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CENPK (centromere protein K)

Identity

Alias_symbol (synonym)FKSG14
SOLT
CENP-K
Other aliasAF5alpha
P33
Solt
HGNC (Hugo) CENPK
LocusID (NCBI) 64105
Atlas_Id 52980
Location 5q12.3  [Link to chromosome band 5q12]
Location_base_pair Starts at 65517766 and ends at 65563168 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CENPK (5q12.3) / CCSER1 (4q22.1)CENPK (5q12.3) / CHMP1A (16q24.3)CENPK (5q12.3) / KMT2A (11q23.3)
KMT2A (11q23.3) / CENPK (5q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;11)(q12;q23) CENPK/KMT2A


External links

Nomenclature
HGNC (Hugo)CENPK   29479
Cards
Entrez_Gene (NCBI)CENPK  64105  centromere protein K
AliasesAF5alpha; CENP-K; FKSG14; P33; 
Solt
GeneCards (Weizmann)CENPK
Ensembl hg19 (Hinxton)ENSG00000123219 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123219 [Gene_View]  ENSG00000123219 [Sequence]  chr5:65517766-65563168 [Contig_View]  CENPK [Vega]
ICGC DataPortalENSG00000123219
TCGA cBioPortalCENPK
AceView (NCBI)CENPK
Genatlas (Paris)CENPK
WikiGenes64105
SOURCE (Princeton)CENPK
Genetics Home Reference (NIH)CENPK
Genomic and cartography
GoldenPath hg38 (UCSC)CENPK  -     chr5:65517766-65563168 -  5q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CENPK  -     5q12.3   [Description]    (hg19-Feb_2009)
CENPK - 5q12.3 [CytoView hg19]  CENPK - 5q12.3 [CytoView hg38]
Mapping of homologs : NCBICENPK [Mapview hg19]  CENPK [Mapview hg38]
OMIM611502   
Gene and transcription
Genbank (Entrez)AF315941 AY009151 BC005400 BC008504 BF211376
RefSeq transcript (Entrez)NM_001267038 NM_001349367 NM_001349368 NM_001349369 NM_022145
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CENPK
Cluster EST : UnigeneHs.529778 [ NCBI ]
CGAP (NCI)Hs.529778
Alternative Splicing GalleryENSG00000123219
Gene ExpressionCENPK [ NCBI-GEO ]   CENPK [ EBI - ARRAY_EXPRESS ]   CENPK [ SEEK ]   CENPK [ MEM ]
Gene Expression Viewer (FireBrowse)CENPK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64105
GTEX Portal (Tissue expression)CENPK
Human Protein AtlasENSG00000123219-CENPK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BS16   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BS16  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BS16
Splice isoforms : SwissVarQ9BS16
PhosPhoSitePlusQ9BS16
Domains : Interpro (EBI)Centromere_CenpK   
Domain families : Pfam (Sanger)CENP-K (PF11802)   
Domain families : Pfam (NCBI)pfam11802   
Conserved Domain (NCBI)CENPK
DMDM Disease mutations64105
Blocks (Seattle)CENPK
SuperfamilyQ9BS16
Human Protein Atlas [tissue]ENSG00000123219-CENPK [tissue]
Peptide AtlasQ9BS16
HPRD13323
IPIIPI00074020   IPI00967904   IPI00966445   IPI00964367   IPI00964046   IPI00964429   IPI00964073   IPI00967498   
Protein Interaction databases
DIP (DOE-UCLA)Q9BS16
IntAct (EBI)Q9BS16
FunCoupENSG00000123219
BioGRIDCENPK
STRING (EMBL)CENPK
ZODIACCENPK
Ontologies - Pathways
QuickGOQ9BS16
Ontology : AmiGOcondensed chromosome kinetochore  protein binding  nucleoplasm  cytosol  CENP-A containing nucleosome assembly  kinetochore assembly  
Ontology : EGO-EBIcondensed chromosome kinetochore  protein binding  nucleoplasm  cytosol  CENP-A containing nucleosome assembly  kinetochore assembly  
NDEx NetworkCENPK
Atlas of Cancer Signalling NetworkCENPK
Wikipedia pathwaysCENPK
Orthology - Evolution
OrthoDB64105
GeneTree (enSembl)ENSG00000123219
Phylogenetic Trees/Animal Genes : TreeFamCENPK
HOGENOMQ9BS16
Homologs : HomoloGeneCENPK
Homology/Alignments : Family Browser (UCSC)CENPK
Gene fusions - Rearrangements
Fusion : QuiverCENPK
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCENPK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CENPK
dbVarCENPK
ClinVarCENPK
1000_GenomesCENPK 
Exome Variant ServerCENPK
ExAC (Exome Aggregation Consortium)ENSG00000123219
GNOMAD BrowserENSG00000123219
Varsome BrowserCENPK
Genetic variants : HAPMAP64105
Genomic Variants (DGV)CENPK [DGVbeta]
DECIPHERCENPK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCENPK 
Mutations
ICGC Data PortalCENPK 
TCGA Data PortalCENPK 
Broad Tumor PortalCENPK
OASIS PortalCENPK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCENPK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCENPK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CENPK
DgiDB (Drug Gene Interaction Database)CENPK
DoCM (Curated mutations)CENPK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CENPK (select a term)
intoGenCENPK
Cancer3DCENPK(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611502   
Orphanet
DisGeNETCENPK
MedgenCENPK
Genetic Testing Registry CENPK
NextProtQ9BS16 [Medical]
TSGene64105
GENETestsCENPK
Target ValidationCENPK
Huge Navigator CENPK [HugePedia]
snp3D : Map Gene to Disease64105
BioCentury BCIQCENPK
ClinGenCENPK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64105
Chemical/Pharm GKB GenePA145149171
Clinical trialCENPK
Miscellaneous
canSAR (ICR)CENPK (select the gene name)
DataMed IndexCENPK
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCENPK
EVEXCENPK
GoPubMedCENPK
iHOPCENPK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu May 2 12:43:20 CEST 2019

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