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CENPK (centromere protein K)

Identity

Alias (NCBI)AF5alpha
CENP-K
FKSG14
P33
Solt
HGNC (Hugo) CENPK
HGNC Alias symbFKSG14
SOLT
CENP-K
LocusID (NCBI) 64105
Atlas_Id 52980
Location 5q12.3  [Link to chromosome band 5q12]
Location_base_pair Starts at 65517766 and ends at 65563168 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CENPK (5q12.3) / CCSER1 (4q22.1)CENPK (5q12.3) / CHMP1A (16q24.3)CENPK (5q12.3) / KMT2A (11q23.3)
KMT2A (11q23.3) / CENPK (5q12.3)CENPK 5q12.3 / KMT2A 11q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;11)(q12;q23) CENPK/KMT2A


External links

 

Nomenclature
HGNC (Hugo)CENPK   29479
Cards
Entrez_Gene (NCBI)CENPK    centromere protein K
AliasesAF5alpha; CENP-K; FKSG14; P33; 
Solt
GeneCards (Weizmann)CENPK
Ensembl hg19 (Hinxton)ENSG00000123219 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123219 [Gene_View]  ENSG00000123219 [Sequence]  chr5:65517766-65563168 [Contig_View]  CENPK [Vega]
ICGC DataPortalENSG00000123219
TCGA cBioPortalCENPK
AceView (NCBI)CENPK
Genatlas (Paris)CENPK
SOURCE (Princeton)CENPK
Genetics Home Reference (NIH)CENPK
Genomic and cartography
GoldenPath hg38 (UCSC)CENPK  -     chr5:65517766-65563168 -  5q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CENPK  -     5q12.3   [Description]    (hg19-Feb_2009)
GoldenPathCENPK - 5q12.3 [CytoView hg19]  CENPK - 5q12.3 [CytoView hg38]
ImmunoBaseENSG00000123219
Genome Data Viewer NCBICENPK [Mapview hg19]  
OMIM611502   
Gene and transcription
Genbank (Entrez)AF315941 AY009151 BC005400 BC008504 BF211376
RefSeq transcript (Entrez)NM_001267038 NM_001349367 NM_001349368 NM_001349369 NM_022145
Consensus coding sequences : CCDS (NCBI)CENPK
Gene ExpressionCENPK [ NCBI-GEO ]   CENPK [ EBI - ARRAY_EXPRESS ]   CENPK [ SEEK ]   CENPK [ MEM ]
Gene Expression Viewer (FireBrowse)CENPK [ Firebrowse - Broad ]
GenevisibleExpression of CENPK in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64105
GTEX Portal (Tissue expression)CENPK
Human Protein AtlasENSG00000123219-CENPK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BS16   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BS16  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BS16
PhosPhoSitePlusQ9BS16
Domains : Interpro (EBI)Centromere_CenpK   
Domain families : Pfam (Sanger)CENP-K (PF11802)   
Domain families : Pfam (NCBI)pfam11802   
Conserved Domain (NCBI)CENPK
SuperfamilyQ9BS16
AlphaFold pdb e-kbQ9BS16   
Human Protein Atlas [tissue]ENSG00000123219-CENPK [tissue]
HPRD13323
Protein Interaction databases
DIP (DOE-UCLA)Q9BS16
IntAct (EBI)Q9BS16
BioGRIDCENPK
STRING (EMBL)CENPK
ZODIACCENPK
Ontologies - Pathways
QuickGOQ9BS16
Ontology : AmiGOmitotic sister chromatid segregation  inner kinetochore  protein binding  nucleoplasm  cytosol  mitotic spindle organization  CENP-A containing nucleosome assembly  kinetochore assembly  
Ontology : EGO-EBImitotic sister chromatid segregation  inner kinetochore  protein binding  nucleoplasm  cytosol  mitotic spindle organization  CENP-A containing nucleosome assembly  kinetochore assembly  
NDEx NetworkCENPK
Atlas of Cancer Signalling NetworkCENPK
Wikipedia pathwaysCENPK
Orthology - Evolution
OrthoDB64105
GeneTree (enSembl)ENSG00000123219
Phylogenetic Trees/Animal Genes : TreeFamCENPK
Homologs : HomoloGeneCENPK
Homology/Alignments : Family Browser (UCSC)CENPK
Gene fusions - Rearrangements
Fusion : QuiverCENPK
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCENPK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CENPK
dbVarCENPK
ClinVarCENPK
MonarchCENPK
1000_GenomesCENPK 
Exome Variant ServerCENPK
GNOMAD BrowserENSG00000123219
Varsome BrowserCENPK
ACMGCENPK variants
VarityQ9BS16
Genomic Variants (DGV)CENPK [DGVbeta]
DECIPHERCENPK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCENPK 
Mutations
ICGC Data PortalCENPK 
TCGA Data PortalCENPK 
Broad Tumor PortalCENPK
OASIS PortalCENPK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCENPK  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCENPK
Mutations and Diseases : HGMDCENPK
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCENPK
DgiDB (Drug Gene Interaction Database)CENPK
DoCM (Curated mutations)CENPK
CIViC (Clinical Interpretations of Variants in Cancer)CENPK
Cancer3DCENPK
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611502   
Orphanet
DisGeNETCENPK
MedgenCENPK
Genetic Testing Registry CENPK
NextProtQ9BS16 [Medical]
GENETestsCENPK
Target ValidationCENPK
Huge Navigator CENPK [HugePedia]
ClinGenCENPK
Clinical trials, drugs, therapy
MyCancerGenomeCENPK
Protein Interactions : CTDCENPK
Pharm GKB GenePA145149171
PharosQ9BS16
Clinical trialCENPK
Miscellaneous
canSAR (ICR)CENPK
HarmonizomeCENPK
DataMed IndexCENPK
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCENPK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:03:31 CEST 2021

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