CENPL (centromere protein L)

2014-11-01  

Identity

HGNC
LOCATION
1q25.1
LOCUSID
ALIAS
C1orf155,CENP-L,dJ383J4.3
FUSION GENES

Other Information

Locus ID:

NCBI: 91687
MIM: 611503
HGNC: 17879
Ensembl: ENSG00000120334

Variants:

dbSNP: 91687
ClinVar: 91687
TCGA: ENSG00000120334
COSMIC: CENPL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120334ENST00000345664Q8N0S6
ENSG00000120334ENST00000345664A0A024R932
ENSG00000120334ENST00000356198Q8N0S6
ENSG00000120334ENST00000367710Q8N0S6
ENSG00000120334ENST00000367710A0A024R932

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813
Chromosome MaintenanceREACTOMER-HSA-73886
Nucleosome assemblyREACTOMER-HSA-774815
Deposition of new CENPA-containing nucleosomes at the centromereREACTOMER-HSA-606279

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
266986612015The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface.51

Citation

Dessen P

CENPL (centromere protein L)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61706/cenpl