Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CHCHD6 (coiled-coil-helix-coiled-coil-helix domain containing 6)

Identity

Alias_symbol (synonym)MGC13016
PPP1R23
CHCM1
Mic25
Other alias
HGNC (Hugo) CHCHD6
LocusID (NCBI) 84303
Atlas_Id 54215
Location 3q21.3  [Link to chromosome band 3q21]
Location_base_pair Starts at 126704220 and ends at 126960406 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CHCHD6 (3q21.3) / CHCHD6 (3q21.3)CHCHD6 (3q21.3) / DIRC2 (3q21.1)OSBPL11 (3q21.2) / CHCHD6 (3q21.3)
PLXNA1 (3q21.3) / CHCHD6 (3q21.3)OSBPL11 3q21.2 / CHCHD6 3q21.3PLXNA1 3q21.3 / CHCHD6 3q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CHCHD6   28184
Cards
Entrez_Gene (NCBI)CHCHD6  84303  coiled-coil-helix-coiled-coil-helix domain containing 6
AliasesCHCM1; Mic25; PPP1R23
GeneCards (Weizmann)CHCHD6
Ensembl hg19 (Hinxton)ENSG00000159685 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159685 [Gene_View]  chr3:126704220-126960406 [Contig_View]  CHCHD6 [Vega]
ICGC DataPortalENSG00000159685
TCGA cBioPortalCHCHD6
AceView (NCBI)CHCHD6
Genatlas (Paris)CHCHD6
WikiGenes84303
SOURCE (Princeton)CHCHD6
Genetics Home Reference (NIH)CHCHD6
Genomic and cartography
GoldenPath hg38 (UCSC)CHCHD6  -     chr3:126704220-126960406 +  3q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHCHD6  -     3q21.3   [Description]    (hg19-Feb_2009)
EnsemblCHCHD6 - 3q21.3 [CytoView hg19]  CHCHD6 - 3q21.3 [CytoView hg38]
Mapping of homologs : NCBICHCHD6 [Mapview hg19]  CHCHD6 [Mapview hg38]
OMIM615634   
Gene and transcription
Genbank (Entrez)AK310910 AK311056 BC006123 BG192698 DN992600
RefSeq transcript (Entrez)NM_001320610 NM_032343
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CHCHD6
Cluster EST : UnigeneHs.518119 [ NCBI ]
CGAP (NCI)Hs.518119
Alternative Splicing GalleryENSG00000159685
Gene ExpressionCHCHD6 [ NCBI-GEO ]   CHCHD6 [ EBI - ARRAY_EXPRESS ]   CHCHD6 [ SEEK ]   CHCHD6 [ MEM ]
Gene Expression Viewer (FireBrowse)CHCHD6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84303
GTEX Portal (Tissue expression)CHCHD6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BRQ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BRQ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BRQ6
Splice isoforms : SwissVarQ9BRQ6
PhosPhoSitePlusQ9BRQ6
Domaine pattern : Prosite (Expaxy)CHCH (PS51808)   
Domains : Interpro (EBI)DUF737   
Domain families : Pfam (Sanger)DUF737 (PF05300)   
Domain families : Pfam (NCBI)pfam05300   
Conserved Domain (NCBI)CHCHD6
DMDM Disease mutations84303
Blocks (Seattle)CHCHD6
SuperfamilyQ9BRQ6
Human Protein AtlasENSG00000159685
Peptide AtlasQ9BRQ6
HPRD13047
IPIIPI00031622   IPI00967000   IPI00975562   IPI00789915   
Protein Interaction databases
DIP (DOE-UCLA)Q9BRQ6
IntAct (EBI)Q9BRQ6
FunCoupENSG00000159685
BioGRIDCHCHD6
STRING (EMBL)CHCHD6
ZODIACCHCHD6
Ontologies - Pathways
QuickGOQ9BRQ6
Ontology : AmiGOprotein binding  mitochondrion  mitochondrion  mitochondrial inner membrane  cytosol  cellular response to DNA damage stimulus  cristae formation  MICOS complex  
Ontology : EGO-EBIprotein binding  mitochondrion  mitochondrion  mitochondrial inner membrane  cytosol  cellular response to DNA damage stimulus  cristae formation  MICOS complex  
NDEx NetworkCHCHD6
Atlas of Cancer Signalling NetworkCHCHD6
Wikipedia pathwaysCHCHD6
Orthology - Evolution
OrthoDB84303
GeneTree (enSembl)ENSG00000159685
Phylogenetic Trees/Animal Genes : TreeFamCHCHD6
HOVERGENQ9BRQ6
HOGENOMQ9BRQ6
Homologs : HomoloGeneCHCHD6
Homology/Alignments : Family Browser (UCSC)CHCHD6
Gene fusions - Rearrangements
Fusion : MitelmanCHCHD6/DIRC2 [3q21.3/3q21.1]  
Fusion : MitelmanOSBPL11/CHCHD6 [3q21.2/3q21.3]  [t(3;3)(q21;q21)]  
Fusion : MitelmanPLXNA1/CHCHD6 [3q21.3/3q21.3]  [t(3;3)(q21;q21)]  
Fusion: TCGAOSBPL11 3q21.2 CHCHD6 3q21.3 LUAD
Fusion: TCGAPLXNA1 3q21.3 CHCHD6 3q21.3 BLCA PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHCHD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHCHD6
dbVarCHCHD6
ClinVarCHCHD6
1000_GenomesCHCHD6 
Exome Variant ServerCHCHD6
ExAC (Exome Aggregation Consortium)CHCHD6 (select the gene name)
Genetic variants : HAPMAP84303
Genomic Variants (DGV)CHCHD6 [DGVbeta]
DECIPHERCHCHD6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHCHD6 
Mutations
ICGC Data PortalCHCHD6 
TCGA Data PortalCHCHD6 
Broad Tumor PortalCHCHD6
OASIS PortalCHCHD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHCHD6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCHCHD6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CHCHD6
DgiDB (Drug Gene Interaction Database)CHCHD6
DoCM (Curated mutations)CHCHD6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHCHD6 (select a term)
intoGenCHCHD6
Cancer3DCHCHD6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615634   
Orphanet
MedgenCHCHD6
Genetic Testing Registry CHCHD6
NextProtQ9BRQ6 [Medical]
TSGene84303
GENETestsCHCHD6
Target ValidationCHCHD6
Huge Navigator CHCHD6 [HugePedia]
snp3D : Map Gene to Disease84303
BioCentury BCIQCHCHD6
ClinGenCHCHD6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84303
Chemical/Pharm GKB GenePA134899331
Clinical trialCHCHD6
Miscellaneous
canSAR (ICR)CHCHD6 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHCHD6
EVEXCHCHD6
GoPubMedCHCHD6
iHOPCHCHD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:28:13 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.