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CENPC (centromere protein C)

Identity

Alias_namesCENPC1
centromere protein C 1
Alias_symbol (synonym)CENP-C
hcp-4
MIF2
Other alias
HGNC (Hugo) CENPC
LocusID (NCBI) 1060
Atlas_Id 55465
Location 4q13.2  [Link to chromosome band 4q13]
Location_base_pair Starts at 67472271 and ends at 67545538 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CENPC (4q13.2) / PAICS (4q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CENPC   1854
Cards
Entrez_Gene (NCBI)CENPC  1060  centromere protein C
AliasesCENP-C; CENPC1; MIF2; hcp-4
GeneCards (Weizmann)CENPC
Ensembl hg19 (Hinxton)ENSG00000145241 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145241 [Gene_View]  chr4:67472271-67545538 [Contig_View]  CENPC [Vega]
ICGC DataPortalENSG00000145241
TCGA cBioPortalCENPC
AceView (NCBI)CENPC
Genatlas (Paris)CENPC
WikiGenes1060
SOURCE (Princeton)CENPC
Genetics Home Reference (NIH)CENPC
Genomic and cartography
GoldenPath hg38 (UCSC)CENPC  -     chr4:67472271-67545538 -  4q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CENPC  -     4q13.2   [Description]    (hg19-Feb_2009)
EnsemblCENPC - 4q13.2 [CytoView hg19]  CENPC - 4q13.2 [CytoView hg38]
Mapping of homologs : NCBICENPC [Mapview hg19]  CENPC [Mapview hg38]
OMIM117141   
Gene and transcription
Genbank (Entrez)AK307928 AK308170 AK308214 AK309437 BC030695
RefSeq transcript (Entrez)NM_001812
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CENPC
Cluster EST : UnigeneHs.479867 [ NCBI ]
CGAP (NCI)Hs.479867
Alternative Splicing GalleryENSG00000145241
Gene ExpressionCENPC [ NCBI-GEO ]   CENPC [ EBI - ARRAY_EXPRESS ]   CENPC [ SEEK ]   CENPC [ MEM ]
Gene Expression Viewer (FireBrowse)CENPC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1060
GTEX Portal (Tissue expression)CENPC
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ03188   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ03188  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ03188
Splice isoforms : SwissVarQ03188
PhosPhoSitePlusQ03188
Domains : Interpro (EBI)CENP-C/Mif2/cnp3    CENP-C_mid    CENP_C_N_dom    Mif2/CENP-C_cupin    RmlC-like_jellyroll    RmlC_Cupin   
Domain families : Pfam (Sanger)CENP-C_C (PF11699)    CENP-C_mid (PF15620)    CENP_C_N (PF15622)   
Domain families : Pfam (NCBI)pfam11699    pfam15620    pfam15622   
Conserved Domain (NCBI)CENPC
DMDM Disease mutations1060
Blocks (Seattle)CENPC
PDB (SRS)5LSJ    5LSK   
PDB (PDBSum)5LSJ    5LSK   
PDB (IMB)5LSJ    5LSK   
PDB (RSDB)5LSJ    5LSK   
Structural Biology KnowledgeBase5LSJ    5LSK   
SCOP (Structural Classification of Proteins)5LSJ    5LSK   
CATH (Classification of proteins structures)5LSJ    5LSK   
SuperfamilyQ03188
Human Protein AtlasENSG00000145241
Peptide AtlasQ03188
HPRD00315
IPIIPI00304885   IPI00966949   IPI00966675   IPI00967987   
Protein Interaction databases
DIP (DOE-UCLA)Q03188
IntAct (EBI)Q03188
FunCoupENSG00000145241
BioGRIDCENPC
STRING (EMBL)CENPC
ZODIACCENPC
Ontologies - Pathways
QuickGOQ03188
Ontology : AmiGOmitotic cell cycle  kinetochore  condensed nuclear chromosome kinetochore  condensed nuclear chromosome, centromeric region  DNA binding  nucleoplasm  nucleoplasm  pericentric heterochromatin  cytosol  cytosol  chromosome segregation  sister chromatid cohesion  nuclear body  centromeric DNA binding  nuclear pericentric heterochromatin  CENP-A containing nucleosome assembly  cell division  attachment of mitotic spindle microtubules to kinetochore  kinetochore assembly  attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation  
Ontology : EGO-EBImitotic cell cycle  kinetochore  condensed nuclear chromosome kinetochore  condensed nuclear chromosome, centromeric region  DNA binding  nucleoplasm  nucleoplasm  pericentric heterochromatin  cytosol  cytosol  chromosome segregation  sister chromatid cohesion  nuclear body  centromeric DNA binding  nuclear pericentric heterochromatin  CENP-A containing nucleosome assembly  cell division  attachment of mitotic spindle microtubules to kinetochore  kinetochore assembly  attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation  
NDEx NetworkCENPC
Atlas of Cancer Signalling NetworkCENPC
Wikipedia pathwaysCENPC
Orthology - Evolution
OrthoDB1060
GeneTree (enSembl)ENSG00000145241
Phylogenetic Trees/Animal Genes : TreeFamCENPC
HOVERGENQ03188
HOGENOMQ03188
Homologs : HomoloGeneCENPC
Homology/Alignments : Family Browser (UCSC)CENPC
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCENPC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CENPC
dbVarCENPC
ClinVarCENPC
1000_GenomesCENPC 
Exome Variant ServerCENPC
ExAC (Exome Aggregation Consortium)CENPC (select the gene name)
Genetic variants : HAPMAP1060
Genomic Variants (DGV)CENPC [DGVbeta]
DECIPHERCENPC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCENPC 
Mutations
ICGC Data PortalCENPC 
TCGA Data PortalCENPC 
Broad Tumor PortalCENPC
OASIS PortalCENPC [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCENPC
BioMutasearch CENPC
DgiDB (Drug Gene Interaction Database)CENPC
DoCM (Curated mutations)CENPC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CENPC (select a term)
intoGenCENPC
Cancer3DCENPC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM117141   
Orphanet
MedgenCENPC
Genetic Testing Registry CENPC
NextProtQ03188 [Medical]
TSGene1060
GENETestsCENPC
Huge Navigator CENPC [HugePedia]
snp3D : Map Gene to Disease1060
BioCentury BCIQCENPC
ClinGenCENPC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1060
Chemical/Pharm GKB GenePA26398
Clinical trialCENPC
Miscellaneous
canSAR (ICR)CENPC (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCENPC
EVEXCENPC
GoPubMedCENPC
iHOPCENPC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:10:10 CEST 2017

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