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CEP170B (centrosomal protein 170B)

Identity

Alias_namesKIAA0284
KIAA0284
Alias_symbol (synonym)FAM68C
Cep170R
Other aliasCEP170R
HGNC (Hugo) CEP170B
LocusID (NCBI) 283638
Atlas_Id 54065
Location 14q32.33  [Link to chromosome band 14q32]
Location_base_pair Starts at 104865313 and ends at 104896770 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CEP170B (14q32.33) / OLFM2 (19p13.2)ITPK1 (14q32.12) / CEP170B (14q32.33)KMT2A (11q23.3) / CEP170B (14q32.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;14)(q23;q32) KMT2A/CEP170B


External links

Nomenclature
HGNC (Hugo)CEP170B   20362
Cards
Entrez_Gene (NCBI)CEP170B  283638  centrosomal protein 170B
AliasesCEP170R; FAM68C; KIAA0284
GeneCards (Weizmann)CEP170B
Ensembl hg19 (Hinxton)ENSG00000099814 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099814 [Gene_View]  chr14:104865313-104896770 [Contig_View]  CEP170B [Vega]
ICGC DataPortalENSG00000099814
TCGA cBioPortalCEP170B
AceView (NCBI)CEP170B
Genatlas (Paris)CEP170B
WikiGenes283638
SOURCE (Princeton)CEP170B
Genetics Home Reference (NIH)CEP170B
Genomic and cartography
GoldenPath hg38 (UCSC)CEP170B  -     chr14:104865313-104896770 +  14q32.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CEP170B  -     14q32.33   [Description]    (hg19-Feb_2009)
EnsemblCEP170B - 14q32.33 [CytoView hg19]  CEP170B - 14q32.33 [CytoView hg38]
Mapping of homologs : NCBICEP170B [Mapview hg19]  CEP170B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA244396 AB006622 AI828210 AK025023 AK091980
RefSeq transcript (Entrez)NM_001112726 NM_015005
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CEP170B
Cluster EST : UnigeneHs.533721 [ NCBI ]
CGAP (NCI)Hs.533721
Alternative Splicing GalleryENSG00000099814
Gene ExpressionCEP170B [ NCBI-GEO ]   CEP170B [ EBI - ARRAY_EXPRESS ]   CEP170B [ SEEK ]   CEP170B [ MEM ]
Gene Expression Viewer (FireBrowse)CEP170B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283638
GTEX Portal (Tissue expression)CEP170B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4F5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4F5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4F5
Splice isoforms : SwissVarQ9Y4F5
PhosPhoSitePlusQ9Y4F5
Domaine pattern : Prosite (Expaxy)FHA_DOMAIN (PS50006)   
Domains : Interpro (EBI)CEP170_C    FHA_dom    SMAD_FHA_domain   
Domain families : Pfam (Sanger)CEP170_C (PF15308)    FHA (PF00498)   
Domain families : Pfam (NCBI)pfam15308    pfam00498   
Domain families : Smart (EMBL)FHA (SM00240)  
Conserved Domain (NCBI)CEP170B
DMDM Disease mutations283638
Blocks (Seattle)CEP170B
SuperfamilyQ9Y4F5
Human Protein AtlasENSG00000099814
Peptide AtlasQ9Y4F5
HPRD12388
IPIIPI00180625   IPI00844266   IPI00902841   IPI00942036   IPI01025479   IPI00843802   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4F5
IntAct (EBI)Q9Y4F5
FunCoupENSG00000099814
BioGRIDCEP170B
STRING (EMBL)CEP170B
ZODIACCEP170B
Ontologies - Pathways
QuickGOQ9Y4F5
Ontology : AmiGOcytoplasm  microtubule  
Ontology : EGO-EBIcytoplasm  microtubule  
NDEx NetworkCEP170B
Atlas of Cancer Signalling NetworkCEP170B
Wikipedia pathwaysCEP170B
Orthology - Evolution
OrthoDB283638
GeneTree (enSembl)ENSG00000099814
Phylogenetic Trees/Animal Genes : TreeFamCEP170B
HOVERGENQ9Y4F5
HOGENOMQ9Y4F5
Homologs : HomoloGeneCEP170B
Homology/Alignments : Family Browser (UCSC)CEP170B
Gene fusions - Rearrangements
Fusion : MitelmanITPK1/CEP170B [14q32.12/14q32.33]  [t(14;14)(q32;q32)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCEP170B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CEP170B
dbVarCEP170B
ClinVarCEP170B
1000_GenomesCEP170B 
Exome Variant ServerCEP170B
ExAC (Exome Aggregation Consortium)CEP170B (select the gene name)
Genetic variants : HAPMAP283638
Genomic Variants (DGV)CEP170B [DGVbeta]
DECIPHERCEP170B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCEP170B 
Mutations
ICGC Data PortalCEP170B 
TCGA Data PortalCEP170B 
Broad Tumor PortalCEP170B
OASIS PortalCEP170B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCEP170B
BioMutasearch CEP170B
DgiDB (Drug Gene Interaction Database)CEP170B
DoCM (Curated mutations)CEP170B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CEP170B (select a term)
intoGenCEP170B
Cancer3DCEP170B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCEP170B
Genetic Testing Registry CEP170B
NextProtQ9Y4F5 [Medical]
TSGene283638
GENETestsCEP170B
Huge Navigator CEP170B [HugePedia]
snp3D : Map Gene to Disease283638
BioCentury BCIQCEP170B
ClinGenCEP170B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD283638
Chemical/Pharm GKB GenePA134863153
Clinical trialCEP170B
Miscellaneous
canSAR (ICR)CEP170B (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCEP170B
EVEXCEP170B
GoPubMedCEP170B
iHOPCEP170B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:10:13 CEST 2017

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