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CH25H (cholesterol 25-hydroxylase)

Identity

Other aliasC25H
HGNC (Hugo) CH25H
LocusID (NCBI) 9023
Atlas_Id 61784
Location 10q23.31  [Link to chromosome band 10q23]
Location_base_pair Starts at 89205937 and ends at 89207314 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

8TR>Chemical/Pharm GKB Gene
Nomenclature
HGNC (Hugo)CH25H   1907
Cards
Entrez_Gene (NCBI)CH25H  9023  cholesterol 25-hydroxylase
AliasesC25H
GeneCards (Weizmann)CH25H
Ensembl hg19 (Hinxton)ENSG00000138135 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138135 [Gene_View]  chr10:89205937-89207314 [Contig_View]  CH25H [Vega]
ICGC DataPortalENSG00000138135
TCGA cBioPortalCH25H
AceView (NCBI)CH25H
Genatlas (Paris)CH25H
WikiGenes9023
SOURCE (Princeton)CH25H
Genetics Home Reference (NIH)CH25H
Genomic and cartography
GoldenPath hg38 (UCSC)CH25H  -     chr10:89205937-89207314 -  10q23.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CH25H  -     10q23.31   [Description]    (hg19-Feb_2009)
EnsemblCH25H - 10q23.31 [CytoView hg19]  CH25H - 10q23.31 [CytoView hg38]
Mapping of homologs : NCBICH25H [Mapview hg19]  CH25H [Mapview hg38]
OMIM604551   
Gene and transcription
Genbank (Entrez)AF059214 AK314865 BC017843 BC072430 DQ892026
RefSeq transcript (Entrez)NM_003956
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CH25H
Cluster EST : UnigeneHs.47357 [ NCBI ]
CGAP (NCI)Hs.47357
Alternative Splicing GalleryENSG00000138135
Gene ExpressionCH25H [ NCBI-GEO ]   CH25H [ EBI - ARRAY_EXPRESS ]   CH25H [ SEEK ]   CH25H [ MEM ]
Gene Expression Viewer (FireBrowse)CH25H [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9023
GTEX Portal (Tissue expression)CH25H
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95992   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95992  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95992
Splice isoforms : SwissVarO95992
Catalytic activity : Enzyme1.14.99.38 [ Enzyme-Expasy ]   1.14.99.381.14.99.38 [ IntEnz-EBI ]   1.14.99.38 [ BRENDA ]   1.14.99.38 [ KEGG ]   
PhosPhoSitePlusO95992
Domains : Interpro (EBI)Fatty_acid_hydroxylase   
Domain families : Pfam (Sanger)FA_hydroxylase (PF04116)   
Domain families : Pfam (NCBI)pfam04116   
Conserved Domain (NCBI)CH25H
DMDM Disease mutations9023
Blocks (Seattle)CH25H
SuperfamilyO95992
Human Protein AtlasENSG00000138135
Peptide AtlasO95992
HPRD05183
IPIIPI00022560   
Ppoteio Anteraction databases
DIP (DOE-UCLA)O95992
IntAct (EBI)O95992
FunCoupENSG00000138135
BioGRIDCH25H
STRING (EMBL)CH25H
ZODIACCH25H
Ontologies - Pathways
QuickGOO95992
Ontology : AmiGOcholesterol 25-hydroxylase activity  iron ion binding  endoplasmic reticulum membrane  cytosol  lipid metabolic process  bile acid biosynthetic process  cholesterol metabolic process  steroid hydroxylase activity  steroid hydroxylase activity  integral component of membrane  sterol biosynthetic process  B cell chemotaxis  oxidation-reduction process  
Ontology : EGO-EBIcholesterol 25-hydroxylase activity  iron ion binding  endoplasmic reticulum membrane  cytosol  lipid metabolic process  bile acid biosynthetic process  cholesterol metabolic process  steroid hydroxylase activity  steroid hydroxylase activity  integral component of membrane  sterol biosynthetic process  B cell chemotaxis  oxidation-reduction process  
Pathways : KEGGPrimary bile acid biosynthesis   
NDEx NetworkCH25H
Atlas of Cancer Signalling NetworkCH25H
Wikipedia pathwaysCH25H
Orthology - Evolution
OrthoDB9023
GeneTree (enSembl)ENSG00000138135
Phylogenetic Trees/Animal Genes : TreeFamCH25H
HOVERGENO95992
HOGENOMO95992
Homologs : HomoloGeneCH25H
Homology/Alignments : Family Browser (UCSC)CH25H
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCH25H [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CH25H
dbVarCH25H
ClinVarCH25H
1000_GenomesCH25H 
Exome Variant ServerCH25H
ExAC (Exome Aggregation Consortium)CH25H (select the gene name)
Genetic variants : HAPMAP9023
Genomic Variants (DGV)CH25H [DGVbeta]
DECIPHERCH25H [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCH25H 
Mutations
ICGC Data PortalCH25H 
TCGA Data PortalCH25H 
Broad Tumor PortalCH25H
OASIS PortalCH25H [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCH25H  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCH25H
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CH25H
DgiDB (Drug Gene Interaction Database)CH25H
DoCM (Curated mutations)CH25H (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CH25H (select a term)
intoGenCH25H
Cancer3DCH25H(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604551   
Orphanet
MedgenCH25H
Genetic Testing Registry CH25H
NextProtO95992 [Medical]
TSGene9023
GENETestsCH25H
Target ValidationCH25H
Huge Navigator CH25H [HugePedia]
snp3D : Map Gene to Disease9023
BioCentury BCIQCH25H
ClinGenCH25H
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9023
PA26443
Clinical trialCH25H
Miscellaneous
canSAR (ICR)CH25H (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCH25H
EVEXCH25H
GoPubMedCH25H
iHOPCH25H
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:04:45 CEST 2017

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