Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CEP89 (centrosomal protein 89)

Identity

Alias (NCBI)CCDC123
CEP123
HGNC (Hugo) CEP89
HGNC Alias symbFLJ14640
HGNC Previous nameCCDC123
HGNC Previous namecoiled-coil domain containing 123
 centrosomal protein 89kDa
LocusID (NCBI) 84902
Atlas_Id 55058
Location 19q13.11  [Link to chromosome band 19q13]
Location_base_pair Starts at 32875925 and ends at 32971958 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CEP89 (19q13.11)::BRAF (7q34)CEP89 (19q13.11)::PEPD (19q13.11)KLHL24 (3q27.1)::CEP89 (19q13.11)
CEP89 19q13.11::BRAF 7q34KLHL24 3q27.1::CEP89 19q13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CEP89   25907
Cards
Entrez_Gene (NCBI)CEP89    centrosomal protein 89
AliasesCCDC123; CEP123
GeneCards (Weizmann)CEP89
Ensembl hg19 (Hinxton)ENSG00000121289 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121289 [Gene_View]  ENSG00000121289 [Sequence]  chr19:32875925-32971958 [Contig_View]  CEP89 [Vega]
ICGC DataPortalENSG00000121289
TCGA cBioPortalCEP89
AceView (NCBI)CEP89
Genatlas (Paris)CEP89
SOURCE (Princeton)CEP89
Genetics Home Reference (NIH)CEP89
Genomic and cartography
GoldenPath hg38 (UCSC)CEP89  -     chr19:32875925-32971958 -  19q13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CEP89  -     19q13.11   [Description]    (hg19-Feb_2009)
GoldenPathCEP89 - 19q13.11 [CytoView hg19]  CEP89 - 19q13.11 [CytoView hg38]
ImmunoBaseENSG00000121289
Genome Data Viewer NCBICEP89 [Mapview hg19]  
OMIM615470   
Gene and transcription
Genbank (Entrez)AK001375 AK027546 AL832158 BC020195 BC029978
RefSeq transcript (Entrez)NM_032816
Consensus coding sequences : CCDS (NCBI)CEP89
Gene ExpressionCEP89 [ NCBI-GEO ]   CEP89 [ EBI - ARRAY_EXPRESS ]   CEP89 [ SEEK ]   CEP89 [ MEM ]
Gene Expression Viewer (FireBrowse)CEP89 [ Firebrowse - Broad ]
GenevisibleExpression of CEP89 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84902
GTEX Portal (Tissue expression)CEP89
Human Protein AtlasENSG00000121289-CEP89 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96ST8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96ST8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96ST8
PhosPhoSitePlusQ96ST8
Domains : Interpro (EBI)CEP89   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CEP89
SuperfamilyQ96ST8
AlphaFold pdb e-kbQ96ST8   
Human Protein Atlas [tissue]ENSG00000121289-CEP89 [tissue]
HPRD08601
Protein Interaction databases
DIP (DOE-UCLA)Q96ST8
IntAct (EBI)Q96ST8
BioGRIDCEP89
STRING (EMBL)CEP89
ZODIACCEP89
Ontologies - Pathways
QuickGOQ96ST8
Ontology : AmiGOspindle pole  protein binding  mitochondrial intermembrane space  centrosome  centriole  centriole  cytosol  cytosol  plasma membrane  mitochondrion organization  chemical synaptic transmission  motile cilium  synapse  cilium assembly  cilium assembly  cilium assembly  ciliary transition fiber  ciliary transition fiber  non-motile cilium  non-motile cilium assembly  
Ontology : EGO-EBIspindle pole  protein binding  mitochondrial intermembrane space  centrosome  centriole  centriole  cytosol  cytosol  plasma membrane  mitochondrion organization  chemical synaptic transmission  motile cilium  synapse  cilium assembly  cilium assembly  cilium assembly  ciliary transition fiber  ciliary transition fiber  non-motile cilium  non-motile cilium assembly  
NDEx NetworkCEP89
Atlas of Cancer Signalling NetworkCEP89
Wikipedia pathwaysCEP89
Orthology - Evolution
OrthoDB84902
GeneTree (enSembl)ENSG00000121289
Phylogenetic Trees/Animal Genes : TreeFamCEP89
Homologs : HomoloGeneCEP89
Homology/Alignments : Family Browser (UCSC)CEP89
Gene fusions - Rearrangements
Fusion : MitelmanKLHL24::CEP89 [3q27.1/19q13.11]  
Fusion Cancer (Beijing)CEP89 [19q13.11]  -  PEPD [19q13.11]  [FUSC001271]  [FUSC001271]  [FUSC001271]  [FUSC001271]
Fusion : QuiverCEP89
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCEP89 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CEP89
dbVarCEP89
ClinVarCEP89
MonarchCEP89
1000_GenomesCEP89 
Exome Variant ServerCEP89
GNOMAD BrowserENSG00000121289
Varsome BrowserCEP89
ACMGCEP89 variants
VarityQ96ST8
Genomic Variants (DGV)CEP89 [DGVbeta]
DECIPHERCEP89 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCEP89 
Mutations
ICGC Data PortalCEP89 
TCGA Data PortalCEP89 
Broad Tumor PortalCEP89
OASIS PortalCEP89 [ Somatic mutations - Copy number]
Cancer Gene: CensusCEP89 
Somatic Mutations in Cancer : COSMICCEP89  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCEP89
Mutations and Diseases : HGMDCEP89
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCEP89
DgiDB (Drug Gene Interaction Database)CEP89
DoCM (Curated mutations)CEP89
CIViC (Clinical Interpretations of Variants in Cancer)CEP89
Cancer3DCEP89
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615470   
Orphanet
DisGeNETCEP89
MedgenCEP89
Genetic Testing Registry CEP89
NextProtQ96ST8 [Medical]
GENETestsCEP89
Target ValidationCEP89
Huge Navigator CEP89 [HugePedia]
ClinGenCEP89
Clinical trials, drugs, therapy
MyCancerGenomeCEP89
Protein Interactions : CTDCEP89
Pharm GKB GenePA147358250
PharosQ96ST8
Clinical trialCEP89
Miscellaneous
canSAR (ICR)CEP89
HarmonizomeCEP89
ARCHS4CEP89
DataMed IndexCEP89
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCEP89
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 12:27:09 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.