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CEP89 (centrosomal protein 89)

Identity

Alias_namesCCDC123
coiled-coil domain containing 123
centrosomal protein 89kDa
Alias_symbol (synonym)FLJ14640
Other aliasCEP123
HGNC (Hugo) CEP89
LocusID (NCBI) 84902
Atlas_Id 55058
Location 19q13.11  [Link to chromosome band 19q13]
Location_base_pair Starts at 32878998 and ends at 32972029 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CEP89 (19q13.11) / BRAF (7q34)CEP89 (19q13.11) / PEPD (19q13.11)KLHL24 (3q27.1) / CEP89 (19q13.11)
CEP89 19q13.11 / BRAF 7q34KLHL24 3q27.1 / CEP89 19q13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CEP89   25907
Cards
Entrez_Gene (NCBI)CEP89  84902  centrosomal protein 89
AliasesCCDC123; CEP123
GeneCards (Weizmann)CEP89
Ensembl hg19 (Hinxton)ENSG00000121289 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121289 [Gene_View]  chr19:32878998-32972029 [Contig_View]  CEP89 [Vega]
ICGC DataPortalENSG00000121289
TCGA cBioPortalCEP89
AceView (NCBI)CEP89
Genatlas (Paris)CEP89
WikiGenes84902
SOURCE (Princeton)CEP89
Genetics Home Reference (NIH)CEP89
Genomic and cartography
GoldenPath hg38 (UCSC)CEP89  -     chr19:32878998-32972029 -  19q13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CEP89  -     19q13.11   [Description]    (hg19-Feb_2009)
EnsemblCEP89 - 19q13.11 [CytoView hg19]  CEP89 - 19q13.11 [CytoView hg38]
Mapping of homologs : NCBICEP89 [Mapview hg19]  CEP89 [Mapview hg38]
OMIM615470   
Gene and transcription
Genbank (Entrez)AK001375 AK027546 AL832158 BC020195 BC029978
RefSeq transcript (Entrez)NM_032816
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CEP89
Cluster EST : UnigeneHs.599703 [ NCBI ]
CGAP (NCI)Hs.599703
Alternative Splicing GalleryENSG00000121289
Gene ExpressionCEP89 [ NCBI-GEO ]   CEP89 [ EBI - ARRAY_EXPRESS ]   CEP89 [ SEEK ]   CEP89 [ MEM ]
Gene Expression Viewer (FireBrowse)CEP89 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84902
GTEX Portal (Tissue expression)CEP89
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96ST8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96ST8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96ST8
Splice isoforms : SwissVarQ96ST8
PhosPhoSitePlusQ96ST8
Domains : Interpro (EBI)CEP89   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CEP89
DMDM Disease mutations84902
Blocks (Seattle)CEP89
SuperfamilyQ96ST8
Human Protein AtlasENSG00000121289
Peptide AtlasQ96ST8
HPRD08601
IPIIPI00939566   IPI00792009   IPI00871895   IPI00382946   
Protein Interaction databases
DIP (DOE-UCLA)Q96ST8
IntAct (EBI)Q96ST8
FunCoupENSG00000121289
BioGRIDCEP89
STRING (EMBL)CEP89
ZODIACCEP89
Ontologies - Pathways
QuickGOQ96ST8
Ontology : AmiGOspindle pole  protein binding  mitochondrial intermembrane space  centrosome  centriole  cytosol  cytosol  plasma membrane  mitochondrion organization  chemical synaptic transmission  motile cilium  cilium assembly  ciliary transition fiber  ciliary basal body docking  non-motile cilium  non-motile cilium assembly  
Ontology : EGO-EBIspindle pole  protein binding  mitochondrial intermembrane space  centrosome  centriole  cytosol  cytosol  plasma membrane  mitochondrion organization  chemical synaptic transmission  motile cilium  cilium assembly  ciliary transition fiber  ciliary basal body docking  non-motile cilium  non-motile cilium assembly  
NDEx NetworkCEP89
Atlas of Cancer Signalling NetworkCEP89
Wikipedia pathwaysCEP89
Orthology - Evolution
OrthoDB84902
GeneTree (enSembl)ENSG00000121289
Phylogenetic Trees/Animal Genes : TreeFamCEP89
HOVERGENQ96ST8
HOGENOMQ96ST8
Homologs : HomoloGeneCEP89
Homology/Alignments : Family Browser (UCSC)CEP89
Gene fusions - Rearrangements
Fusion : MitelmanKLHL24/CEP89 [3q27.1/19q13.11]  [t(3;19)(q27;q13)]  
Fusion: TCGAKLHL24 3q27.1 CEP89 19q13.11 LUSC
Fusion Cancer (Beijing)CEP89 [19q13.11]  -  PEPD [19q13.11]  [FUSC001271]  [FUSC001271]  [FUSC001271]  [FUSC001271]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCEP89 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CEP89
dbVarCEP89
ClinVarCEP89
1000_GenomesCEP89 
Exome Variant ServerCEP89
ExAC (Exome Aggregation Consortium)CEP89 (select the gene name)
Genetic variants : HAPMAP84902
Genomic Variants (DGV)CEP89 [DGVbeta]
DECIPHERCEP89 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCEP89 
Mutations
ICGC Data PortalCEP89 
TCGA Data PortalCEP89 
Broad Tumor PortalCEP89
OASIS PortalCEP89 [ Somatic mutations - Copy number]
Cancer Gene: CensusCEP89 
Somatic Mutations in Cancer : COSMICCEP89  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCEP89
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CEP89
DgiDB (Drug Gene Interaction Database)CEP89
DoCM (Curated mutations)CEP89 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CEP89 (select a term)
intoGenCEP89
Cancer3DCEP89(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615470   
Orphanet
MedgenCEP89
Genetic Testing Registry CEP89
NextProtQ96ST8 [Medical]
TSGene84902
GENETestsCEP89
Target ValidationCEP89
Huge Navigator CEP89 [HugePedia]
snp3D : Map Gene to Disease84902
BioCentury BCIQCEP89
ClinGenCEP89
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84902
Chemical/Pharm GKB GenePA147358250
Clinical trialCEP89
Miscellaneous
canSAR (ICR)CEP89 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCEP89
EVEXCEP89
GoPubMedCEP89
iHOPCEP89
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:28:03 CEST 2017

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