPA |
| Cancer3D | CENPA(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 117139 |
| Orphanet | |
| DisGeNET | CENPA |
| Medgen | CENPA |
| Genetic Testing Registry | CENPA
|
| NextProt | P49450 [Medical] |
| TSGene | 1058 |
| GENETests | CENPA |
| Target Validation | CENPA |
| Huge Navigator |
CENPA [HugePedia] |
| snp3D : Map Gene to Disease | 1058 |
| BioCentury BCIQ | CENPA |
| ClinGen | CENPA |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 1058 |
| Chemical/Pharm GKB Gene | PA26396 |
| Clinical trial | CENPA |
| Miscellaneous |
|---|
| canSAR (ICR) | CENPA (select the gene name) |
| DataMed Index | CENPA |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 140 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | CENPA |
| EVEX | CENPA |
| GoPubMed | CENPA |
| iHOP | CENPA |
