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CEP170B (centrosomal protein 170B)

Identity

Alias (NCBI)CEP170R
FAM68C
KIAA0284
HGNC (Hugo) CEP170B
HGNC Alias symbFAM68C
Cep170R
HGNC Alias nameCep170-related
HGNC Previous nameKIAA0284
HGNC Previous nameKIAA0284
LocusID (NCBI) 283638
Atlas_Id 54065
Location 14q32.33  [Link to chromosome band 14q32]
Location_base_pair Starts at 104865268 and ends at 104896747 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CEP170B (14q32.33) / OLFM2 (19p13.2)ITPK1 (14q32.12) / CEP170B (14q32.33)KMT2A (11q23.3) / CEP170B (14q32.33)
KMT2A 11q23.3 CEP170B

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;14)(q23;q32) KMT2A/CEP170B

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  ITPK1/CEP170B (14q32)

External links

Nomenclature
HGNC (Hugo)CEP170B   20362
Cards
Entrez_Gene (NCBI)CEP170B    centrosomal protein 170B
AliasesCEP170R; FAM68C; KIAA0284
GeneCards (Weizmann)CEP170B
Ensembl hg19 (Hinxton)ENSG00000099814 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099814 [Gene_View]  ENSG00000099814 [Sequence]  chr14:104865268-104896747 [Contig_View]  CEP170B [Vega]
ICGC DataPortalENSG00000099814
TCGA cBioPortalCEP170B
AceView (NCBI)CEP170B
Genatlas (Paris)CEP170B
SOURCE (Princeton)CEP170B
Genetics Home Reference (NIH)CEP170B
Genomic and cartography
GoldenPath hg38 (UCSC)CEP170B  -     chr14:104865268-104896747 +  14q32.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CEP170B  -     14q32.33   [Description]    (hg19-Feb_2009)
GoldenPathCEP170B - 14q32.33 [CytoView hg19]  CEP170B - 14q32.33 [CytoView hg38]
ImmunoBaseENSG00000099814
genome Data Viewer NCBICEP170B [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AA244396 AB006622 AI828210 AK025023 AK091980
RefSeq transcript (Entrez)NM_001112726 NM_015005
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CEP170B
Alternative Splicing GalleryENSG00000099814
Gene ExpressionCEP170B [ NCBI-GEO ]   CEP170B [ EBI - ARRAY_EXPRESS ]   CEP170B [ SEEK ]   CEP170B [ MEM ]
Gene Expression Viewer (FireBrowse)CEP170B [ Firebrowse - Broad ]
GenevisibleExpression of CEP170B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283638
GTEX Portal (Tissue expression)CEP170B
Human Protein AtlasENSG00000099814-CEP170B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4F5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4F5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4F5
Splice isoforms : SwissVarQ9Y4F5
PhosPhoSitePlusQ9Y4F5
Domaine pattern : Prosite (Expaxy)FHA_DOMAIN (PS50006)   
Domains : Interpro (EBI)CEP170_C    FHA_dom    SMAD_FHA_dom_sf   
Domain families : Pfam (Sanger)CEP170_C (PF15308)    FHA (PF00498)   
Domain families : Pfam (NCBI)pfam15308    pfam00498   
Domain families : Smart (EMBL)FHA (SM00240)  
Conserved Domain (NCBI)CEP170B
Blocks (Seattle)CEP170B
SuperfamilyQ9Y4F5
Human Protein Atlas [tissue]ENSG00000099814-CEP170B [tissue]
Peptide AtlasQ9Y4F5
HPRD12388
IPIIPI00180625   IPI00844266   IPI00902841   IPI00942036   IPI01025479   IPI00843802   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4F5
IntAct (EBI)Q9Y4F5
BioGRIDCEP170B
STRING (EMBL)CEP170B
ZODIACCEP170B
Ontologies - Pathways
QuickGOQ9Y4F5
Ontology : AmiGOcytoplasm  microtubule  
Ontology : EGO-EBIcytoplasm  microtubule  
NDEx NetworkCEP170B
Atlas of Cancer Signalling NetworkCEP170B
Wikipedia pathwaysCEP170B
Orthology - Evolution
OrthoDB283638
GeneTree (enSembl)ENSG00000099814
Phylogenetic Trees/Animal Genes : TreeFamCEP170B
HOGENOMQ9Y4F5
Homologs : HomoloGeneCEP170B
Homology/Alignments : Family Browser (UCSC)CEP170B
Gene fusions - Rearrangements
Fusion : MitelmanITPK1/CEP170B [14q32.12/14q32.33]  
Fusion : QuiverCEP170B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCEP170B [hg38]
dbVarCEP170B
ClinVarCEP170B
MonarchCEP170B
1000_GenomesCEP170B 
Exome Variant ServerCEP170B
GNOMAD BrowserENSG00000099814
Varsome BrowserCEP170B
Genomic Variants (DGV)CEP170B [DGVbeta]
DECIPHERCEP170B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCEP170B 
Mutations
ICGC Data PortalCEP170B 
TCGA Data PortalCEP170B 
Broad Tumor PortalCEP170B
OASIS PortalCEP170B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCEP170B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCEP170B
Mutations and Diseases : HGMDCEP170B
BioMutasearch CEP170B
DgiDB (Drug Gene Interaction Database)CEP170B
DoCM (Curated mutations)CEP170B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CEP170B (select a term)
intoGenCEP170B
Cancer3DCEP170B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETCEP170B
MedgenCEP170B
Genetic Testing Registry CEP170B
NextProtQ9Y4F5 [Medical]
GENETestsCEP170B
Target ValidationCEP170B
Huge Navigator CEP170B [HugePedia]
ClinGenCEP170B
Clinical trials, drugs, therapy
MyCancerGenomeCEP170B
Protein Interactions : CTD
Pharm GKB GenePA134863153
PharosQ9Y4F5
Clinical trialCEP170B
Miscellaneous
canSAR (ICR)CEP170B (select the gene name)
HarmonizomeCEP170B
DataMed IndexCEP170B
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCEP170B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri Jan 1 18:09:40 CET 2021
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