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CEP170 (centrosomal protein 170)

Identity

Alias_namesKIAA0470
KIAA0470
centrosomal protein 170kDa
Alias_symbol (synonym)KAB
FAM68A
Other alias
HGNC (Hugo) CEP170
LocusID (NCBI) 9859
Atlas_Id 54211
Location 1q43  [Link to chromosome band 1q43]
Location_base_pair Starts at 243124428 and ends at 243255406 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AKT3 (1q43) / CEP170 (1q43)CEP170 (1q43) / C1orf100 (1q44)CEP170 (1q43) / IFI16 (1q23.1)
CEP170 (1q43) / RAD51B (14q24.1)CEP170 (1q43) / RGS7 (1q43)CEP170 (1q43) / SDCCAG8 (1q43)
SDCCAG8 (1q43) / CEP170 (1q43)CEP170 1q43 / C1orf100 1q44CEP170 1q43 / IFI16 1q23.1
CEP170 1q43 / RGS7 1q43CEP170 1q43 / SDCCAG8 1q43SDCCAG8 1q43 / CEP170 1q43

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CEP170   28920
Cards
Entrez_Gene (NCBI)CEP170  9859  centrosomal protein 170
AliasesFAM68A; KAB; KIAA0470
GeneCards (Weizmann)CEP170
Ensembl hg19 (Hinxton)ENSG00000143702 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143702 [Gene_View]  chr1:243124428-243255406 [Contig_View]  CEP170 [Vega]
ICGC DataPortalENSG00000143702
TCGA cBioPortalCEP170
AceView (NCBI)CEP170
Genatlas (Paris)CEP170
WikiGenes9859
SOURCE (Princeton)CEP170
Genetics Home Reference (NIH)CEP170
Genomic and cartography
GoldenPath hg38 (UCSC)CEP170  -     chr1:243124428-243255406 -  1q43   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CEP170  -     1q43   [Description]    (hg19-Feb_2009)
EnsemblCEP170 - 1q43 [CytoView hg19]  CEP170 - 1q43 [CytoView hg38]
Mapping of homologs : NCBICEP170 [Mapview hg19]  CEP170 [Mapview hg38]
OMIM613023   
Gene and transcription
Genbank (Entrez)AB007939 AB022657 AB022658 AB022659 AK001664
RefSeq transcript (Entrez)NM_001042404 NM_001042405 NM_014812
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_029663 NT_187519
Consensus coding sequences : CCDS (NCBI)CEP170
Cluster EST : UnigeneHs.533635 [ NCBI ]
CGAP (NCI)Hs.533635
Alternative Splicing GalleryENSG00000143702
Gene ExpressionCEP170 [ NCBI-GEO ]   CEP170 [ EBI - ARRAY_EXPRESS ]   CEP170 [ SEEK ]   CEP170 [ MEM ]
Gene Expression Viewer (FireBrowse)CEP170 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9859
GTEX Portal (Tissue expression)CEP170
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5SW79   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5SW79  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5SW79
Splice isoforms : SwissVarQ5SW79
PhosPhoSitePlusQ5SW79
Domaine pattern : Prosite (Expaxy)FHA_DOMAIN (PS50006)   
Domains : Interpro (EBI)CEP170    CEP170_C    FHA_dom    SMAD_FHA_domain   
Domain families : Pfam (Sanger)CEP170_C (PF15308)    FHA (PF00498)   
Domain families : Pfam (NCBI)pfam15308    pfam00498   
Domain families : Smart (EMBL)FHA (SM00240)  
Conserved Domain (NCBI)CEP170
DMDM Disease mutations9859
Blocks (Seattle)CEP170
PDB (SRS)4JON   
PDB (PDBSum)4JON   
PDB (IMB)4JON   
PDB (RSDB)4JON   
Structural Biology KnowledgeBase4JON   
SCOP (Structural Classification of Proteins)4JON   
CATH (Classification of proteins structures)4JON   
SuperfamilyQ5SW79
Human Protein AtlasENSG00000143702
Peptide AtlasQ5SW79
HPRD17172
IPIIPI00186194   IPI00477477   IPI00871460   IPI00977669   IPI00910412   IPI00647185   IPI01015287   IPI00977139   IPI00981949   IPI00976279   IPI00982512   IPI00983711   IPI00985157   IPI00984576   IPI00973399   IPI00983080   
Protein Interaction databases
DIP (DOE-UCLA)Q5SW79
IntAct (EBI)Q5SW79
FunCoupENSG00000143702
BioGRIDCEP170
STRING (EMBL)CEP170
ZODIACCEP170
Ontologies - Pathways
QuickGOQ5SW79
Ontology : AmiGOprotein binding  centrosome  centriole  spindle  cytosol  microtubule  nuclear membrane  
Ontology : EGO-EBIprotein binding  centrosome  centriole  spindle  cytosol  microtubule  nuclear membrane  
NDEx NetworkCEP170
Atlas of Cancer Signalling NetworkCEP170
Wikipedia pathwaysCEP170
Orthology - Evolution
OrthoDB9859
GeneTree (enSembl)ENSG00000143702
Phylogenetic Trees/Animal Genes : TreeFamCEP170
HOVERGENQ5SW79
HOGENOMQ5SW79
Homologs : HomoloGeneCEP170
Homology/Alignments : Family Browser (UCSC)CEP170
Gene fusions - Rearrangements
Fusion : MitelmanCEP170/IFI16 [1q43/1q23.1]  
Fusion : MitelmanCEP170/RAD51B [1q43/14q24.1]  [t(1;14)(q43;q24)]  
Fusion: TCGACEP170 1q43 C1orf100 1q44 GBM
Fusion: TCGACEP170 1q43 IFI16 1q23.1 PRAD
Fusion: TCGACEP170 1q43 RGS7 1q43 LUAD
Fusion: TCGACEP170 1q43 SDCCAG8 1q43 LUAD
Fusion: TCGASDCCAG8 1q43 CEP170 1q43 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCEP170 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CEP170
dbVarCEP170
ClinVarCEP170
1000_GenomesCEP170 
Exome Variant ServerCEP170
ExAC (Exome Aggregation Consortium)CEP170 (select the gene name)
Genetic variants : HAPMAP9859
Genomic Variants (DGV)CEP170 [DGVbeta]
DECIPHERCEP170 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCEP170 
Mutations
ICGC Data PortalCEP170 
TCGA Data PortalCEP170 
Broad Tumor PortalCEP170
OASIS PortalCEP170 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCEP170  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCEP170
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CEP170
DgiDB (Drug Gene Interaction Database)CEP170
DoCM (Curated mutations)CEP170 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CEP170 (select a term)
intoGenCEP170
Cancer3DCEP170(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613023   
Orphanet
MedgenCEP170
Genetic Testing Registry CEP170
NextProtQ5SW79 [Medical]
TSGene9859
GENETestsCEP170
Target ValidationCEP170
Huge Navigator CEP170 [HugePedia]
snp3D : Map Gene to Disease9859
BioCentury BCIQCEP170
ClinGenCEP170
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9859
Chemical/Pharm GKB GenePA128395757
Clinical trialCEP170
Miscellaneous
canSAR (ICR)CEP170 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCEP170
EVEXCEP170
GoPubMedCEP170
iHOPCEP170
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:28:01 CEST 2017

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