Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79094
MIM: 614587
HGNC: 28680
Ensembl: ENSG00000128965
Variants:
dbSNP: 79094
ClinVar: 79094
TCGA: ENSG00000128965
COSMIC: CHAC1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000128965 | ENST00000444189 | Q9BUX1 |
| ENSG00000128965 | ENST00000487220 | H0YK90 |
| ENSG00000128965 | ENST00000617768 | Q9BUX1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38769193 | 2024 | Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer. | 0 |
| 38769193 | 2024 | Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer. | 0 |
| 36675091 | 2023 | CHAC1 as a Novel Contributor of Ferroptosis in Retinal Pigment Epithelial Cells with Oxidative Damage. | 12 |
| 36916093 | 2023 | CHAC1 exacerbates LPS-induced ferroptosis and apoptosis in HK-2 cells by promoting oxidative stress. | 5 |
| 38247333 | 2023 | CHAC1 promotes cell ferroptosis and enhances radiation sensitivity in thyroid carcinoma. | 0 |
| 36675091 | 2023 | CHAC1 as a Novel Contributor of Ferroptosis in Retinal Pigment Epithelial Cells with Oxidative Damage. | 12 |
| 36916093 | 2023 | CHAC1 exacerbates LPS-induced ferroptosis and apoptosis in HK-2 cells by promoting oxidative stress. | 5 |
| 38247333 | 2023 | CHAC1 promotes cell ferroptosis and enhances radiation sensitivity in thyroid carcinoma. | 0 |
| 35930144 | 2022 | High levels of unfolded protein response component CHAC1 associates with cancer progression signatures in malignant breast cancer tissues. | 5 |
| 35930144 | 2022 | High levels of unfolded protein response component CHAC1 associates with cancer progression signatures in malignant breast cancer tissues. | 5 |
| 33728749 | 2021 | Ferroptosis-related gene CHAC1 is a valid indicator for the poor prognosis of kidney renal clear cell carcinoma. | 39 |
| 33728749 | 2021 | Ferroptosis-related gene CHAC1 is a valid indicator for the poor prognosis of kidney renal clear cell carcinoma. | 39 |
| 32949369 | 2020 | Transcriptomic analysis of the effect of (E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl) prop-2-en-1-one (DPP23) on reactive oxygen species generation in MIA PaCa-2 pancreatic cancer cells. | 0 |
| 32949369 | 2020 | Transcriptomic analysis of the effect of (E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl) prop-2-en-1-one (DPP23) on reactive oxygen species generation in MIA PaCa-2 pancreatic cancer cells. | 0 |
| 31111570 | 2019 | CHAC1 overexpression in human gastric parietal cells with Helicobacter pylori infection in the secretory canaliculi. | 10 |
Citation
Dessen P
CHAC1 (ChaC glutathione specific gamma-glutamylcyclotransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2012-03-01
Online version: http://atlasgeneticsoncology.org/gene/52619/chac1
