Identity
HGNC
LOCATION
4q24
LOCUSID
ALIAS
CENP-E,KIF10,MCPH13,PPP1R61
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1062
MIM: 117143
HGNC: 1856
Ensembl: ENSG00000138778
Variants:
dbSNP: 1062
ClinVar: 1062
TCGA: ENSG00000138778
COSMIC: CENPE
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000138778 | ENST00000265148 | Q02224 |
| ENSG00000138778 | ENST00000380026 | Q02224 |
| ENSG00000138778 | ENST00000514974 | D6RHK2 |
| ENSG00000138778 | ENST00000611174 | A0A087X0P0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37934467 | 2024 | A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona. | 2 |
| 38424231 | 2024 | CKAP5 stabilizes CENP-E at kinetochores by regulating microtubule-chromosome attachments. | 1 |
| 37934467 | 2024 | A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona. | 2 |
| 38424231 | 2024 | CKAP5 stabilizes CENP-E at kinetochores by regulating microtubule-chromosome attachments. | 1 |
| 37658044 | 2023 | CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly. | 6 |
| 37658044 | 2023 | CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly. | 6 |
| 33645531 | 2021 | Structure and comparison of the motor domain of centromere-associated protein E. | 1 |
| 33742057 | 2021 | A non-canonical function for Centromere-associated protein-E controls centrosome integrity and orientation of cell division. | 9 |
| 33910471 | 2021 | Poly-SUMO-2/3 chain modification of Nuf2 facilitates CENP-E kinetochore localization and chromosome congression during mitosis. | 3 |
| 34482803 | 2021 | Centromere protein E as a novel biomarker and potential therapeutic target for retinoblastoma. | 9 |
| 33645531 | 2021 | Structure and comparison of the motor domain of centromere-associated protein E. | 1 |
| 33742057 | 2021 | A non-canonical function for Centromere-associated protein-E controls centrosome integrity and orientation of cell division. | 9 |
| 33910471 | 2021 | Poly-SUMO-2/3 chain modification of Nuf2 facilitates CENP-E kinetochore localization and chromosome congression during mitosis. | 3 |
| 34482803 | 2021 | Centromere protein E as a novel biomarker and potential therapeutic target for retinoblastoma. | 9 |
| 31174204 | 2020 | Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly. | 17 |
Citation
Dessen P
CENPE (centromere protein E)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40056/cenpe
