Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CETN2 (centrin 2)

Identity

Alias (NCBI)CALT
CEN2
HGNC (Hugo) CETN2
HGNC Alias symbCEN2
HGNC Previous nameCALT
HGNC Previous namecentrin, EF-hand protein, 2
LocusID (NCBI) 1069
Atlas_Id 40062
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 152826994 and ends at 152830757 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CETN2   1867
Cards
Entrez_Gene (NCBI)CETN2    centrin 2
AliasesCALT; CEN2
GeneCards (Weizmann)CETN2
Ensembl hg19 (Hinxton)ENSG00000147400 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147400 [Gene_View]  ENSG00000147400 [Sequence]  chrX:152826994-152830757 [Contig_View]  CETN2 [Vega]
ICGC DataPortalENSG00000147400
TCGA cBioPortalCETN2
AceView (NCBI)CETN2
Genatlas (Paris)CETN2
SOURCE (Princeton)CETN2
Genetics Home Reference (NIH)CETN2
Genomic and cartography
GoldenPath hg38 (UCSC)CETN2  -     chrX:152826994-152830757 -  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CETN2  -     Xq28   [Description]    (hg19-Feb_2009)
GoldenPathCETN2 - Xq28 [CytoView hg19]  CETN2 - Xq28 [CytoView hg38]
ImmunoBaseENSG00000147400
Genome Data Viewer NCBICETN2 [Mapview hg19]  
OMIM300006   
Gene and transcription
Genbank (Entrez)AK311940 BC005334 BC013873 BT007256 X72964
RefSeq transcript (Entrez)NM_004344
Consensus coding sequences : CCDS (NCBI)CETN2
Gene ExpressionCETN2 [ NCBI-GEO ]   CETN2 [ EBI - ARRAY_EXPRESS ]   CETN2 [ SEEK ]   CETN2 [ MEM ]
Gene Expression Viewer (FireBrowse)CETN2 [ Firebrowse - Broad ]
GenevisibleExpression of CETN2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1069
GTEX Portal (Tissue expression)CETN2
Human Protein AtlasENSG00000147400-CETN2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41208   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41208  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41208
PhosPhoSitePlusP41208
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)Centrin_2    EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    RNA-helicase_DEAD-box_CS   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam13499   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)CETN2
PDB (RSDB)1M39    1ZMZ    2A4J    2GGM    2K2I    2OBH   
PDB Europe1M39    1ZMZ    2A4J    2GGM    2K2I    2OBH   
PDB (PDBSum)1M39    1ZMZ    2A4J    2GGM    2K2I    2OBH   
PDB (IMB)1M39    1ZMZ    2A4J    2GGM    2K2I    2OBH   
Structural Biology KnowledgeBase1M39    1ZMZ    2A4J    2GGM    2K2I    2OBH   
SCOP (Structural Classification of Proteins)1M39    1ZMZ    2A4J    2GGM    2K2I    2OBH   
CATH (Classification of proteins structures)1M39    1ZMZ    2A4J    2GGM    2K2I    2OBH   
SuperfamilyP41208
AlphaFold pdb e-kbP41208   
Human Protein Atlas [tissue]ENSG00000147400-CETN2 [tissue]
HPRD02051
Protein Interaction databases
DIP (DOE-UCLA)P41208
IntAct (EBI)P41208
BioGRIDCETN2
STRING (EMBL)CETN2
ZODIACCETN2
Ontologies - Pathways
QuickGOP41208
Ontology : AmiGOG2/M transition of mitotic cell cycle  mitotic cell cycle  mitotic cell cycle  nucleotide-excision repair, DNA damage recognition  nucleotide-excision repair, DNA duplex unwinding  calcium ion binding  calcium ion binding  protein binding  nucleoplasm  centrosome  centrosome  centrosome  centriole  centriole  cytosol  nucleotide-excision repair  nucleotide-excision repair  nucleotide-excision repair, preincision complex assembly  centriole replication  centriole replication  spermatogenesis  microtubule binding  regulation of G2/M transition of mitotic cell cycle  protein transport  G-protein beta/gamma-subunit complex binding  photoreceptor connecting cilium  regulation of cytokinesis  heterotrimeric G-protein binding  ciliary basal body  nuclear pore nuclear basket  apical part of cell  mRNA transport  cell division  transcription export complex 2  global genome nucleotide-excision repair  XPC complex  ciliary basal body-plasma membrane docking  9+2 motile cilium  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  mitotic cell cycle  mitotic cell cycle  nucleotide-excision repair, DNA damage recognition  nucleotide-excision repair, DNA duplex unwinding  calcium ion binding  calcium ion binding  protein binding  nucleoplasm  centrosome  centrosome  centrosome  centriole  centriole  cytosol  nucleotide-excision repair  nucleotide-excision repair  nucleotide-excision repair, preincision complex assembly  centriole replication  centriole replication  spermatogenesis  microtubule binding  regulation of G2/M transition of mitotic cell cycle  protein transport  G-protein beta/gamma-subunit complex binding  photoreceptor connecting cilium  regulation of cytokinesis  heterotrimeric G-protein binding  ciliary basal body  nuclear pore nuclear basket  apical part of cell  mRNA transport  cell division  transcription export complex 2  global genome nucleotide-excision repair  XPC complex  ciliary basal body-plasma membrane docking  9+2 motile cilium  
Pathways : KEGGNucleotide excision repair   
NDEx NetworkCETN2
Atlas of Cancer Signalling NetworkCETN2
Wikipedia pathwaysCETN2
Orthology - Evolution
OrthoDB1069
GeneTree (enSembl)ENSG00000147400
Phylogenetic Trees/Animal Genes : TreeFamCETN2
Homologs : HomoloGeneCETN2
Homology/Alignments : Family Browser (UCSC)CETN2
Gene fusions - Rearrangements
Fusion : QuiverCETN2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCETN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CETN2
dbVarCETN2
ClinVarCETN2
MonarchCETN2
1000_GenomesCETN2 
Exome Variant ServerCETN2
GNOMAD BrowserENSG00000147400
Varsome BrowserCETN2
ACMGCETN2 variants
VarityP41208
Genomic Variants (DGV)CETN2 [DGVbeta]
DECIPHERCETN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCETN2 
Mutations
ICGC Data PortalCETN2 
TCGA Data PortalCETN2 
Broad Tumor PortalCETN2
OASIS PortalCETN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCETN2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCETN2
Mutations and Diseases : HGMDCETN2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCETN2
DgiDB (Drug Gene Interaction Database)CETN2
DoCM (Curated mutations)CETN2
CIViC (Clinical Interpretations of Variants in Cancer)CETN2
Cancer3DCETN2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300006   
Orphanet
DisGeNETCETN2
MedgenCETN2
Genetic Testing Registry CETN2
NextProtP41208 [Medical]
GENETestsCETN2
Target ValidationCETN2
Huge Navigator CETN2 [HugePedia]
ClinGenCETN2
Clinical trials, drugs, therapy
MyCancerGenomeCETN2
Protein Interactions : CTDCETN2
Pharm GKB GenePA26420
PharosP41208
Clinical trialCETN2
Miscellaneous
canSAR (ICR)CETN2
HarmonizomeCETN2
DataMed IndexCETN2
Probes
Litterature
PubMed97 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCETN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:03:40 CEST 2021

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