Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CENPJ (centromere protein J)

Identity

Alias_namesMCPH6
microcephaly
Alias_symbol (synonym)CPAP
BM032
LAP
LIP1
Sas-4
SASS4
SCKL4
Other aliasCENP-J
HGNC (Hugo) CENPJ
LocusID (NCBI) 55835
Atlas_Id 40058
Location 13q12.12  [Link to chromosome band 13q12]
Location_base_pair Starts at 24882274 and ends at 24922889 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CENPJ (13q12.12) / PAN3 (13q12.2)PAN3 (13q12.2) / CENPJ (13q12.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CENPJ   17272
Cards
Entrez_Gene (NCBI)CENPJ  55835  centromere protein J
AliasesBM032; CENP-J; CPAP; LAP; 
LIP1; MCPH6; SASS4; SCKL4; Sas-4
GeneCards (Weizmann)CENPJ
Ensembl hg19 (Hinxton)ENSG00000151849 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151849 [Gene_View]  chr13:24882274-24922889 [Contig_View]  CENPJ [Vega]
ICGC DataPortalENSG00000151849
TCGA cBioPortalCENPJ
AceView (NCBI)CENPJ
Genatlas (Paris)CENPJ
WikiGenes55835
SOURCE (Princeton)CENPJ
Genetics Home Reference (NIH)CENPJ
Genomic and cartography
GoldenPath hg38 (UCSC)CENPJ  -     chr13:24882274-24922889 -  13q12.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CENPJ  -     13q12.12   [Description]    (hg19-Feb_2009)
EnsemblCENPJ - 13q12.12 [CytoView hg19]  CENPJ - 13q12.12 [CytoView hg38]
Mapping of homologs : NCBICENPJ [Mapview hg19]  CENPJ [Mapview hg38]
OMIM608393   609279   613676   
Gene and transcription
Genbank (Entrez)AF139625 AF141337 AF141343 AF217509 AJ303006
RefSeq transcript (Entrez)NM_018451
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CENPJ
Cluster EST : UnigeneHs.741581 [ NCBI ]
CGAP (NCI)Hs.741581
Alternative Splicing GalleryENSG00000151849
Gene ExpressionCENPJ [ NCBI-GEO ]   CENPJ [ EBI - ARRAY_EXPRESS ]   CENPJ [ SEEK ]   CENPJ [ MEM ]
Gene Expression Viewer (FireBrowse)CENPJ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55835
GTEX Portal (Tissue expression)CENPJ
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HC77   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HC77  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HC77
Splice isoforms : SwissVarQ9HC77
PhosPhoSitePlusQ9HC77
Domains : Interpro (EBI)CENP-J    Tcp10_C_dom    TCP10_fam   
Domain families : Pfam (Sanger)Tcp10_C (PF07202)   
Domain families : Pfam (NCBI)pfam07202   
Conserved Domain (NCBI)CENPJ
DMDM Disease mutations55835
Blocks (Seattle)CENPJ
PDB (SRS)5EIB    5ITZ   
PDB (PDBSum)5EIB    5ITZ   
PDB (IMB)5EIB    5ITZ   
PDB (RSDB)5EIB    5ITZ   
Structural Biology KnowledgeBase5EIB    5ITZ   
SCOP (Structural Classification of Proteins)5EIB    5ITZ   
CATH (Classification of proteins structures)5EIB    5ITZ   
SuperfamilyQ9HC77
Human Protein AtlasENSG00000151849
Peptide AtlasQ9HC77
HPRD09876
IPIIPI00043201   IPI01009174   IPI01010206   IPI00386218   IPI00386507   
Protein Interaction databases
DIP (DOE-UCLA)Q9HC77
IntAct (EBI)Q9HC77
FunCoupENSG00000151849
BioGRIDCENPJ
STRING (EMBL)CENPJ
ZODIACCENPJ
Ontologies - Pathways
QuickGOQ9HC77
Ontology : AmiGOG2/M transition of mitotic cell cycle  protein binding  nucleoplasm  centrosome  centriole  cytosol  microtubule  plasma membrane  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  microtubule nucleation  centriole replication  smoothened signaling pathway  gamma-tubulin small complex  tubulin binding  protein kinase binding  protein domain specific binding  ciliary basal body  motile cilium assembly  regulation of centriole replication  microtubule polymerization  cell division  centriole elongation  ciliary basal body docking  positive regulation of non-motile cilium assembly  non-motile cilium assembly  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  protein binding  nucleoplasm  centrosome  centriole  cytosol  microtubule  plasma membrane  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  microtubule nucleation  centriole replication  smoothened signaling pathway  gamma-tubulin small complex  tubulin binding  protein kinase binding  protein domain specific binding  ciliary basal body  motile cilium assembly  regulation of centriole replication  microtubule polymerization  cell division  centriole elongation  ciliary basal body docking  positive regulation of non-motile cilium assembly  non-motile cilium assembly  
NDEx NetworkCENPJ
Atlas of Cancer Signalling NetworkCENPJ
Wikipedia pathwaysCENPJ
Orthology - Evolution
OrthoDB55835
GeneTree (enSembl)ENSG00000151849
Phylogenetic Trees/Animal Genes : TreeFamCENPJ
HOVERGENQ9HC77
HOGENOMQ9HC77
Homologs : HomoloGeneCENPJ
Homology/Alignments : Family Browser (UCSC)CENPJ
Gene fusions - Rearrangements
Fusion Cancer (Beijing)CENPJ [13q12.12]  -  PAN3 [13q12.2]  [FUSC000139]
Fusion Cancer (Beijing)PAN3 [13q12.2]  -  CENPJ [13q12.12]  [FUSC000146]  [FUSC000146]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCENPJ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CENPJ
dbVarCENPJ
ClinVarCENPJ
1000_GenomesCENPJ 
Exome Variant ServerCENPJ
ExAC (Exome Aggregation Consortium)CENPJ (select the gene name)
Genetic variants : HAPMAP55835
Genomic Variants (DGV)CENPJ [DGVbeta]
DECIPHERCENPJ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCENPJ 
Mutations
ICGC Data PortalCENPJ 
TCGA Data PortalCENPJ 
Broad Tumor PortalCENPJ
OASIS PortalCENPJ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCENPJ  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCENPJ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CENPJ
DgiDB (Drug Gene Interaction Database)CENPJ
DoCM (Curated mutations)CENPJ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CENPJ (select a term)
intoGenCENPJ
Cancer3DCENPJ(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608393    609279    613676   
Orphanet732    954   
MedgenCENPJ
Genetic Testing Registry CENPJ
NextProtQ9HC77 [Medical]
TSGene55835
GENETestsCENPJ
Target ValidationCENPJ
Huge Navigator CENPJ [HugePedia]
snp3D : Map Gene to Disease55835
BioCentury BCIQCENPJ
ClinGenCENPJ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55835
Chemical/Pharm GKB GenePA26403
Clinical trialCENPJ
Miscellaneous
canSAR (ICR)CENPJ (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCENPJ
EVEXCENPJ
GoPubMedCENPJ
iHOPCENPJ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:57:36 CEST 2017

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