Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CFD (complement factor D)

Identity

Alias_namesDF
PFD
D component of complement (adipsin)
properdin factor D
complement factor D (adipsin)
Alias_symbol (synonym)ADN
Other aliasADIPSIN
HGNC (Hugo) CFD
LocusID (NCBI) 1675
Atlas_Id 61770
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 859659 and ends at 863569 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CFD (19p13.3) / MED16 (19p13.3)RPS20 (8q12.1) / CFD (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CFD   2771
LRG (Locus Reference Genomic)LRG_46
Cards
Entrez_Gene (NCBI)CFD  1675  complement factor D
AliasesADIPSIN; ADN; DF; PFD
GeneCards (Weizmann)CFD
Ensembl hg19 (Hinxton)ENSG00000197766 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197766 [Gene_View]  chr19:859659-863569 [Contig_View]  CFD [Vega]
ICGC DataPortalENSG00000197766
TCGA cBioPortalCFD
AceView (NCBI)CFD
Genatlas (Paris)CFD
WikiGenes1675
SOURCE (Princeton)CFD
Genetics Home Reference (NIH)CFD
Genomic and cartography
GoldenPath hg38 (UCSC)CFD  -     chr19:859659-863569 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CFD  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblCFD - 19p13.3 [CytoView hg19]  CFD - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBICFD [Mapview hg19]  CFD [Mapview hg38]
OMIM134350   613912   
Gene and transcription
Genbank (Entrez)AJ313463 AK300963 BC034529 BC040146 BC051001
RefSeq transcript (Entrez)NM_001317335 NM_001928
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_007274 NT_187622
Consensus coding sequences : CCDS (NCBI)CFD
Cluster EST : UnigeneHs.155597 [ NCBI ]
CGAP (NCI)Hs.155597
Alternative Splicing GalleryENSG00000197766
Gene ExpressionCFD [ NCBI-GEO ]   CFD [ EBI - ARRAY_EXPRESS ]   CFD [ SEEK ]   CFD [ MEM ]
Gene Expression Viewer (FireBrowse)CFD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1675
GTEX Portal (Tissue expression)CFD
Protein : pattern, domain, 3D structure
UniProt/SwissProtP00746   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP00746  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP00746
Splice isoforms : SwissVarP00746
Catalytic activity : Enzyme3.4.21.46 [ Enzyme-Expasy ]   3.4.21.463.4.21.46 [ IntEnz-EBI ]   3.4.21.46 [ BRENDA ]   3.4.21.46 [ KEGG ]   
PhosPhoSitePlusP00746
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)CFD
DMDM Disease mutations1675
Blocks (Seattle)CFD
PDB (SRS)1BIO    1DFP    1DIC    1DST    1DSU    1FDP    1HFD    2XW9    2XWA    2XWB    4CBN    4CBO    4D9R    5FBE    5FBI    5FCK    5TCA    5TCC   
PDB (PDBSum)1BIO    1DFP    1DIC    1DST    1DSU    1FDP    1HFD    2XW9    2XWA    2XWB    4CBN    4CBO    4D9R    5FBE    5FBI    5FCK    5TCA    5TCC   
PDB (IMB)1BIO    1DFP    1DIC    1DST    1DSU    1FDP    1HFD    2XW9    2XWA    2XWB    4CBN    4CBO    4D9R    5FBE    5FBI    5FCK    5TCA    5TCC   
PDB (RSDB)1BIO    1DFP    1DIC    1DST    1DSU    1FDP    1HFD    2XW9    2XWA    2XWB    4CBN    4CBO    4D9R    5FBE    5FBI    5FCK    5TCA    5TCC   
Structural Biology KnowledgeBase1BIO    1DFP    1DIC    1DST    1DSU    1FDP    1HFD    2XW9    2XWA    2XWB    4CBN    4CBO    4D9R    5FBE    5FBI    5FCK    5TCA    5TCC   
SCOP (Structural Classification of Proteins)1BIO    1DFP    1DIC    1DST    1DSU    1FDP    1HFD    2XW9    2XWA    2XWB    4CBN    4CBO    4D9R    5FBE    5FBI    5FCK    5TCA    5TCC   
CATH (Classification of proteins structures)1BIO    1DFP    1DIC    1DST    1DSU    1FDP    1HFD    2XW9    2XWA    2XWB    4CBN    4CBO    4D9R    5FBE    5FBI    5FCK    5TCA    5TCC   
SuperfamilyP00746
Human Protein AtlasENSG00000197766
Peptide AtlasP00746
HPRD00600
IPIIPI00165972   
Protein Interaction databases
DIP (DOE-UCLA)P00746
IntAct (EBI)P00746
FunCoupENSG00000197766
BioGRIDCFD
STRING (EMBL)CFD
ZODIACCFD
Ontologies - Pathways
QuickGOP00746
Ontology : AmiGOplatelet degranulation  serine-type endopeptidase activity  extracellular region  proteolysis  complement activation  complement activation, alternative pathway  serine-type peptidase activity  platelet alpha granule lumen  secretory granule lumen  neutrophil degranulation  extracellular exosome  ficolin-1-rich granule lumen  
Ontology : EGO-EBIplatelet degranulation  serine-type endopeptidase activity  extracellular region  proteolysis  complement activation  complement activation, alternative pathway  serine-type peptidase activity  platelet alpha granule lumen  secretory granule lumen  neutrophil degranulation  extracellular exosome  ficolin-1-rich granule lumen  
Pathways : BIOCARTAAlternative Complement Pathway [Genes]    Complement Pathway [Genes]   
Pathways : KEGGComplement and coagulation cascades    Staphylococcus aureus infection   
NDEx NetworkCFD
Atlas of Cancer Signalling NetworkCFD
Wikipedia pathwaysCFD
Orthology - Evolution
OrthoDB1675
GeneTree (enSembl)ENSG00000197766
Phylogenetic Trees/Animal Genes : TreeFamCFD
HOVERGENP00746
HOGENOMP00746
Homologs : HomoloGeneCFD
Homology/Alignments : Family Browser (UCSC)CFD
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCFD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CFD
dbVarCFD
ClinVarCFD
1000_GenomesCFD 
Exome Variant ServerCFD
ExAC (Exome Aggregation Consortium)CFD (select the gene name)
Genetic variants : HAPMAP1675
Genomic Variants (DGV)CFD [DGVbeta]
DECIPHERCFD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCFD 
Mutations
ICGC Data PortalCFD 
TCGA Data PortalCFD 
Broad Tumor PortalCFD
OASIS PortalCFD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCFD  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCFD
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch CFD
DgiDB (Drug Gene Interaction Database)CFD
DoCM (Curated mutations)CFD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CFD (select a term)
intoGenCFD
Cancer3DCFD(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM134350    613912   
Orphanet17864   
MedgenCFD
Genetic Testing Registry CFD
NextProtP00746 [Medical]
TSGene1675
GENETestsCFD
Target ValidationCFD
Huge Navigator CFD [HugePedia]
snp3D : Map Gene to Disease1675
BioCentury BCIQCFD
ClinGenCFD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1675
Chemical/Pharm GKB GenePA142
Clinical trialCFD
Miscellaneous
canSAR (ICR)CFD (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCFD
EVEXCFD
GoPubMedCFD
iHOPCFD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:43:28 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.