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CEP57L1 (centrosomal protein 57 like 1)

Identity

Alias_namesC6orf182
chromosome 6 open reading frame 182
centrosomal protein 57kDa-like 1
Alias_symbol (synonym)bA487F23.2
MGC21731
Other aliascep57R
HGNC (Hugo) CEP57L1
LocusID (NCBI) 285753
Atlas_Id 61726
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 109095153 and ends at 109163912 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CEP57L1 (6q21) / CEP57L1 (6q21)SRPK1 (6p21.31) / CEP57L1 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p21;q21) SRPK1/CEP57L1


External links

Nomenclature
HGNC (Hugo)CEP57L1   21561
Cards
Entrez_Gene (NCBI)CEP57L1  285753  centrosomal protein 57 like 1
AliasesC6orf182; bA487F23.2; cep57R
GeneCards (Weizmann)CEP57L1
Ensembl hg19 (Hinxton)ENSG00000183137 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183137 [Gene_View]  ENSG00000183137 [Sequence]  chr6:109095153-109163912 [Contig_View]  CEP57L1 [Vega]
ICGC DataPortalENSG00000183137
TCGA cBioPortalCEP57L1
AceView (NCBI)CEP57L1
Genatlas (Paris)CEP57L1
WikiGenes285753
SOURCE (Princeton)CEP57L1
Genetics Home Reference (NIH)CEP57L1
Genomic and cartography
GoldenPath hg38 (UCSC)CEP57L1  -     chr6:109095153-109163912 +  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CEP57L1  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblCEP57L1 - 6q21 [CytoView hg19]  CEP57L1 - 6q21 [CytoView hg38]
Mapping of homologs : NCBICEP57L1 [Mapview hg19]  CEP57L1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA761530 AK027189 AK092723 AK094192 AK289910
RefSeq transcript (Entrez)NM_001083535 NM_001271852 NM_001271853 NM_001350652 NM_001350653 NM_001350654 NM_001350655 NM_001350656 NM_001350657 NM_001350658 NM_001350659 NM_001350660 NM_001350661 NM_001350662 NM_001350663 NM_001350664 NM_001350665 NM_001350666 NM_173830
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CEP57L1
Cluster EST : UnigeneHs.632616 [ NCBI ]
CGAP (NCI)Hs.632616
Alternative Splicing GalleryENSG00000183137
Gene ExpressionCEP57L1 [ NCBI-GEO ]   CEP57L1 [ EBI - ARRAY_EXPRESS ]   CEP57L1 [ SEEK ]   CEP57L1 [ MEM ]
Gene Expression Viewer (FireBrowse)CEP57L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285753
GTEX Portal (Tissue expression)CEP57L1
Human Protein AtlasENSG00000183137-CEP57L1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYX8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYX8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYX8
Splice isoforms : SwissVarQ8IYX8
PhosPhoSitePlusQ8IYX8
Domains : Interpro (EBI)Cep57_CLD    Cep57_MT-bd_dom   
Domain families : Pfam (Sanger)Cep57_CLD (PF14073)    Cep57_MT_bd (PF06657)   
Domain families : Pfam (NCBI)pfam14073    pfam06657   
Conserved Domain (NCBI)CEP57L1
DMDM Disease mutations285753
Blocks (Seattle)CEP57L1
SuperfamilyQ8IYX8
Human Protein Atlas [tissue]ENSG00000183137-CEP57L1 [tissue]
Peptide AtlasQ8IYX8
HPRD10792
IPIIPI00217914   IPI00977713   IPI00514590   IPI00974304   IPI00973015   IPI00973062   IPI00982709   IPI00978481   IPI00979653   IPI00980150   IPI00980534   IPI00978277   IPI00984859   IPI00982536   IPI00977100   IPI00975870   IPI01018019   IPI00973874   IPI00973981   IPI00977752   IPI00978636   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYX8
IntAct (EBI)Q8IYX8
FunCoupENSG00000183137
BioGRIDCEP57L1
STRING (EMBL)CEP57L1
ZODIACCEP57L1
Ontologies - Pathways
QuickGOQ8IYX8
Ontology : AmiGOmitotic sister chromatid segregation  molecular_function  protein binding  cellular_component  cytoplasm  centrosome  microtubule  microtubule binding  biological_process  identical protein binding  gamma-tubulin binding  
Ontology : EGO-EBImitotic sister chromatid segregation  molecular_function  protein binding  cellular_component  cytoplasm  centrosome  microtubule  microtubule binding  biological_process  identical protein binding  gamma-tubulin binding  
NDEx NetworkCEP57L1
Atlas of Cancer Signalling NetworkCEP57L1
Wikipedia pathwaysCEP57L1
Orthology - Evolution
OrthoDB285753
GeneTree (enSembl)ENSG00000183137
Phylogenetic Trees/Animal Genes : TreeFamCEP57L1
HOVERGENQ8IYX8
HOGENOMQ8IYX8
Homologs : HomoloGeneCEP57L1
Homology/Alignments : Family Browser (UCSC)CEP57L1
Gene fusions - Rearrangements
Fusion : QuiverCEP57L1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCEP57L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CEP57L1
dbVarCEP57L1
ClinVarCEP57L1
1000_GenomesCEP57L1 
Exome Variant ServerCEP57L1
ExAC (Exome Aggregation Consortium)ENSG00000183137
GNOMAD BrowserENSG00000183137
Varsome BrowserCEP57L1
Genetic variants : HAPMAP285753
Genomic Variants (DGV)CEP57L1 [DGVbeta]
DECIPHERCEP57L1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCEP57L1 
Mutations
ICGC Data PortalCEP57L1 
TCGA Data PortalCEP57L1 
Broad Tumor PortalCEP57L1
OASIS PortalCEP57L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCEP57L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCEP57L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CEP57L1
DgiDB (Drug Gene Interaction Database)CEP57L1
DoCM (Curated mutations)CEP57L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CEP57L1 (select a term)
intoGenCEP57L1
Cancer3DCEP57L1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETCEP57L1
MedgenCEP57L1
Genetic Testing Registry CEP57L1
NextProtQ8IYX8 [Medical]
TSGene285753
GENETestsCEP57L1
Target ValidationCEP57L1
Huge Navigator CEP57L1 [HugePedia]
snp3D : Map Gene to Disease285753
BioCentury BCIQCEP57L1
ClinGenCEP57L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD285753
Chemical/Pharm GKB GenePA134980921
Clinical trialCEP57L1
Miscellaneous
canSAR (ICR)CEP57L1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCEP57L1
EVEXCEP57L1
GoPubMedCEP57L1
iHOPCEP57L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Jul 30 13:40:22 CEST 2018

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