CENPB (centromere protein B)

2006-10-01  

Identity

HGNC
LOCATION
20p13
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 1059
MIM: 117140
HGNC: 1852
Ensembl: ENSG00000125817

Variants:

dbSNP: 1059
ClinVar: 1059
TCGA: ENSG00000125817
COSMIC: CENPB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125817ENST00000379751P07199

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
118846092002CENP-A, -B, and -C chromatin complex that contains the I-type alpha-satellite array constitutes the prekinetochore in HeLa cells.65
259426232015DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function.65
172582082007Centromeric protein CENP-B proteasomal degradation induced by the viral protein ICP0.32
146124522004CENP-B interacts with CENP-C domains containing Mif2 regions responsible for centromere localization.25
161836412005Human centromere protein B induces translational positioning of nucleosomes on alpha-satellite sequences.18
259168502015Stable complex formation of CENP-B with the CENP-A nucleosome.18
194129742008Live-cell imaging reveals sustained centromere binding of CENP-T via CENP-A and CENP-B.14
180721842008Assembly of the inner kinetochore proteins CENP-A and CENP-B in living human cells.11
156343502005CpG methylation of the CENP-B box reduces human CENP-B binding.10
224679482012Clinical correlates of CENP-A and CENP-B antibodies in a large cohort of patients with systemic sclerosis.10

Citation

Dessen P

CENPB (centromere protein B)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43207/cenpb